Immunohistochemical characterisation of parasitic pneumonias of dolphins stranded in the Canary Islands

This is the first work that applies immunohistochemistry in the characterisation of the inflammatory infiltrate of verminous bronchopneumonia associated with lungworm parasites in stranded dolphins. Samples from three different species (Stenella coerulealba, Stenella frontalis and Delphinus delphis)...

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Bibliographic Details
Published in:Research in Veterinary Science
Main Authors: Zafra Leva, Rafael, Jáber Mohamad, José Raduán, Pérez Arevalo,Jose, De La Fuente Marquez, Jesus, Arbelo Hernández, Manuel Antonio, Andrada Borzollino, Marisa Ana, Fernández Rodríguez, Antonio Jesús
Other Authors: Fernandez, Antonio, Arbelo, Manuel, Perez, Jose, 23029634000, 7004667021, 55597088346, 55597088351, 56587483900, 6603561403, 6602991535, 56673009900, 770447, 959492, 319037, 19025, 667707, 862879, 176520, 273789, WOS:Zafra, R, WOS:Jaber, JR, WOS:Perez, J, WOS:de la Fuente, J, WOS:Arbelo, M, WOS:Andrada, M, WOS:Fernandez, A, BU-VET
Format: Article in Journal/Newspaper
Language:English
Published: 0034-5288 2015
Subjects:
240111 Patología animal
310907 Patología
240112 Parasitología animal
Regulatory T-Cells
Porpoise Phocoena-Phocoena
Monoclonal-Antibodies
Cross-Reactivity
Harbor Porpoises
Lesions
Infection
Immunity
Waters
Coast
Lung
Dolphin
Parasite
Immunohistochemistry
Phocoena phocoena
Online Access:http://hdl.handle.net/10553/47415
https://doi.org/10.1016/j.rvsc.2015.03.021
Description
Summary:This is the first work that applies immunohistochemistry in the characterisation of the inflammatory infiltrate of verminous bronchopneumonia associated with lungworm parasites in stranded dolphins. Samples from three different species (Stenella coerulealba, Stenella frontalis and Delphinus delphis) stranded in the Canary Islands were used. The most common findings found in these animals varied from bronchitis to verminous bronchopneumonia with different degree of severity. The immunohistochemical study showed variable expressions of Lysozyme, MHC-II, iNOS and IgG. The main population presenting in the inflammatory infiltrates were CD3+ lymphocytes. However, moderate number of Foxp3+ lymphocytes was found in lymph nodes even though no Foxp3+ cells were found in lung lesions in any of the samples analysed. This study revealed that lung lesions showed a chronic inflammatory infiltrate mainly composed by lymphocytes CD3+. Deeper studies are needed in order to provide a more complete scope about the infiltrates involved in these types of lesions. 212 207 0,761 1,504 Q1 Q1 SCIE

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