Search Results

Cancer as a complex phenotype: pattern of cancer distribution within and beyond the nuclear family

by Amundadottir, Laufey T, Thorvaldsson, Sverrir, Gudbjartsson, Daniel F, Sulem, Patrick, Kristjansson, Kristleifur, Arnason, Sigurdur, Gulcher, Jeffrey R, Bjornsson, Johannes, Kong, Augustine, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in PLoS Medicine (2004)

Large-scale whole-genome sequencing of the Icelandic population

by Gudbjartsson, Daniel F, Helgason, Hannes, Gudjonsson, Sigurjon A, Zink, Florian, Oddson, Asmundur, Gylfason, Arnaldur, Besenbacher, Soren, Magnusson, Gisli, Halldorsson, Bjarni V, Hjartarson, Eirikur, Sigurdsson, Gunnar Th, Stacey, Simon N, Frigge, Michael L, Holm, Hilma, Saemundsdottir, Jona, Helgadottir, Hafdis Th, Johannsdottir, Hrefna, Sigfusson, Gunnlaugur, Thorgeirsson, Gudmundur, Sverrisson, Jon Th, Gretarsdottir, Solveig, Walters, G Bragi, Rafnar, Thorunn, Thjodleifsson, Bjarni, Bjornsson, Einar S, Olafsson, Sigurdur, Thorarinsdottir, Hildur, Steingrimsdottir, Thora, Gudmundsdottir, Thora S, Theodors, Asgeir, Jonasson, Jon G, Sigurdsson, Asgeir, Bjornsdottir, Gyda, Jonsson, Jon J, Thorarensen, Olafur, Ludvigsson, Petur, Gudbjartsson, Hakon, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Olafsson, Isleifur, Arnar, David O, Magnusson, Olafur Th, Kong, Augustine, Masson, Gisli, Thorsteinsdottir, Unnur, Helgason, Agnar, Sulem, Patrick, Stefansson, Kari
Published in Nature Genetics (2015)

European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene.

by Rafnar, Thorunn, Vermeulen, Sita H, Sulem, Patrick, Thorleifsson, Gudmar, Aben, Katja K, Witjes, J Alfred, Grotenhuis, Anne J, Verhaegh, Gerald W, Hulsbergen-van de Kaa, Christina A, Besenbacher, Soren, Gudbjartsson, Daniel, Stacey, Simon N, Gudmundsson, Julius, Johannsdottir, Hrefna, Bjarnason, Hjordis, Zanon, Carlo, Helgadottir, Hafdis, Jonasson, Jon Gunnlaugur, Tryggvadottir, Laufey, Jonsson, Eirikur, Geirsson, Gudmundur, Nikulasson, Sigfus, Petursdottir, Vigdis, Bishop, D Timothy, Chung-Sak, Sei, Choudhury, Ananya, Elliott, Faye, Barrett, Jennifer H, Knowles, Margaret A, de Verdier, Petra J, Ryk, Charlotta, Lindblom, Annika, Rudnai, Peter, Gurzau, Eugene, Koppova, Kvetoslava, Vineis, Paolo, Polidoro, Silvia, Guarrera, Simonetta, Sacerdote, Carlotta, Panadero, Angeles, Sanz-Velez, José I, Sanchez, Manuel, Valdivia, Gabriel, Garcia-Prats, Maria D, Hengstler, Jan G, Selinski, Silvia, Gerullis, Holger, Ovsiannikov, Daniel, Khezri, Abdolaziz, Aminsharifi, Alireza
Published in Human Molecular Genetics (2012)

Genetic correction of PSA values using sequence variants associated with PSA levels

by Gudmundsson, Julius, Besenbacher, Soren, Sulem, Patrick, Gudbjartsson, Daniel F, Olafsson, Isleifur, Arinbjarnarson, Sturla, Agnarsson, Bjarni A, Benediktsdottir, Kristrun R, Isaksson, Helgi J, Kostic, Jelena P, Gudjonsson, Sigurjon A, Stacey, Simon N, Gylfason, Arnaldur, Sigurdsson, Asgeir, Holm, Hilma, Bjornsdottir, Unnur S, Eyjolfsson, Gudmundur I, Navarrete, Sebastian, Fuertes, Fernando, Garcia-Prats, Maria D, Polo, Eduardo, Checherita, Ionel A, Jinga, Mariana, Badea, Paula, Aben, Katja K, Schalken, Jack A, van Oort, Inge M, Sweep, Fred C, Helfand, Brian T, Davis, Michael, Donovan, Jenny L, Hamdy, Freddie C, Kristjansson, Kristleifur, Gulcher, Jeffrey R, Masson, Gisli, Kong, Augustine, Catalona, William J, Mayordomo, Jose I, Geirsson, Gudmundur, Einarsson, Gudmundur V, Barkardottir, Rosa B, Jonsson, Eirikur, Jinga, Viorel, Mates, Dana, Kiemeney, Lambertus A, Neal, David E, Thorsteinsdottir, Unnur, Rafnar, Thorunn, Stefansson, Kari
Published in Science Translational Medicine (2011)

Large-scale whole-genome sequencing of the Icelandic population.

by Gudbjartsson, Daniel F, Helgason, Hannes, Gudjonsson, Sigurjon A, Zink, Florian, Oddson, Asmundur, Gylfason, Arnaldur, Besenbacher, Soren, Magnusson, Gisli, Halldorsson, Bjarni V, Hjartarson, Eirikur, Sigurdsson, Gunnar Th, Stacey, Simon N, Frigge, Michael L, Holm, Hilma, Saemundsdottir, Jona, Helgadottir, Hafdis Th, Johannsdottir, Hrefna, Sigfusson, Gunnlaugur, Thorgeirsson, Gudmundur, Sverrisson, Jon Th, Gretarsdottir, Solveig, Walters, G Bragi, Rafnar, Thorunn, Thjodleifsson, Bjarni, Bjornsson, Einar S, Olafsson, Sigurdur, Thorarinsdottir, Hildur, Steingrimsdottir, Thora, Gudmundsdottir, Thora S, Theodors, Asgeir, Jonasson, Jon G, Sigurdsson, Asgeir, Bjornsdottir, Gyda, Jonsson, Jon J, Thorarensen, Olafur, Ludvigsson, Petur, Gudbjartsson, Hakon, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Olafsson, Isleifur, Arnar, David O, Magnusson, Olafur Th, Kong, Augustine, Masson, Gisli, Thorsteinsdottir, Unnur, Helgason, Agnar, Sulem, Patrick, Stefansson, Kari
Published in Nature Genetics (2015)

Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer.

by Gudmundsson, Julius, Sulem, Patrick, Rafnar, Thorunn, Bergthorsson, Jon T, Manolescu, Andrei, Gudbjartsson, Daniel, Agnarsson, Bjarni A, Sigurdsson, Asgeir, Benediktsdottir, Kristrun R, Blondal, Thorarinn, Jakobsdottir, Margret, Stacey, Simon N, Kostic, Jelena, Kristinsson, Kari T, Birgisdottir, Birgitta, Ghosh, Shyamali, Magnusdottir, Droplaug N, Thorlacius, Steinunn, Thorleifsson, Gudmar, Zheng, S Lilly, Sun, Jielin, Chang, Bao-Li, Elmore, J Bradford, Breyer, Joan P, McReynolds, Kate M, Bradley, Kevin M, Yaspan, Brian L, Wiklund, Fredrik, Stattin, Par, Lindström, Sara, Adami, Hans-Olov, McDonnell, Shannon K, Schaid, Daniel J, Cunningham, Julie M, Wang, Liang, Cerhan, James R, St Sauver, Jennifer L, Isaacs, Sara D, Wiley, Kathleen E, Partin, Alan W, Walsh, Patrick C, Polo, Sonia, Ruiz-Echarri, Manuel, Navarrete, Sebastian, Fuertes, Fernando, Saez, Berta, Godino, Javier, Weijerman, Philip C, Swinkels, Dorine W, Aben, Katja K
Published in Nature Genetics (2009)

Genome-wide significant association between a sequence variant at 15q15.2 and lung cancer risk

by Rafnar, Thorunn, Sulem, Patrick, Besenbacher, Soren, Gudbjartsson, Daniel F, Zanon, Carlo, Gudmundsson, Julius, Stacey, Simon N, Kostic, Jelena P, Thorgeirsson, Thorgeir E, Thorleifsson, Gudmar, Bjarnason, Hjordis, Skuladottir, Halla, Gudbjartsson, Tomas, Isaksson, Helgi J, Isla, Dolores, Murillo, Laura, García-Prats, Maria D, Panadero, Angeles, Aben, Katja K H, Vermeulen, Sita H, van der Heijden, Henricus F M, Feser, William J, Miller, York E, Bunn, Paul A, Kong, Augustine, Wolf, Holly J, Franklin, Wilbur A, Mayordomo, Jose I, Kiemeney, Lambertus A, Jonsson, Steinn, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Cancer Research (2011)

The CRTAC1 protein in plasma associates with osteoarthritis and predicts progression to joint replacements : A Large-Scale Proteomics Scan in Iceland

by Styrkarsdottir, Unnur, Lund, Sigrun H., Sævarsdóttir, Sædís, Magnusson, Magnus I., Gunnarsdottir, Kristbjorg, Norddahl, Gudmundur L., Frigge, Michael L., Ivarsdottir, Erna V., Bjornsdottir, Gyda, Holm, Hilma, Thorgeirsson, Gudmundur, Rafnar, Thorunn, Jónsdóttir, Ingileif, Ingvarsson, Þorvaldur, Jónsson, Helgi, Sulem, Patrick, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel, Stefansson, Kari
Published in Arthritis & Rheumatology (2021)

Parental origin of sequence variants associated with complex diseases

by Kong, Augustine, Steinthorsdottir, Valgerdur, Masson, Gisli, Thorleifsson, Gudmar, Sulem, Patrick, Besenbacher, Søren, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Kristinsson, Kari Th, Jonasdottir, Adalbjorg, Frigge, Michael L, Gylfason, Arnaldur, Olason, Pall I, Gudjonsson, Sigurjon A, Sverrisson, Sverrir, Stacey, Simon N, Sigurgeirsson, Bardur, Benediktsdottir, Kristrun R, Sigurdsson, Helgi, Jonsson, Thorvaldur, Benediktsson, Rafn, Olafsson, Jon H, Johannsson, Oskar Th, Hreidarsson, Astradur B, Sigurdsson, Gunnar, Ferguson-Smith, Anne C, Gudbjartsson, Daniel F, Thorsteinsdottir, Unnur, Stefansson, Kari, Lauritzen, Torsten
Published in Nature (2009)

Identification of sequence variants influencing immunoglobulin levels.

by Jonsson, Stefan, Sveinbjornsson, Gardar, de Lapuente Portilla, Aitzkoa Lopez, Swaminathan, Bhairavi, Plomp, Rosina, Dekkers, Gillian, Ajore, Ram, Ali, Mina, Bentlage, Arthur E H, Elmér, Evelina, Eyjolfsson, Gudmundur I, Gudjonsson, Sigurjon A, Gullberg, Urban, Gylfason, Arnaldur, Halldorsson, Bjarni V, Hansson, Markus, Holm, Hilma, Johansson, Åsa, Johnsson, Ellinor, Jonasdottir, Aslaug, Ludviksson, Bjorn R, Oddsson, Asmundur, Olafsson, Isleifur, Olafsson, Sigurgeir, Sigurdardottir, Olof, Sigurdsson, Asgeir, Stefansdottir, Lilja, Masson, Gisli, Sulem, Patrick, Wuhrer, Manfred, Wihlborg, Anna-Karin, Thorleifsson, Gudmar, Gudbjartsson, Daniel F, Thorsteinsdottir, Unnur, Vidarsson, Gestur, Jonsdottir, Ingileif, Nilsson, Björn, Stefansson, Kari
Published in Nature Genetics (2017)

Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility

by Gudmundsson, Julius, Sulem, Patrick, Gudbjartsson, Daniel F, Blondal, Thorarinn, Gylfason, Arnaldur, Agnarsson, Bjarni A, Benediktsdottir, Kristrun R, Magnusdottir, Droplaug N, Orlygsdottir, Gudbjorg, Jakobsdottir, Margret, Stacey, Simon N, Sigurdsson, Asgeir, Wahlfors, Tiina, Tammela, Teuvo, Breyer, Joan P, McReynolds, Kate M, Bradley, Kevin M, Saez, Berta, Godino, Javier, Navarrete, Sebastian, Fuertes, Fernando, Murillo, Laura, Polo, Eduardo, Aben, Katja K, van Oort, Inge M, Suarez, Brian K, Helfand, Brian T, Kan, Donghui, Zanon, Carlo, Frigge, Michael L, Kristjansson, Kristleifur, Gulcher, Jeffrey R, Einarsson, Gudmundur V, Jonsson, Eirikur, Catalona, William J, Mayordomo, Jose I, Kiemeney, Lambertus A, Smith, Jeffrey R, Schleutker, Johanna, Barkardottir, Rosa B, Kong, Augustine, Thorsteinsdottir, Unnur, Rafnar, Thorunn, Stefansson, Kari
Published in Nature Genetics (2009)

A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancer.

by Gudmundsson, Julius, Sulem, Patrick, Gudbjartsson, Daniel F, Masson, Gisli, Agnarsson, Bjarni A, Benediktsdottir, Kristrun R, Sigurdsson, Asgeir, Magnusson, Olafur Th, Gudjonsson, Sigurjon A, Magnusdottir, Droplaug N, Johannsdottir, Hrefna, Helgadottir, Hafdis Th, Stacey, Simon N, Jonasdottir, Adalbjorg, Olafsdottir, Stefania B, Thorleifsson, Gudmar, Jonasson, Jon G, Tryggvadottir, Laufey, Navarrete, Sebastian, Fuertes, Fernando, Helfand, Brian T, Hu, Qiaoyan, Csiki, Irma E, Mates, Ioan N, Jinga, Viorel, Aben, Katja K H, van Oort, Inge M, Vermeulen, Sita H, Donovan, Jenny L, Hamdy, Freddy C, Ng, Chi-Fai, Chiu, Peter K F, Lau, Kin-Mang, Ng, Maggie C Y, Gulcher, Jeffrey R, Kong, Augustine, Catalona, William J, Mayordomo, Jose I, Einarsson, Gudmundur V, Barkardottir, Rosa B, Jonsson, Eirikur, Mates, Dana, Neal, David E, Kiemeney, Lambertus A, Thorsteinsdottir, Unnur, Rafnar, Thorunn, Stefansson, Kari
Published in Nature Genetics (2013)

Parental origin of sequence variants associated with complex diseases

by Kong, Augustine, Steinthorsdottir, Valgerdur, Masson, Gisli, Thorleifsson, Gudmar, Sulem, Patrick, Besenbacher, Soren, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Kristinsson, Kari Th, Jonasdottir, Adalbjorg, Frigge, Michael L, Gylfason, Arnaldur, Olason, Pall I, Gudjonsson, Sigurjon A, Sverrisson, Sverrir, Stacey, Simon N, Sigurgeirsson, Bardur, Benediktsdottir, Kristrun R, Sigurdsson, Helgi, Jonsson, Thorvaldur, Benediktsson, Rafn, Olafsson, Jon H, Johannsson, Oskar Th, Hreidarsson, Astradur B, Sigurdsson, Gunnar, Ferguson-Smith, Anne C, Gudbjartsson, Daniel F, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature (2011)

Rate of de novo mutations and the importance of father's age to disease risk.

by Kong, Augustine, Frigge, Michael L, Masson, Gisli, Besenbacher, Soren, Sulem, Patrick, Magnusson, Gisli, Gudjonsson, Sigurjon A, Sigurdsson, Asgeir, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Wong, Wendy S W, Sigurdsson, Gunnar, Walters, G Bragi, Steinberg, Stacy, Helgason, Hannes, Thorleifsson, Gudmar, Gudbjartsson, Daniel F, Helgason, Agnar, Magnusson, Olafur Th, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature (2013)

Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits.

by Styrkarsdottir, Unnur, Thorleifsson, Gudmar, Sulem, Patrick, Gudbjartsson, Daniel F, Sigurdsson, Asgeir, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Oddsson, Asmundur, Helgason, Agnar, Magnusson, Olafur T, Walters, G Bragi, Frigge, Michael L, Helgadottir, Hafdis T, Johannsdottir, Hrefna, Bergsteinsdottir, Kristin, Ogmundsdottir, Margret H, Center, Jacqueline R, Nguyen, Tuan V, Eisman, John A, Christiansen, Claus, Steingrimsson, Erikur, Jonasson, Jon G, Tryggvadottir, Laufey, Eyjolfsson, Gudmundur I, Theodors, Asgeir, Jonsson, Thorvaldur, Ingvarsson, Thorvaldur, Olafsson, Isleifur, Rafnar, Thorunn, Kong, Augustine, Sigurdsson, Gunnar, Masson, Gisli, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature (2014)

Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes.

by Steinthorsdottir, Valgerdur, Thorleifsson, Gudmar, Sulem, Patrick, Helgason, Hannes, Grarup, Niels, Sigurdsson, Asgeir, Helgadottir, Hafdis T, Johannsdottir, Hrefna, Magnusson, Olafur T, Gudjonsson, Sigurjon A, Justesen, Johanne M, Harder, Marie N, Jørgensen, Marit E, Christensen, Cramer, Brandslund, Ivan, Sandbæk, Annelli, Lauritzen, Torsten, Vestergaard, Henrik, Linneberg, Allan, Jørgensen, Torben, Hansen, Torben, Daneshpour, Maryam S, Fallah, Mohammad-Sadegh, Hreidarsson, Astradur B, Sigurdsson, Gunnar, Azizi, Fereidoun, Benediktsson, Rafn, Masson, Gisli, Helgason, Agnar, Kong, Augustine, Gudbjartsson, Daniel F, Pedersen, Oluf, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature Genetics (2014)

Population-level deficit of homozygosity unveils CPSF3 as an intellectual disability syndrome gene

by Árnadóttir, Guðný Anna, Oddsson, Asmundur, Jensson, Brynjar O., Gisladottir, Svanborg, Simon, Mariella T., Arnthorsson, Asgeir O., Katrinardottir, Hildigunnur, Fridriksdottir, Run, Ivarsdottir, Erna V., Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Barrick, Rebekah, Saemundsdottir, Jona, le Roux, Louise, Oskarsson, Gudjon R., Ásmundsson, Jurate, Steffensen, Þóra Steinunn, Gudmundsson, Kjartan R., Ludvigsson, Petur, Jonsson, Jon J., Masson, Gisli, Jonsdottir, Ingileif, Holm, Hilma, Jonasson, Jon G., Magnusson, Olafur Th, Thorarensen, Olafur, Abdenur, Jose, Norddahl, Gudmundur L., Gudbjartsson, Daniel F., Bjornsson, Hans T., Þorsteinsdóttir, Unnur, Sulem, Patrick, Stefánsson, Kári
Published in Nature Communications (2022)

European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene

by Rafnar, Thorunn, Vermeulen, Sita H, Sulem, Patrick, Thorleifsson, Gudmar, Aben, Katja K, Witjes, J Alfred, Grotenhuis, Anne J, Verhaegh, Gerald W, Hulsbergen-van de Kaa, Christina A, Besenbacher, Soren, Gudbjartsson, Daniel, Stacey, Simon N, Gudmundsson, Julius, Johannsdottir, Hrefna, Bjarnason, Hjordis, Zanon, Carlo, Helgadottir, Hafdis, Jonasson, Jon Gunnlaugur, Tryggvadottir, Laufey, Jonsson, Eirikur, Geirsson, Gudmundur, Nikulasson, Sigfus, Petursdottir, Vigdis, Bishop, D Timothy, Chung-Sak, Sei, Choudhury, Ananya, Elliott, Faye, Barrett, Jennifer H, Knowles, Margaret A, de Verdier, Petra J, Ryk, Charlotta, Lindblom, Annika, Rudnai, Peter, Gurzau, Eugene, Koppova, Kvetoslava, Vineis, Paolo, Polidoro, Silvia, Guarrera, Simonetta, Sacerdote, Carlotta, Panadero, Angeles, Sanz-Velez, José I, Sanchez, Manuel, Valdivia, Gabriel, Garcia-Prats, Maria D, Hengstler, Jan G, Selinski, Silvia, Gerullis, Holger, Ovsiannikov, Daniel, Khezri, Abdolaziz, Aminsharifi, Alireza, Malekzadeh, Mahyar, van den Berg, Leonard H, Ophoff, Roel A, Veldink, Jan H, Zeegers, Maurice P, Kellen, Eliane, Fostinelli, Jacopo, Andreoli, Daniele, Arici, Cecilia, Porru, Stefano, Buntinx, Frank, Ghaderi, Abbas, Golka, Klaus, Mayordomo, José I, Matullo, Giuseppe, Kumar, Rajiv, Steineck, Gunnar, Kiltie, Anne E, Kong, Augustine, Thorsteinsdottir, Unnur, Stefansson, Kari, Kiemeney, Lambertus A
Published in Human Molecular Genetics (2011)

Predicting the probability of death using proteomics

by Eiriksdottir, Thjodbjorg, Ardal, Steinthor, Jonsson, Benedikt A., Lund, Sigrun H., Ivarsdottir, Erna V., Norland, Kristjan, Ferkingstad, Egil, Stefansson, Hreinn, Jónsdóttir, Ingileif, Holm, Hilma, Rafnar, Thorunn, Saemundsdottir, Jona, Norddahl, Gudmundur L., Þorgeirsson, Guðmundur, Gudbjartsson, Daniel F., Sulem, Patrick, Thorsteinsdottir, Unnur, Stefansson, Kari, Úlfarsson, Magnús Örn
Published in Communications Biology (2021)

Sequence variants associating with urinary biomarkers

by Benonisdottir, Stefania, Kristjansson, Ragnar P, Oddsson, Asmundur, Steinthorsdottir, Valgerdur, Mikaelsdottir, Evgenia, Kehr, Birte, Jensson, Brynjar O, Arnadottir, Gudny A, Sulem, Gerald, Sveinbjornsson, Gardar, Kristmundsdottir, Snaedis, Ivarsdottir, Erna V, Vogel, Lotte K, Tragante, Vinicius, Gunnarsson, Bjarni, Runolfsdottir, Hrafnhildur Linnet, Arthur, Joseph G, Deaton, Aimee M, Eyjolfsson, Gudmundur I, Davidsson, Olafur B, Asselbergs, Folkert W, Hreidarsson, Astradur B, Rafnar, Thorunn, Thorleifsson, Gudmar, Edvardsson, Vidar, Sigurdsson, Gunnar, Helgadottir, Anna, Halldorsson, Bjarni V, Masson, Gisli, Holm, Hilma, Onundarson, Pall T, Indridason, Olafur S, Benediktsson, Rafn, Palsson, Runolfur, Gudbjartsson, Daniel F, Olafsson, Isleifur, Thorsteinsdottir, Unnur, Sulem, Patrick, Stefansson, Kari
Published 2019