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1by Diego Benítez, Andrea Medeiros, Lucía Fiestas, Esteban A Panozzo-Zenere, Franziska Maiwald, Kyriakos C Prousis, Marina Roussaki, Theodora Calogeropoulou, Anastasia Detsi, Timo Jaeger, Jonas Šarlauskas, Lucíja Peterlin Mašič, Conrad Kunick, Guillermo R Labadie, Leopold Flohé, Marcelo A Comini“... intra-assay reproducibility. Several novel chemical scaffolds were identified as low μM and selective...”
Published in PLOS Neglected Tropical Diseases (2016)
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2by Jair L Siqueira-Neto, Ok-Ryul Song, Hyunrim Oh, Jeong-Hun Sohn, Gyongseon Yang, Jiyoun Nam, Jiyeon Jang, Jonathan Cechetto, Chang Bok Lee, Seunghyun Moon, Auguste Genovesio, Eric Chatelain, Thierry Christophe, Lucio H Freitas-JuniorGet access
Published in PLoS Neglected Tropical Diseases (2010)
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3by V Haridas, Kullampalayam Shanmugam Rajgokul, Sandhya Sadanandan, Tanvi Agrawal, Vats Sharvani, M V S Gopalakrishna, M B Bijesh, Kanhaiya Lal Kumawat, Anirban Basu, Guruprasad R Medigeshi“... identified 3,7-diazabicyclo[3.3.1]nonane, commonly called bispidine, as a privileged scaffold to synthesize...”
Published in PLoS Neglected Tropical Diseases (2013)
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4by Diana Tegazzini, Juan Cantizani, Imanol Peña, Julio Martín, Jose M Coterón“... to their minimal chemical scaffold. Comparison of the results showed a complete correlation between the chemical...”
Published in PLOS Neglected Tropical Diseases (2017)
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5by Tony Taldone, Victoria Gillan, Weilin Sun, Anna Rodina, Pallav Patel, Kirsty Maitland, Kerry O'Neill, Gabriela Chiosis, Eileen Devaney“... that compete with geldanamycin for binding to Hsp90, including members of the synthetic purine-scaffold series...”
Published in PLoS Neglected Tropical Diseases (2010)
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6by Leandro A A Avelar, Cristian D Camilo, Sérgio de Albuquerque, William B Fernandes, Cristiana Gonçalez, Peter W Kenny, Andrei Leitão, James H McKerrow, Carlos A Montanari, Erika V Meñaca Orozco, Jean F R Ribeiro, Josmar R Rocha, Fabiana Rosini, Marta E Saidel“...A series of compounds based on the dipeptidyl nitrile scaffold were synthesized and assayed...”
Published in PLOS Neglected Tropical Diseases (2015)
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7by John D Chan, Prince N Agbedanu, Thomas Grab, Mostafa Zamanian, Peter I Dosa, Timothy A Day, Jonathan S Marchant“... the ergot alkaloid scaffold as a promising structural framework for designing potent agents targeting...”
Published in PLOS Neglected Tropical Diseases (2015)
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8by Punita Juneja, Jewelna Osei-Poku, Yung S Ho, Cristina V Ariani, William J Palmer, Arnab Pain, Francis M Jiggins“... has resulted in the genome being poorly assembled - there are 4,758 scaffolds, few of which have been...”
Published in PLoS Neglected Tropical Diseases (2014)
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9by Lorenzo Turcano, Theo Battista, Esther Torrente De Haro, Antonino Missineo, Cristina Alli, Giacomo Paonessa, Gianni Colotti, Steven Harper, Annarita Fiorillo, Andrea Ilari, Alberto Bresciani“... scaffold is known to be suitable for brain active compounds in humans thus representing an attractive...”
Published in PLOS Neglected Tropical Diseases (2020)
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10by Chiung-Kuang Chen, Patricia S Doyle, Liudmila V Yermalitskaya, Zachary B Mackey, Kenny K H Ang, James H McKerrow, Larissa M Podust“... carrying this scaffold were determined by high-resolution co-crystal structures with CYP51(Mt). Subsequent...”
Published in PLoS Neglected Tropical Diseases (2009)
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11by Andrew P Jackson, Mandy Sanders, Andrew Berry, Jacqueline McQuillan, Martin A Aslett, Michael A Quail, Bridget Chukualim, Paul Capewell, Annette MacLeod, Sara E Melville, Wendy Gibson, J David Barry, Matthew Berriman, Christiane Hertz-Fowler“... should therefore be an effective scaffold for any T. brucei genome sequence data. As VSG repertoire...”
Published in PLoS Neglected Tropical Diseases (2010)
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12by Gregory J Crowther, Michael L Booker, Min He, Ting Li, Sylvine Raverdy, Jacopo F Novelli, Panqing He, Natalie R G Dale, Amy M Fife, Robert H Barker, Martin L Kramer, Wesley C Van Voorhis, Clotilde K S Carlow, Ming-Wei Wang“... singleton hits rather than members of a common scaffold. Thus, despite the other appealing properties...”
Published in PLoS Neglected Tropical Diseases (2014)
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13by Fang Luo, Mingbo Yin, Xiaojin Mo, Chengsong Sun, Qunfeng Wu, Bingkuan Zhu, Manyu Xiang, Jipeng Wang, Yi Wang, Jian Li, Ting Zhang, Bin Xu, Huajun Zheng, Zheng Feng, Wei Hu“... assembly is approximately 370.5 Mb, with contig and scaffold N50 length of 871.9 kb and 1.09 Mb...”
Published in PLOS Neglected Tropical Diseases (2019)
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14by Harry F Williams, Ben A Mellows, Robert Mitchell, Peggy Sfyri, Harry J Layfield, Maryam Salamah, Rajendran Vaiyapuri, Henry Collins-Hooper, Andrew B Bicknell, Antonios Matsakas, Ketan Patel, Sakthivel Vaiyapuri“... analyses revealed that CAMP significantly damages skeletal muscles by attacking the collagen scaffold...”
Published in PLOS Neglected Tropical Diseases (2019)
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15by Andres Garcia-Campos, Alessandra Ravidà, D Linh Nguyen, Krystyna Cwiklinski, John P Dalton, Cornelis H Hokke, Sandra O'Neill, Grace Mulcahy“... established that cathepsin B1 (FhCB1) on position N80, and FhCL3 (BN1106_s10139B000014, scaffold10139...”
Published in PLOS Neglected Tropical Diseases (2016)
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16by Li Li, Bing Chen, Hongbin Yan, Yannan Zhao, Zhongzi Lou, Jianqiu Li, Baoquan Fu, Xingquan Zhu, Donald P McManus, Jianwu Dai, Wanzhong Jia“... and mesenchymal stem cells using a collagen scaffold to study the development of Echinococcus multilocularis...”
Published in PLOS Neglected Tropical Diseases (2018)
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17by Deu John M Cruz, Rafaela M Bonotto, Rafael G B Gomes, Camila T da Silva, Juliana B Taniguchi, Joo Hwan No, Benoit Lombardot, Olivier Schwartz, Michael A E Hansen, Lucio H Freitas-Junior“... as primary hits. Four compounds having a benzofuran core scaffold (CND0335, CND0364, CND0366 and CND0415...”
Published in PLoS Neglected Tropical Diseases (2013)
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18by Emma Webster, Allan Hall (Yuwaallaraay/Gamilaroi), Yvonne Hill (Wiradjuri), Cecil See (Wiradjuri), Eunice Simons, Rachael Havrlant, Regina Osten“... in Aboriginal health. Learning about cultural processes provided scaffolding to show how services and models...”
Published in Australian and New Zealand Journal of Public Health (2022)
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19by Antonio C B Burtoloso, Sérgio de Albuquerque, Mark Furber, Juliana C Gomes, Cristiana Gonçalez, Peter W Kenny, Andrei Leitão, Carlos A Montanari, José Carlos Quilles, Jean F R Ribeiro, Josmar R Rocha“... scaffolds known to be associated with cathepsin K inhibition. The two compounds showing the greatest potency...”
Published in PLOS Neglected Tropical Diseases (2017)
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20by Wilson Lim, Bertrand Nyuykonge, Kimberly Eadie, Mickey Konings, Juli Smeets, Ahmed Fahal, Alexandro Bonifaz, Matthew Todd, Benjamin Perry, Kirandeep Samby, Jeremy Burrows, Annelies Verbon, Wendy van de Sande“... candidates to explore in mycetoma treatment and to also serve as scaffolds for medicinal chemistry...”
Published in PLOS Neglected Tropical Diseases (2022)
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