Search Results

Assessing thyroid cancer risk using polygenic risk scores

by Liyanarachchi, Sandya, Gudmundsson, Julius, Ferkingstad, Egil, He, Huiling, Jonasson, Jon G, Tragante, Vinicius, Asselbergs, Folkert W, Xu, Li, Kiemeney, Lambertus A, Netea-Maier, Romana T, Mayordomo, Jose I, Plantinga, Theo S, Hjartarson, Hannes, Hrafnkelsson, Jon, Sturgis, Erich M, Brock, Pamela, Nabhan, Fadi, Thorleifsson, Gudmar, Ringel, Matthew D, Stefansson, Kari, de la Chapelle, Albert
Published 2020

Assessing thyroid cancer risk using polygenic risk scores

by Liyanarachchi, Sandya, Gudmundsson, Julius, Ferkingstad, Egil, He, Huiling, Jónasson, Jón Gunnlaugur, Tragante, Vinicius, Asselbergs, Folkert W., Xu, Li, Kiemeney, Lambertus A., Netea-Maier, Romana T., Mayordomo, Jose I., Plantinga, Theo S., Hjartarson, Hannes, Hrafnkelsson, Jón, Sturgis, Erich M., Brock, Pamela, Nabhan, Fadi, Thorleifsson, Gudmar, Ringel, Matthew D., Stefansson, Kari, de la Chapelle, Albert
Published in Proceedings of the National Academy of Sciences (2020)

Screening for Rare Coding Variants That Associate With the QTc Interval in Iceland

by Sveinbjornsson, Gardar, Benediktsdóttir, Bára Dís, Sigfússon, Gunnlaugur, Norland, Kristjan, Davidsson, Olafur B., Thorolfsdottir, Rosa B., Tragante, Vinicius, Arnadottir, Gudny A., Jensson, Brynjar O., Katrinardottir, Hildigunnur, Fridriksdottir, Run, Gudmundsdottir, Hallbera, Ægisdóttir, Hildur Margrét, Fridriksson, Brynjar, Thorgeirsson, Gudmundur, Magnússon, Viðar, Oddsson, Asmundur, Sulem, Patrick, Gudbjartsson, Daniel F., Holm, Hilma, Arnar, Davíð Ottó, Stefánsson, Kári
Published in Journal of the American Heart Association (2023)

Screening for Rare Coding Variants That Associate With the QTc Interval in Iceland

by Sveinbjornsson, Gardar, Benediktsdottir, Bara D., Sigfusson, Gunnlaugur, Norland, Kristjan, Davidsson, Olafur B., Thorolfsdottir, Rosa B., Tragante, Vinicius, Arnadottir, Gudny A., Jensson, Brynjar O., Katrinardottir, Hildigunnur, Fridriksdottir, Run, Gudmundsdottir, Hallbera, Aegisdottir, Hildur M., Fridriksson, Brynjar, Thorgeirsson, Gudmundur, Magnusson, Vidar, Oddsson, Asmundur, Sulem, Patrick, Gudbjartsson, Daniel F., Holm, Hilma, Arnar, David O., Stefansson, Kari
Published in Journal of the American Heart Association (2023)

Variants in NKX2-5 and FLNC Cause Dilated Cardiomyopathy and Sudden Cardiac Death.

by Sveinbjornsson, Gardar, Olafsdottir, Eva F, Thorolfsdottir, Rosa B, Davidsson, Olafur B, Helgadottir, Anna, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Bjornsson, Eythor, Jensson, Brynjar O, Arnadottir, Gudny A, Kristinsdottir, Hallfridur, Stephensen, Sigurdur S, Oskarsson, Gylfi, Gudbjartsson, Tomas, Sigurdsson, Emil L, Andersen, Karl, Danielsen, Ragnar, Arnar, David O, Jonsdottir, Ingileif, Thorsteinsdottir, Unnur, Sulem, Patrick, Thorgeirsson, Gudmundur, Gudbjartsson, Daniel F, Holm, Hilma, Stefansson, Kari
Published in Circulation: Genomic and Precision Medicine (2018)

Effects of a 5-lipoxygenase-activating protein inhibitor on biomarkers associated with risk of myocardial infarction: a randomized trial

by Hakonarson, Hakon, Thorvaldsson, Sverrir, Helgadottir, Anna, Gudbjartsson, Daniel, Zink, Florian, Andresdottir, Margret, Manolescu, Andrei, Arnar, David O, Andersen, Karl, Sigurdsson, Axel, Thorgeirsson, Gestur, Jonsson, Asgeir, Agnarsson, Uggi, Bjornsdottir, Halldora, Gottskalksson, Gizur, Einarsson, Atli, Gudmundsdottir, Hrefna, Adalsteinsdottir, Asdis E, Gudmundsson, Kolbeinn, Kristjansson, Kristleifur, Hardarson, Thordur, Kristinsson, Arni, Topol, Eric J, Gulcher, Jeffrey, Kong, Augustine, Gurney, Mark, Thorgeirsson, Gudmundur, Stefansson, Kari
Published in JAMA (2009)

Variant of TREM2 associated with the risk of Alzheimer's disease.

by Jonsson, Thorlakur, Stefansson, Hreinn, Steinberg, Stacy, Jonsdottir, Ingileif, Jonsson, Palmi V, Snaedal, Jon, Bjornsson, Sigurbjorn, Huttenlocher, Johanna, Levey, Allan I, Lah, James J, Rujescu, Dan, Hampel, Harald, Giegling, Ina, Andreassen, Ole A, Engedal, Knut, Ulstein, Ingun, Djurovic, Srdjan, Ibrahim-Verbaas, Carla, Hofman, Albert, Ikram, M Arfan, van Duijn, Cornelia M, Thorsteinsdottir, Unnur, Kong, Augustine, Stefansson, Kari
Published in New England Journal of Medicine (2013)

Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density.

by Thorleifsson, Gudmar, Holm, Hilma, Edvardsson, Vidar, Walters, G Bragi, Styrkarsdottir, Unnur, Gudbjartsson, Daniel F, Sulem, Patrick, Halldorsson, Bjarni V, de Vegt, Femmie, d'Ancona, Frank C H, den Heijer, Martin, Franzson, Leifur, Christiansen, Claus, Alexandersen, Peter, Rafnar, Thorunn, Kristjansson, Kristleifur, Sigurdsson, Gunnar, Kiemeney, Lambertus A, Bodvarsson, Magnus, Indridason, Olafur S, Palsson, Runolfur, Kong, Augustine, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature Genetics (2009)

Association between microdeletion and microduplication at 16p11.2 and autism

by Weiss, Lauren A., Shen, Yiping, Korn, Joshua M., Arking, Dan E., Miller, David T., Fossdal, Ragnheidur, Saemundsen, Evald, Stefansson, Hreinn, Ferreira, Manuel A.R., Green, Todd, Platt, Orah S., Ruderfer, Douglas M., Walsh, Christopher A., Altshuler, David, Chakravarti, Aravinda, Tanzi, Rudolph E., Stefansson, Kari, Santangelo, Susan L., Gusella, James F., Sklar, Pamela, Wu, Bai-Lin, Daly, Mark J.
Published in New England Journal of Medicine (2008)

No Association Between a Common Single Nucleotide Polymorphism, rs4141463, in the MACROD2 Gene and Autism Spectrum Disorder

by Curran, Sarah, Bolton, Patrick, Rozsnyai, Kinga, Chiocchetti, Andreas, Klauck, Sabine M., Duketis, Eftichia, Poustka, Fritz, Schlitt, Sabine, Freitag, Christine M., Lee, Irene, Muglia, Pierandrea, Poot, Martin, Staal, Wouter, de Jonge, Maretha V., Ophoff, Roel A., Lewis, Cathryn, Skuse, David, Mandy, Will, Vassos, Evangelos, Fossdal, Ragnheidur, Magnusson, Pall, Hreidarsson, Stefan, Saemundsen, Evald, Stefansson, Hreinn, Stefansson, Kari, Collier, David
Published in American Journal of Medical Genetics Part B: Neuropsychiatric Genetics (2011)

Genetic determinants of hair, eye and skin pigmentation in Europeans

by Sulem, Patrick, Gudbjartsson, Daniel F, Stacey, Simon N, Helgason, Agnar, Rafnar, Thorunn, Magnusson, Kristinn P, Manolescu, Andrei, Karason, Ari, Palsson, Arnar, Thorleifsson, Gudmar, Jakobsdottir, Margret, Steinberg, Stacy, Pálsson, Snaebjörn, Jonasson, Fridbert, Sigurgeirsson, Bardur, Thorisdottir, Kristin, Ragnarsson, Rafn, Benediktsdottir, Kristrun R, Aben, Katja K, Kiemeney, Lambertus A, Olafsson, Jon H, Gulcher, Jeffrey, Kong, Augie, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature Genetics (2008)

No association between a common single nucleotide polymorphism, rs4141463, in the MACROD2 gene and autism spectrum disorder.

by Curran, Sarah, Bolton, Patrick, Rozsnyai, Kinga, Chiocchetti, Andreas, Klauck, Sabine M, Duketis, Eftichia, Poustka, Fritz, Schlitt, Sabine, Freitag, Christine M, Lee, Irene, Muglia, Pierandrea, Poot, Martin, Staal, Wouter, de Jonge, Maretha V, Ophoff, Roel A, Lewis, Cathryn, Skuse, David, Mandy, Will, Vassos, Evangelos, Fossdal, Ragnheidur, Magnusson, Páll, Hreidarsson, Stefan, Saemundsen, Evald, Stefansson, Hreinn, Stefansson, Kari, Collier, David
Published in American Journal of Medical Genetics Part B: Neuropsychiatric Genetics (2012)

No association between a common single nucleotide polymorphism, rs4141463, in the MACROD2 gene and autism spectrum disorder

by Curran, Sarah, Bolton, Patrick, Rozsnyai, Kinga, Chiocchetti, Andreas, Klauck, Sabine M., Duketis, Eftichia, Poustka, Fritz, Schlitt, Sabine, Freitag, Christine M., Lee, Irene, Muglia, Pierandrea, Poot, Martin, Staal, Wouter, de Jonge, Maretha V., Ophoff, Roel A., Lewis, Cathryn, Skuse, David, Mandy, Will, Vassos, Evangelos, Fossdal, Ragnheidur, Magnusson, Páll, Hreidarsson, Stefan, Saemundsen, Evald, Stefansson, Hreinn, Stefansson, Kari, Collier, David
Published in American Journal of Medical Genetics Part B: Neuropsychiatric Genetics (2011)

Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density

by Thorleifsson, Gudmar, Holm, Hilma, Edvardsson, Vidar, Walters, G. Bragi, Styrkarsdottir, Unnur, Gudbjartsson, Daniel F., Sulem, Patrick, Halldorsson, Bjarni V., De Vegt, Femmie, D'Ancona, Frank C.H., Den Heijer, Martin, Franzson, Leifur, Christiansen, Claus, Alexandersen, Peter, Rafnar, Thorunn, Kristjansson, Kristleifur, Sigurdsson, Gunnar, Kiemeney, Lambertus A., Bodvarsson, Magnus, Indridason, Olafur S., Palsson, Runolfur, Kong, Augustine, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature Genetics (2009)

Comprehensive population-wide analysis of Lynch syndrome in Iceland reveals founder mutations in MSH6 and PMS2

by Haraldsdottir, Sigurdis, Rafnar, Thorunn, Frankel, Wendy L., Einarsdottir, Sylvia, Sigurdsson, Asgeir, Hampel, Heather, Snaebjornsson, Petur, Masson, Gisli, Weng, Daniel, Arngrimsson, Reynir, Kehr, Birte, Yilmaz, Ahmet, Haraldsson, Stefan, Sulem, Patrick, Stefansson, Tryggvi, Shields, Peter G., Sigurdsson, Fridbjorn, Bekaii-Saab, Tanios, Moller, Pall H., Steinarsdottir, Margret, Alexiusdottir, Kristin, Hitchins, Megan, Pritchard, Colin C., de la Chapelle, Albert, Jonasson, Jon G., Goldberg, Richard M., Stefansson, Kari
Published in Nature Communications (2017)

Comprehensive population-wide analysis of Lynch syndrome in Iceland reveals founder mutations in MSH6 and PMS2.

by Haraldsdottir, Sigurdis, Rafnar, Thorunn, Frankel, Wendy L, Einarsdottir, Sylvia, Sigurdsson, Asgeir, Hampel, Heather, Snaebjornsson, Petur, Masson, Gisli, Weng, Daniel, Arngrimsson, Reynir, Kehr, Birte, Yilmaz, Ahmet, Haraldsson, Stefan, Sulem, Patrick, Stefansson, Tryggvi, Shields, Peter G, Sigurdsson, Fridbjorn, Bekaii-Saab, Tanios, Moller, Pall H, Steinarsdottir, Margret, Alexiusdottir, Kristin, Hitchins, Megan, Pritchard, Colin C, de la Chapelle, Albert, Jonasson, Jon G, Goldberg, Richard M, Stefansson, Kari
Published in Nature Communications (2017)

Comprehensive population-wide analysis of Lynch syndrome in Iceland reveals founder mutations in MSH6 and PMS2

by Haraldsdottir, Sigurdis, Rafnar, Thorunn, Frankel, Wendy L., Einarsdottir, Sylvia, Sigurdsson, Asgeir, Hampel, Heather, Snaebjornsson, Petur, Masson, Gisli, Weng, Daniel, Arngrimsson, Reynir, Kehr, Birte, Yilmaz, Ahmet, Haraldsson, Stefan, Sulem, Patrick, Stefansson, Tryggvi, Shields, Peter G., Sigurdsson, Fridbjorn, Bekaii-Saab, Tanios, Moller, Pall H., Steinarsdottir, Margret, Alexiusdottir, Kristin, Hitchins, Megan, Pritchard, Colin C., de la Chapelle, Albert, Jonasson, Jon G., Goldberg, Richard M., Stefansson, Kari
Published in Nature Communications (2017)

Two newly identified genetic determinants of pigmentation in Europeans.

by Sulem, Patrick, Gudbjartsson, Daniel F, Stacey, Simon N, Helgason, Agnar, Rafnar, Thorunn, Jakobsdottir, Margret, Steinberg, Stacy, Gudjonsson, Sigurjon A, Palsson, Arnar, Thorleifsson, Gudmar, Pálsson, Snaebjörn, Sigurgeirsson, Bardur, Thorisdottir, Kristin, Ragnarsson, Rafn, Benediktsdottir, Kristrun R, Aben, Katja K, Vermeulen, Sita H, Goldstein, Alisa M, Tucker, Margaret A, Kiemeney, Lambertus A, Olafsson, Jon H, Gulcher, Jeffrey, Kong, Augustine, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature Genetics (2008)

The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke.

by Helgadottir, Anna, Manolescu, Andrei, Thorleifsson, Gudmar, Gretarsdottir, Solveig, Jonsdottir, Helga, Thorsteinsdottir, Unnur, Samani, Nilesh J, Gudmundsson, Gudmundur, Grant, Struan F A, Thorgeirsson, Gudmundur, Sveinbjornsdottir, Sigurlaug, Valdimarsson, Einar M, Matthiasson, Stefan E, Johannsson, Halldor, Gudmundsdottir, Olof, Gurney, Mark E, Sainz, Jesus, Thorhallsdottir, Margret, Andresdottir, Margret, Frigge, Michael L, Topol, Eric J, Kong, Augustine, Gudnason, Vilmundur, Hakonarson, Hakon, Gulcher, Jeffrey R, Stefansson, Kari
Published in Nature Genetics (2009)

Sequence variants in the PTCH1 gene associate with spine bone mineral density and osteoporotic fractures.

by Styrkarsdottir, Unnur, Thorleifsson, Gudmar, Gudjonsson, Sigurjon A, Sigurdsson, Asgeir, Center, Jacqueline R, Lee, Seung Hun, Nguyen, Tuan V, Kwok, Timothy C Y, Lee, Jenny S W, Ho, Suzanne C, Woo, Jean, Leung, Ping-C, Kim, Beom-Jun, Rafnar, Thorunn, Kiemeney, Lambertus A, Ingvarsson, Thorvaldur, Koh, Jung-Min, Tang, Nelson L S, Eisman, John A, Christiansen, Claus, Sigurdsson, Gunnar, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature Communications (2016)