Immunohistochemical characterisation of parasitic pneumonias of dolphins stranded in the Canary Islands

• Published in: Research in Veterinary Science
• Main Authors: Zafra Leva, Rafael, Jáber Mohamad, José Raduán, Pérez Arevalo,Jose, De La Fuente Marquez, Jesus, Arbelo Hernández, Manuel Antonio, Andrada Borzollino, Marisa Ana, Fernández Rodríguez, Antonio Jesús
• Other Authors: Fernandez, Antonio, Arbelo, Manuel, Perez, Jose, 23029634000, 7004667021, 55597088346, 55597088351, 56587483900, 6603561403, 6602991535, 56673009900, 770447, 959492, 319037, 19025, 667707, 862879, 176520, 273789, WOS:Zafra, R, WOS:Jaber, JR, WOS:Perez, J, WOS:de la Fuente, J, WOS:Arbelo, M, WOS:Andrada, M, WOS:Fernandez, A, BU-VET
• Format: Article in Journal/Newspaper
• Language: English
• Published: 0034-5288 2015
• Subjects: 240111 Patología animal; 310907 Patología; 240112 Parasitología animal; Regulatory T-Cells; Porpoise Phocoena-Phocoena; Monoclonal-Antibodies; Cross-Reactivity; Harbor Porpoises; Lesions; Infection; Immunity; Waters; Coast; Lung; Dolphin; Parasite; Immunohistochemistry; Phocoena phocoena
• Online Access: http://hdl.handle.net/10553/47415; https://doi.org/10.1016/j.rvsc.2015.03.021

This is the first work that applies immunohistochemistry in the characterisation of the inflammatory infiltrate of verminous bronchopneumonia associated with lungworm parasites in stranded dolphins. Samples from three different species (Stenella coerulealba, Stenella frontalis and Delphinus delphis) stranded in the Canary Islands were used. The most common findings found in these animals varied from bronchitis to verminous bronchopneumonia with different degree of severity. The immunohistochemical study showed variable expressions of Lysozyme, MHC-II, iNOS and IgG. The main population presenting in the inflammatory infiltrates were CD3+ lymphocytes. However, moderate number of Foxp3+ lymphocytes was found in lymph nodes even though no Foxp3+ cells were found in lung lesions in any of the samples analysed. This study revealed that lung lesions showed a chronic inflammatory infiltrate mainly composed by lymphocytes CD3+. Deeper studies are needed in order to provide a more complete scope about the infiltrates involved in these types of lesions. 212 207 0,761 1,504 Q1 Q1 SCIE