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21

Expression and localization in the fish retina of a homologue of the Alzheimer's related PS1 gene

by Archer, S, Hirano, J, Diss, JKJ, Fraser, SP, Djamgoz, MBA
Published 1998
Subjects: “...AMYLOID PRECURSOR PROTEIN...”

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22

Apolipoprotein E Isoform-Dependent Effects on Human Amyloid Precursor Protein/Aβ-Induced Behavioral...

by Holden, Sarah, Kundu, Payel, Torres, Eileen R. S., Sudhakar, Reetesh, Krenik, Destine, Grygoryev, Dmytro, Turker, Mitchel S., Raber, Jacob
Published in Frontiers in Aging Neuroscience (2022)
“...Mice expressing human amyloid precursor protein (APP) containing the dominant Swedish and Iberian...”

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23

Apolipoprotein E Isoform-Dependent Effects on Human Amyloid Precursor Protein/Aβ-Induced Behavioral...

by Holden, Sarah, Kundu, Payel, Torres, Eileen R. S., Sudhakar, Reetesh, Krenik, Destine, Grygoryev, Dmytro, Turker, Mitchel S., Raber, Jacob
Published in Frontiers in Aging Neuroscience (2022)
“...Mice expressing human amyloid precursor protein (APP) containing the dominant Swedish and Iberian...”

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24

Image_4_Apolipoprotein E Isoform-Dependent Effects on Human Amyloid Precursor Protein/Aβ-Induced...

by Sarah Holden, Payel Kundu, Eileen R. S. Torres, Reetesh Sudhakar, Destine Krenik, Dmytro Grygoryev, Mitchel S. Turker, Jacob Raber
Published 2022
Subjects: “...amyloid precursor protein...”

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25

Image_1_Apolipoprotein E Isoform-Dependent Effects on Human Amyloid Precursor Protein/Aβ-Induced...

by Sarah Holden, Payel Kundu, Eileen R. S. Torres, Reetesh Sudhakar, Destine Krenik, Dmytro Grygoryev, Mitchel S. Turker, Jacob Raber
Published 2022
Subjects: “...amyloid precursor protein...”

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26

Image_2_Apolipoprotein E Isoform-Dependent Effects on Human Amyloid Precursor Protein/Aβ-Induced...

by Sarah Holden, Payel Kundu, Eileen R. S. Torres, Reetesh Sudhakar, Destine Krenik, Dmytro Grygoryev, Mitchel S. Turker, Jacob Raber
Published 2022
Subjects: “...amyloid precursor protein...”

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27

Image_3_Apolipoprotein E Isoform-Dependent Effects on Human Amyloid Precursor Protein/Aβ-Induced...

by Sarah Holden, Payel Kundu, Eileen R. S. Torres, Reetesh Sudhakar, Destine Krenik, Dmytro Grygoryev, Mitchel S. Turker, Jacob Raber
Published 2022
Subjects: “...amyloid precursor protein...”

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28

Data_Sheet_1_Apolipoprotein E Isoform-Dependent Effects on Human Amyloid Precursor Protein/Aβ...

by Sarah Holden, Payel Kundu, Eileen R. S. Torres, Reetesh Sudhakar, Destine Krenik, Dmytro Grygoryev, Mitchel S. Turker, Jacob Raber
Published 2022
Subjects: “...amyloid precursor protein...”

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29

Charakterisierung eines Dimerisierungsmotivs in der Aβ-Region des Amyloid- Vorläuferproteins : Mechanismus der Aβ-Entstehung : Characterization of a dimerization motif within the Aβ region of the Amyloid precursor protein : mechanism of Aβ generation

by Münter, Lisa-Marie
Published 2008
“...). Processing of the amyloid precursor protein (APP) by β- and g-secretases leads to the generation of Aβ...”

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30

Pulsed Hydrogen–Deuterium Exchange Reveals Altered Structures and Mechanisms in the Aggregation of Familial Alzheimer’s Disease Mutants

by Eva Illes-Toth (697547), Georg Meisl (1474477), Don L. Rempel (1500076), Tuomas P. J. Knowles (7319003), Michael L. Gross (1319688)
Published 1753
Subjects: “...Amyloid Precursor Protein...”

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31

The Arctic Alzheimer mutation enhances sensitivity to toxic stress in human neuroblastoma cells

by Sennvik, Kristina, Nilsberth, Camilla, Stenh, Charlotte, Lannfelt, Lars, Benedikz, Eirikur
Published 2002
“...The E693G (Arctic) mutation of the amyloid precursor protein was recently found to lead to early...”

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32

探討磷脂質對野生型與突變型貝塔類澱粉胜?聚集行為的影響

by 林耿琦, Lin, Keng-Chi
Published 2010
“...研究證實，疏水性之β-類澱粉胜肽(β-amyloid peptide, Aβ)為老化癍塊中的主要蛋白質成份，此胜肽來自於β-類澱粉前趨蛋白(β-amyloid precursor protein...”

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33

Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer's disease.

by George, Sonia, Rönnbäck, Annica, Gouras, Gunnar, Petit, Géraldine, Grueninger, Fiona, Winblad, Bengt, Graff, Caroline, Brundin, Patrik
Published in Acta Neuropathologica Communications (2014)
“... in the human brain. In a transgenic (Tg) mouse model of AD expressing amyloid precursor protein (APP...”

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34

Environment‐ and mutation‐dependent aggregation behavior of Alzheimer amyloid β‐protein

by Yamamoto, Naoki, Hasegawa, Kazuhiro, Matsuzaki, Katsumi, Naiki, Hironobu, Yanagisawa, Katsuhiko
Published in Journal of Neurochemistry (2004)
“.... Furthermore, hereditary variants of amyloid β‐protein, which are caused by amyloid precursor protein gene...”

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35

The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation.

by Nilsberth, C, Westlind-Danielsson, A, Eckman, CB, Condron, MM, Axelman, K, Forsell, C, Stenh, C, Luthman, J, Teplow, DB, Younkin, SG, Näslund, J, Lannfelt, L
Published 2001
“... increased amyloid beta-protein (Abeta) levels. Here we present studies of a pathogenic amyloid precursor...”

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36

Aβ Oligomer-Mediated Long-Term Potentiation Impairment Involves Protein Phosphatase 1-Dependent Mechanisms

by Knobloch, Marlen, Farinelli, Mélissa, Konietzko, Uwe, Nitsch, Roger M., Mansuy, Isabelle M.
Published in Journal of Neuroscience (2007)
“...Amyloid β (Aβ) oligomers are derived from proteolytic cleavage of amyloid precursor protein (APP...”

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37

Vascular β-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAβ mice

by Merlini, Mario, Meyer, Eric, Ulmann-Schuler, Alexandra, Nitsch, Roger
Published 2018
“... in transgenic arctic β-amyloid (arcAβ) mice expressing human amyloid precursor protein (APP) with both...”

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38

Familial Alzheimer’s disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vi...

by Tackenberg, Christian, Kulic, Luka, Nitsch, Roger M.
Published in PLOS Neglected Tropical Diseases (2020)
“... or in the gene encoding for the amyloid precursor protein (APP). Proteolytic cleavage of APP generates the β...”

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39

Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer’s disease

by George, Sonia, Rönnbäck, Annica, Gouras, Gunnar K, Petit, Géraldine H, Grueninger, Fiona, Winblad, Bengt, Graff, Caroline, Brundin, Patrik
Published 2014
“... spatiotemporal pattern in the human brain. In a transgenic (Tg) mouse model of AD expressing amyloid precursor...”

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40

The Arctic/Swedish APP mutation alters the impact of chronic stress on cognition in mice

by Cortese, A., Delgado-Morales, R., Almeida, O., Romberg, C.
Published in European Journal of Neuroscience (2019)
“... the processing of amyloid precursor protein (APP) to beta-amyloid (A beta). However, the precise relationship...”

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