Search Results

Genetic Loss of Sucrase-Isomaltase Function: Mechanisms, Implications, and Future Perspectives

by Senftleber NK, Ramne S, Moltke I, Jørgensen ME, Albrechtsen A, Hansen T, Andersen MK
Published 2023

Inuit in Greenland have significantly higher heritability for anthropometric traits

by Appel, E. R., Moltke, I., Jorgensen, M. E., Bjerregaard, P., Linneberg, A., Hansen, T., Grarup, N., Albrechtsen, A.
Published in European Journal of Human Genetics (2018)

Archaic adaptive introgression in TBX15/WARS2

by Racimo, F, Gokhman, D, Fumagalli, M, Ko, A, Hansen, T, Moltke, I, Albrechtsen, A, Carmel, L, Huerta-Sánchez, E, Nielsen, R
Published in Molecular Biology and Evolution (2016)

Archaic Adaptive Introgression in TBX15/WARS2

by Racimo, F, Gokhman, D, Fumagalli, M, Ko, A, Hansen, T, Moltke, I, Albrechtsen, A, Carmel, L, Huerta-Sanchez, E, Nielsen, R
Published 2017

Uncovering the genetic history of the present-day Greenlandic population.

by Moltke, I, Fumagalli, M, Korneliussen, TS, Crawford, JE, Bjerregaard, P, Jørgensen, ME, Grarup, N, Gulløv, HC, Linneberg, A, Pedersen, O, Hansen, T, Nielsen, R, Albrechtsen, A
Published 2015

The genetic history of Greenlandic-European contact.

by Waples, RK, Hauptmann, AL, Seiding, I, Jørsboe, E, Jørgensen, ME, Grarup, N, Andersen, MK, Larsen, CVL, Bjerregaard, P, Hellenthal, G, Hansen, T, Albrechtsen, A, Moltke, I
Published 2021

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

by Grarup, N., Moltke, I., Jorgensen, M. E., Bjerregaard, P., Treebak, J. T., Korneliussen, T. S., Andersen, M. A., Nielsen, T. S., Krarup, N. T., Linneberg, A., Wang, J., Pedersen, O., Nielsen, R., Albrechtsen, A., Hansen, T.
Published 2014

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

by Grarup, N, Moltke, I, Jorgensen, ME, Bjerregaard, P, Treebak, JT, Korneliussen, TS, Andersen, MA, Nielsen, TS, Krarup, NT, Linneberg, A, Wang, J, Pedersen, O, Nielsen, R, Albrechtsen, A, Hansen, T
Published 2014

Terminal Pleistocene Alaskan genome reveals first founding population of Native Americans

by Moreno-Mayar, JV, Potter, BA, Vinner, L, Steinrücken, M, Rasmussen, S, Terhorst, J, Kamm, JA, Albrechtsen, A, Malaspinas, A-S, Sikora, M, Reuther, JD, Irish, JD, Malhi, RS, Orlando, L, Song, YA, Nielsen, R, Meltzer, DJ, Willerslev, E
Published in Nature (2018)

Greenlandic Inuit show genetic signatures of diet and climate adaptation.

by Fumagalli, M, Moltke, I, Grarup, N, Racimo, F, Bjerregaard, P, Jørgensen, ME, Korneliussen, TS, Gerbault, P, Skotte, L, Linneberg, A, Christensen, C, Brandslund, I, Jørgensen, T, Huerta-Sánchez, E, Schmidt, EB, Pedersen, O, Hansen, T, Albrechtsen, A, Nielsen, R
Published 2015

Greenlandic Inuit show genetic signatures of diet and climate adaptation.

by Fumagalli, M, Moltke, I, Grarup, N, Racimo, F, Bjerregaard, P, Jørgensen, ME, Korneliussen, TS, Gerbault, P, Skotte, L, Linneberg, A, Christensen, C, Brandslund, I, Jørgensen, T, Huerta-Sánchez, E, Schmidt, EB, Pedersen, O, Hansen, T, Albrechtsen, A, Nielsen, R
Published in Science (2015)

Greenlandic Inuit show genetic signatures of diet and climate adaptation

by Fumagalli, M., Moltke, I., Grarup, N., Racimo, F., Bjerregaard, P., Jørgensen, M.E., Korneliussen, T.S., Gerbault, P., Skotte, L., Linneberg, A., Christensen, C., Brandslund, I., Jørgensen, T., Huerta-Sánchez, E., Schmidt, E.B., Pedersen, O., Hansen, T., Albrechtsen, A., Nielsen, R.
Published in Science (2015)

Terminal Pleistocene Alaskan genome reveals first founding population of Native Americans.

by Moreno-Mayar, J.V., Potter, B.A., Vinner, L., Steinrücken, M., Rasmussen, S., Terhorst, J., Kamm, J.A., Albrechtsen, A., Malaspinas, A.S., Sikora, M., Reuther, J.D., Irish, J.D., Malhi, R.S., Orlando, L., Song, Y.S., Nielsen, R., Meltzer, D.J., Willerslev, E.
Published in Nature (2018)

A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland

by Thuesen, A., Staeger, F., Kaci, A., Solheim, M., Aukrust, I., Jorsboe, E., Santander, C., Andersen , M., Li, Z., Gilly, A., Stinson, S., Gjesing, A., Bjerregaard, P., Pedersen, M., Larsen, C., Grarup, N., Jorgensen, M., Zeggini, E., Bjorkhaug, L., Njolstad, P., Albrechtsen, A., Moltke, I., Hansen, T.
Published in The Lancet Regional Health - Europe (2023)

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes.

by Moltke, I, Grarup, N, Jørgensen, ME, Bjerregaard, P, Treebak, JT, Fumagalli, M, Korneliussen, TS, Andersen, MA, Nielsen, TS, Krarup, NT, Gjesing, AP, Zierath, JR, Linneberg, A, Wu, X, Sun, G, Jin, X, Al-Aama, J, Wang, J, Borch-Johnsen, K, Pedersen, O, Nielsen, R, Albrechtsen, A, Hansen, T
Published 2014

Prehistoric genomes reveal the genetic foundation and cost of horse domestication.

by Schubert, M, Jónsson, H, Chang, D, Der Sarkissian, C, Ermini, L, Ginolhac, A, Albrechtsen, A, Dupanloup, I, Foucal, A, Petersen, B, Fumagalli, M, Raghavan, M, Seguin-Orlando, A, Korneliussen, TS, Velazquez, AM, Stenderup, J, Hoover, CA, Rubin, CJ, Alfarhan, AH, Alquraishi, SA, Al-Rasheid, KA, MacHugh, DE, Kalbfleisch, T, MacLeod, JN, Rubin, EM, Sicheritz-Ponten, T, Andersson, L, Hofreiter, M, Marques-Bonet, T, Gilbert, MT, Nielsen, R, Excoffier, L, Willerslev, E, Shapiro, B, Orlando, L
Published 2014

Tracking the origins of Yakutian horses and the genetic basis for their fast adaptation to subarctic environments.

by Librado, P, Der Sarkissian, C, Ermini, L, Schubert, M, Jónsson, H, Albrechtsen, A, Fumagalli, M, Yang, MA, Gamba, C, Seguin-Orlando, A, Mortensen, CD, Petersen, B, Hoover, CA, Lorente-Galdos, B, Nedoluzhko, A, Boulygina, E, Tsygankova, S, Neuditschko, M, Jagannathan, V, Thèves, C, Alfarhan, AH, Alquraishi, SA, Al-Rasheid, KA, Sicheritz-Ponten, T, Popov, R, Grigoriev, S, Alekseev, AN, Rubin, EM, McCue, M, Rieder, S, Leeb, T, Tikhonov, A, Crubézy, E, Slatkin, M, Marques-Bonet, T, Nielsen, R, Willerslev, E, Kantanen, J, Prokhortchouk, E, Orlando, L
Published in Proceedings of the National Academy of Sciences (2015)

Ancient human genome sequence of an extinct Palaeo-Eskimo

by Rasmussen, M., Li, Y., Lindgreen, S., Pedersen, J., Albrechtsen, A., Metspalu, M., Metspalu, E., Kivisild, T., Gupta, R., Bertalan, M., Nielsen, K., Gilbert, Thomas, Wang, Y., Raghavan, M., Campos, P., Kamp, H., Wilson, A., Gledhill, A., Tridico, S., Bunce, Michael, Lorenzen, E., Binladen, J., Guo, X., Zhao, J., Zhang, X., Zhang, H., Li, Z., Chen, M., Orlando, L., Kristiansen, K., Bak, M., Tommerup, N., Bendixen, C., Pierre, T., Grønnow, B., Meldgaard, M., Andreasen, C., Fedorova, S., Osipova, L., Higham, T., Ramsey, C., Hansen, T., Nielsen, F., Crawford, M., Brunak, S., Sicheritz-Ponten, T., Villems, R., Nielsen, R., Krogh, A., Wang, Jun, Willerslev, E., Moltke, I.
Published in Nature (2010)

Genomic data from an extinct Palaeo-Eskimo

by Rasmussen, M, Li, Y, Lindgreen, S, Pedersen, JS, Albrechtsen, A, Moltke, I, Metspalu, M, Metspalu, E, Kivisild, T, Gupta, R, Bertalan, M, Nielsen, K, Gilbert, MT, Wang, Y, Raghavan, M, Campos, PF, Kamp, HM, Wilson, AS, Gledhill, A, Tridico, S, Bunce, M, Lorenzen, ED, Binladen, J, Guo, X, Zhao, J, Zhang, X, Zhang, H, Li, Z, Chen, M, Orlando, L, Kristiansen, K, Bak, M, Tommerup, N, Bendixen, C, Pierre, TL, Gronnow, B, Meldgaard, M, Andreasen, C, Fedorova, SA, Osipova, LP, Higham, TF, Ramsey, CB, Hansen, TV, Nielsen, FC, Crawford, MH, Brunak, S, Sicheritz-Ponten, T, Villems, R, Nielsen, R, Krogh, A, Wang, J, Willerslev, E
Published 2011

Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse.

by Orlando, L, Ginolhac, A, Zhang, G, Froese, D, Albrechtsen, A, Stiller, M, Schubert, M, Cappellini, E, Petersen, B, Moltke, I, Johnson, PL, Fumagalli, M, Vilstrup, JT, Raghavan, M, Korneliussen, T, Malaspinas, AS, Vogt, J, Szklarczyk, D, Kelstrup, CD, Vinther, J, Dolocan, A, Stenderup, J, Velazquez, AM, Cahill, J, Rasmussen, M, Wang, X, Min, J, Zazula, GD, Seguin-Orlando, A, Mortensen, C, Magnussen, K, Thompson, JF, Weinstock, J, Gregersen, K, Røed, KH, Eisenmann, V, Rubin, CJ, Miller, DC, Antczak, DF, Bertelsen, MF, Brunak, S, Al-Rasheid, KA, Ryder, O, Andersson, L, Mundy, J, Krogh, A, Gilbert, MT, Kjær, K, Sicheritz-Ponten, T, Jensen, LJ, Olsen, JV, Hofreiter, M, Nielsen, R, Shapiro, B, Wang, J, Willerslev, E
Published 2013