Search Results

Inuit in Greenland have significantly higher heritability for anthropometric traits

by Appel, E. R., Moltke, I., Jorgensen, M. E., Bjerregaard, P., Linneberg, A., Hansen, T., Grarup, N., Albrechtsen, A.
Published in European Journal of Human Genetics (2018)

Uncovering the genetic history of the present-day Greenlandic population.

by Moltke, I, Fumagalli, M, Korneliussen, TS, Crawford, JE, Bjerregaard, P, Jørgensen, ME, Grarup, N, Gulløv, HC, Linneberg, A, Pedersen, O, Hansen, T, Nielsen, R, Albrechtsen, A
Published 2015

The genetic history of Greenlandic-European contact.

by Waples, RK, Hauptmann, AL, Seiding, I, Jørsboe, E, Jørgensen, ME, Grarup, N, Andersen, MK, Larsen, CVL, Bjerregaard, P, Hellenthal, G, Hansen, T, Albrechtsen, A, Moltke, I
Published 2021

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

by Grarup, N., Moltke, I., Jorgensen, M. E., Bjerregaard, P., Treebak, J. T., Korneliussen, T. S., Andersen, M. A., Nielsen, T. S., Krarup, N. T., Linneberg, A., Wang, J., Pedersen, O., Nielsen, R., Albrechtsen, A., Hansen, T.
Published 2014

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

by Grarup, N, Moltke, I, Jorgensen, ME, Bjerregaard, P, Treebak, JT, Korneliussen, TS, Andersen, MA, Nielsen, TS, Krarup, NT, Linneberg, A, Wang, J, Pedersen, O, Nielsen, R, Albrechtsen, A, Hansen, T
Published 2014

Selection in Europeans on fatty acid desaturases associated with dietary changes

by Buckley M. T., Racimo F., Allentoft M. E., Jensen M. K., Jonsson A., Huang H., Hormozdiari F., Sikora M., Marnetto D., Eskin E., Jorgensen M. E., Grarup N., Pedersen O., Hansen T., Kraft P., Willerslev E., Nielsen R.
Published in Molecular Biology and Evolution (2017)

Greenlandic Inuit show genetic signatures of diet and climate adaptation.

by Fumagalli, M, Moltke, I, Grarup, N, Racimo, F, Bjerregaard, P, Jørgensen, ME, Korneliussen, TS, Gerbault, P, Skotte, L, Linneberg, A, Christensen, C, Brandslund, I, Jørgensen, T, Huerta-Sánchez, E, Schmidt, EB, Pedersen, O, Hansen, T, Albrechtsen, A, Nielsen, R
Published 2015

Greenlandic Inuit show genetic signatures of diet and climate adaptation.

by Fumagalli, M, Moltke, I, Grarup, N, Racimo, F, Bjerregaard, P, Jørgensen, ME, Korneliussen, TS, Gerbault, P, Skotte, L, Linneberg, A, Christensen, C, Brandslund, I, Jørgensen, T, Huerta-Sánchez, E, Schmidt, EB, Pedersen, O, Hansen, T, Albrechtsen, A, Nielsen, R
Published in Science (2015)

Greenlandic Inuit show genetic signatures of diet and climate adaptation

by Fumagalli, M., Moltke, I., Grarup, N., Racimo, F., Bjerregaard, P., Jørgensen, M.E., Korneliussen, T.S., Gerbault, P., Skotte, L., Linneberg, A., Christensen, C., Brandslund, I., Jørgensen, T., Huerta-Sánchez, E., Schmidt, E.B., Pedersen, O., Hansen, T., Albrechtsen, A., Nielsen, R.
Published in Science (2015)

A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland

by Thuesen, A., Staeger, F., Kaci, A., Solheim, M., Aukrust, I., Jorsboe, E., Santander, C., Andersen , M., Li, Z., Gilly, A., Stinson, S., Gjesing, A., Bjerregaard, P., Pedersen, M., Larsen, C., Grarup, N., Jorgensen, M., Zeggini, E., Bjorkhaug, L., Njolstad, P., Albrechtsen, A., Moltke, I., Hansen, T.
Published in The Lancet Regional Health - Europe (2023)

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes.

by Moltke, I, Grarup, N, Jørgensen, ME, Bjerregaard, P, Treebak, JT, Fumagalli, M, Korneliussen, TS, Andersen, MA, Nielsen, TS, Krarup, NT, Gjesing, AP, Zierath, JR, Linneberg, A, Wu, X, Sun, G, Jin, X, Al-Aama, J, Wang, J, Borch-Johnsen, K, Pedersen, O, Nielsen, R, Albrechtsen, A, Hansen, T
Published 2014

A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes: results from an exome-wide association study of albuminuria

by Ahluwalia, T, Schulz, C, Waage, J, Skaaby, T, Sandholm, N, Van Zuydam, N, Charmet, R, Bork-Jensen, J, Almgren, P, Thuesen, B, Bedin, M, Brandslund, I, Christensen, C, Linneberg, A, Ahlqvist, E, Groop, P, Hadjadj, S, Tregouet, D, Jørgensen, M, Grarup, N, Pedersen, O, Simons, M, Groop, L, Orho-Melander, M, McCarthy, M, Melander, O, Rossing, P, Kilpeläinen, T, Hansen, T
Published in Diabetologia (2019)

G-allele of Intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and Type 2 diabetes through an impaired glucose-stimulated insulin release studies inv...

by Sparso, T, Bonnefond, A, Andersson, E, Bouatia-Naji, N, Holmkvist, J, Wegner, L, Grarup, N, Gjesing, AP, Banasik, K, Cavalcanti-Proenca, C, Marchand, M, Vaxillaire, M, Charpentier, G, Jarvelin, M-R, Tichet, J, Balkau, B, Marre, M, Levy-Marchal, C, Faerch, K, Borch-Johnsen, K, Jorgensen, T, Madsbad, S, Poulsen, P, Vaag, A, Dina, C, Hansen, T, Pedersen, O, Froguel, P
Published in Diabetes (2009)

Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease

by Nioi, P, Sigurdsson, A, Thorleifsson, G, Helgason, H, Agustsdottir, AB, Norddahl, GL, Helgadottir, A, Magnusdottir, A, Jonasdottir, A, Gretarsdottir, S, Jonsdottir, I, Steinthorsdottir, V, Rafnar, T, Swinkels, DW, Galesloot, TE, Grarup, N, Jørgensen, T, Vestergaard, H, Hansen, T, Lauritzen, T, Linneberg, A, Friedrich, N, Krarup, NT, Fenger, M, Abildgaard, U, Hansen, PR, Galløe, AM, Braund, PS, Nelson, CP, Hall, AS, Williams, MJ, van Rij, AM, Jones, GT, Patel, RS, Levey, AI, Hayek, S, Shah, SH, Reilly, M, Eyjolfsson, GI, Sigurdardottir, O, Olafsson, I, Kiemeney, LA, Quyyumi, AA, Rader, DJ, Kraus, WE, Samani, NJ, Pedersen, O, Thorgeirsson, G, Masson, G, Holm, H, Gudbjartsson, D, Sulem, P, Thorsteinsdottir, U, Stefansson, K
Published 2016

Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease.

by Nioi, P., Sigurdsson, A., Thorleifsson, G., Helgason, H., Agustsdottir, A. B., Norddahl, G. L., Helgadottir, A., Magnusdottir, A., Jonasdottir, A., Gretarsdottir, S., Jonsdottir, I., Steinthorsdottir, V., Rafnar, T., Swinkels, D. W., Galesloot, T. E., Grarup, N., Jørgensen, T., Vestergaard, H., Hansen, T., Lauritzen, T., Linneberg, A., Friedrich, N., Krarup, N. T., Fenger, M., Abildgaard, U., Hansen, P. R., Galløe, A. M., Braund, P. S., Nelson, C. P., Hall, A. S., Williams, M. J., van Rij, A. M., Jones, G. T., Patel, R. S., Levey, A. I., Hayek, S., Shah, S. H., Reilly, M., Eyjolfsson, G. I., Sigurdardottir, O., Olafsson, I., Kiemeney, L. A., Quyyumi, A. A., Rader, D. J., Kraus, W. E., Samani, N. J., Pedersen, O., Thorgeirsson, G., Masson, G., Holm, H., Gudbjartsson, D., Sulem, P., Thorsteinsdottir, U., Stefansson, K.
Published in New England Journal of Medicine (2016)

Variant ASGR1 associated with a reduced risk of coronary artery disease

by Nioi, P., Sigurdsson, A., Thorleifsson, G., Helgason, H., Agustsdottir, A. B., Norddahl, G. L., Helgadottir, Anna, Magnusdottir, A., Jonasdottir, A., Grétarsdóttir, Sólveig, Jonsdottir, I, Steinthorsdottir, V., Rafnar, Thorunn, Swinkels, D. W., Galesloot, T. E., Grarup, N., Jørgensen, T, Vestergaard, H., Hansen, Torben, Lauritzen, T, Linneberg, A., Friedrich, Nele, Krarup, N T, Fenger, Mogens, Abildgaard, U., Hansen, Peter R, Galløe, Anders M., Braund, P. S., Nelson, Christopher P, Hall, Alistair S, Williams, Michael J A, van Rij, Andre M, Jones, Gregory T, Patel, Sanjay R, Levey, Allan I, Hayek, S., Shah, Svati H, Reilly, Marie, Eyjolfsson, G. I., Sigurdardottir, O., Olafsson, Isleifur, Kiemeney, L. A., Quyyumi, Arshed A, Rader, Daniel J, Kraus, W. E., Samani, Nilesh J, Pedersen, O., Thorgeirsson, G., Masson, G., Holm, Hilma, Gudbjartsson, D. F., Sulem, P., Thorsteinsdottir, Unnur, Stefansson, K
Published in New England Journal of Medicine (2016)

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm.

by Gretarsdottir, S, Baas, AF, Thorleifsson, G, Holm, H, den Heijer, M, de Vries, JP, Kranendonk, SE, Zeebregts, CJ, van Sterkenburg, SM, Geelkerken, RH, van Rij, AM, Williams, MJ, Boll, AP, Kostic, JP, Jonasdottir, A, Walters, GB, Masson, G, Sulem, P, Saemundsdottir, J, Mouy, M, Magnusson, KP, Tromp, G, Elmore, JR, Sakalihasan, N, Limet, R, Defraigne, JO, Ferrell, RE, Ronkainen, A, Ruigrok, YM, Wijmenga, C, Grobbee, DE, Shah, SH, Granger, CB, Quyyumi, AA, Vaccarino, V, Patel, RS, Zafari, AM, Levey, AI, Austin, H, Girelli, D, Pignatti, PF, Olivieri, O, Martinelli, N, Malerba, G, Trabetti, E, Becker, LC, Becker, DM, Reilly, MP, Rader, DJ, Mueller, T, Dieplinger, B, Haltmayer, M, Urbonavicius, S, Lindblad, B, Gottsäter, A, Gaetani, E, Pola, R, Wells, P, Rodger, M, Forgie, M, Langlois, N, Corral, J, Vicente, V, Fontcuberta, J, España, F, Grarup, N, Jørgensen, T, Witte, DR, Hansen, T, Pedersen, O, Aben, KK, de Graaf, J, Holewijn, S, Folkersen, L, Franco-Cereceda, A, Eriksson, P, Collier, DA, Stefansson, H, Steinthorsdottir, V, Rafnar, T, Valdimarsson, EM, Magnadottir, HB, Sveinbjornsdottir, S, Olafsson, I, Magnusson, MK, Palmason, R, Haraldsdottir, V, Andersen, K, Onundarson, PT, Thorgeirsson, G, Kiemeney, LA, Powell, JT, Carey, DJ, Kuivaniemi, H, Lindholt, JS, Jones, GT, Kong, A, Blankensteijn, JD, Matthiasson, SE, Thorsteinsdottir, U, Stefansson, K
Published 2010

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

by Gretarsdottir S, Baas AF, Thorleifsson G, Holm H, den Heijer M, de Vries JP, Kranendonk SE, Zeebregts CJ, van Sterkenburg SM, Geelkerken RH, van Rij AM, Williams MJ, Boll AP, Kostic JP, Jonasdottir A, Walters GB, Masson G, Sulem P, Saemundsdottir J, Mouy M, Magnusson KP, Tromp G, Elmore JR, Sakalihasan N, Limet R, Defraigne JO, Ferrell RE, Ronkainen A, Ruigrok YM, Wijmenga C, Grobbee DE, Shah SH, Granger CB, Quyyumi AA, Vaccarino V, Patel RS, Zafari AM, Levey AI, Austin H, Becker LC, Becker DM, Reilly MP, Rader DJ, Mueller T, Dieplinger B, Haltmayer M, Urbonavicius S, Lindblad B, Gottsäter A, Gaetani E, Pola R, Wells P, Rodger M, Forgie M, Langlois N, Corral J, Vicente V, Fontcuberta J, España F, Grarup N, Jørgensen T, Witte DR, Hansen T, Pedersen O, Aben KK, de Graaf J, Holewijn S, Folkersen L, Franco Cereceda A, Eriksson P, Collier DA, Stefansson H, Steinthorsdottir V, Rafnar T, Valdimarsson EM, Magnadottir HB, Sveinbjornsdottir S, Olafsson I, Magnusson MK, Palmason R, Haraldsdottir V, Andersen K, Onundarson PT, Thorgeirsson G, Kiemeney LA, Powell JT, Carey DJ, Kuivaniemi H, Lindholt JS, Jones GT, Kong A, Blankensteijn JD, Matthiasson SE, Thorsteinsdottir U, Stefansson K., GIRELLI, Domenico, PIGNATTI, Pierfranco, OLIVIERI, Oliviero, MARTINELLI, Nicola, MALERBA, Giovanni, TRABETTI, Elisabetta
Published in Nature Genetics (2010)

Meta-analysis of exome array data identifies six novel genetic loci for lung function.

by Jackson, VE, Latourelle, JC, Wain, LV, Smith, AV, Grove, ML, Bartz, TM, Obeidat, M, Province, MA, Gao, W, Qaiser, B, Porteous, DJ, Cassano, PA, Ahluwalia, TS, Grarup, N, Li, J, Altmaier, E, Marten, J, Harris, SE, Manichaikul, A, Pottinger, TD, Li-Gao, R, Lind-Thomsen, A, Mahajan, A, Lahousse, L, Imboden, M, Teumer, A, Prins, B, Lyytikäinen, L-P, Eiriksdottir, G, Franceschini, N, Sitlani, CM, Brody, JA, Bossé, Y, Timens, W, Kraja, A, Loukola, A, Tang, W, Liu, Y, Bork-Jensen, J, Justesen, JM, Linneberg, A, Lange, LA, Rawal, R, Karrasch, S, Huffman, JE, Smith, BH, Davies, G, Burkart, KM, Mychaleckyj, JC, Bonten, TN, Enroth, S, Lind, L, Brusselle, GG, Kumar, A, Stubbe, B, Understanding Society Scientific Group, Kähönen, M, Wyss, AB, Psaty, BM, Heckbert, SR, Hao, K, Rantanen, T, Kritchevsky, SB, Lohman, K, Skaaby, T, Pisinger, C, Hansen, T, Schulz, H, Polasek, O, Campbell, A, Starr, JM, Rich, SS, Mook-Kanamori, DO, Johansson, Å, Ingelsson, E, Uitterlinden, AG, Weiss, S, Raitakari, OT, Gudnason, V, North, KE, Gharib, SA, Sin, DD, Taylor, KD, O'Connor, GT, Kaprio, J, Harris, TB, Pederson, O, Vestergaard, H, Wilson, JG, Strauch, K, Hayward, C, Kerr, S, Deary, IJ, Barr, RG, de Mutsert, R, Gyllensten, U, Morris, AP, Ikram, MA, Probst-Hensch, N, Gläser, S, Zeggini, E, Lehtimäki, T, Strachan, DP, Dupuis, J, Morrison, AC, Hall, IP, Tobin, MD, London, SJ
Published in Wellcome Open Research (2019)