Search Results

The Arctic mutation interferes with processing of the amyloid precursor protein ;

by Stenh, Charlotte, Nilsberth, Camilla, Hammarb??ck, Josefin, Engvall, Benita, N??slund, Jan, Lannfelt, Lars
Published in NeuroReport (2002)

The amyloid precursor protein of Alzheimer’s disease associates with axoplasmic organelles (596.10)

by Stevenson, James, Moran, Sean, Cyr, Jennifer, DeGiorgis, Joseph
Published in The FASEB Journal (2014)

Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein...

by Schilling, S, Pradhan, A, Heesch, A, Helbig, A, Blennow, K, Koch, C, Bertgen, L, Koo, EH, Brinkmalm, G, Zetterberg, H, Kins, S, Eggert, S
Published 2023

Syzygium aromaticum ethanol extract reduces AlCl3-induced neurotoxicity in mice brain through regulation of amyloid precursor protein and oxidative stress gene expression

by Sanila Amber, Syed Adnan Ali Shah, Touqeer Ahmed, Saadia Zahid
Published in Asian Pacific Journal of Tropical Medicine (2018)

Mitochondrial dysfunction in a transgenic mouse model expressing human amyloid precursor protein ( APP) with the Arctic mutation

by Rönnbäck, Annica, Pavlov, Pavel. F., Mansory, Mansorah, Gonze, Prisca, Marlière, Nicolas, Winblad, Bengt, Graff, Caroline, Behbahani, Homira
Published in Journal of Neurochemistry (2015)

Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein...

by Sandra Schilling, Ajay Pradhan, Amelie Heesch, Andrea Helbig, Kaj Blennow, Christian Koch, Lea Bertgen, Edward H. Koo, Gunnar Brinkmalm, Henrik Zetterberg, Stefan Kins, Simone Eggert
Published in Acta Neuropathologica Communications (2023)

Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein...

by Schilling, Sandra, Pradhan, Ajay, Heesch, Amelie, Helbig, Andrea, Blennow, Kaj, Koch, Christian, Bertgen, Lea, Koo, Edward H., Brinkmalm, Gunnar, Zetterberg, Henrik, Eggert, Simone
Published in Acta Neuropathologica Communications (2023)

Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein...

by Schilling, S., Pradhan, A., Heesch, A., Helbig, A., Blennow, K., Koch, C., Bertgen, L., Koo, E., Brinkmalm, G., Zetterberg, H., Kins, S., Eggert, S.
Published in Acta Neuropathologica Communications (2023)

The Arctic Alzheimer mutation favors intracellular amyloid‐β production by making amyloid precursor protein less available to α‐secretase

by Sahlin, Charlotte, Lord, Anna, Magnusson, Kristina, Englund, Hillevi, Almeida, Claudia G., Greengard, Paul, Nyberg, Fred, Gouras, Gunnar K., Lannfelt, Lars, Nilsson, Lars N.G.
Published in Journal of Neurochemistry (2007)

Apolipoprotein E Isoform-Dependent Effects on Human Amyloid Precursor Protein/Aβ-Induced Behavioral...

by Sarah Holden, Payel Kundu, Eileen R. S. Torres, Reetesh Sudhakar, Destine Krenik, Dmytro Grygoryev, Mitchel S. Turker, Jacob Raber
Published in Frontiers in Aging Neuroscience (2022)

Amyloid-β plaque formation and reactive gliosis are required for induction of cognitive deficits in App knock-in mouse models of Alzheimer’s disease

by Yasufumi Sakakibara, Michiko Sekiya, Takashi Saito, Takaomi C. Saido, Koichi M. Iijima
Published in BMC Neuroscience (2019)

Cognitive and emotional alterations in App knock-in mouse models of Aβ amyloidosis

by Yasufumi Sakakibara, Michiko Sekiya, Takashi Saito, Takaomi C. Saido, Koichi M. Iijima
Published in BMC Neuroscience (2018)

Expression and localization in the fish retina of a homologue of the Alzheimer's related PS1 gene

by Archer, S, Hirano, J, Diss, JKJ, Fraser, SP, Djamgoz, MBA
Published 1998

Expression and localization in the fish retina of a homologue of the Alzheimer's related PS1 gene

by Archer, S, Hirano, J, Diss, JKJ, Fraser, SP, Djamgoz, MBA
Published 1998

Apolipoprotein E Isoform-Dependent Effects on Human Amyloid Precursor Protein/Aβ-Induced Behavioral...

by Holden, Sarah, Kundu, Payel, Torres, Eileen R. S., Sudhakar, Reetesh, Krenik, Destine, Grygoryev, Dmytro, Turker, Mitchel S., Raber, Jacob
Published in Frontiers in Aging Neuroscience (2022)

The Arctic Alzheimer mutation enhances sensitivity to toxic stress in human neuroblastoma cells

by Sennvik, Kristina, Nilsberth, Camilla, Stenh, Charlotte, Lannfelt, Lars, Benedikz, Eirikur
Published 2002

Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer's disease.

by George, Sonia, Rönnbäck, Annica, Gouras, Gunnar, Petit, Géraldine, Grueninger, Fiona, Winblad, Bengt, Graff, Caroline, Brundin, Patrik
Published in Acta Neuropathologica Communications (2014)

Environment‐ and mutation‐dependent aggregation behavior of Alzheimer amyloid β‐protein

by Yamamoto, Naoki, Hasegawa, Kazuhiro, Matsuzaki, Katsumi, Naiki, Hironobu, Yanagisawa, Katsuhiko
Published in Journal of Neurochemistry (2004)

The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation.

by Nilsberth, C, Westlind-Danielsson, A, Eckman, CB, Condron, MM, Axelman, K, Forsell, C, Stenh, C, Luthman, J, Teplow, DB, Younkin, SG, Näslund, J, Lannfelt, L
Published 2001

Familial Alzheimer’s disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vi...

by Tackenberg, Christian, Kulic, Luka, Nitsch, Roger M.
Published in PLOS Neglected Tropical Diseases (2020)