Search Results

Genome-wide association meta-analysis yields 20 loci associated with gallstone disease.

by Ferkingstad, Egil, Oddsson, Asmundur, Gretarsdottir, Solveig, Benonisdottir, Stefania, Thorleifsson, Gudmar, Deaton, Aimee M, Jonsson, Stefan, Stefansson, Olafur A, Norddahl, Gudmundur L, Zink, Florian, Arnadottir, Gudny A, Gunnarsson, Bjarni, Halldorsson, Gisli H, Helgadottir, Anna, Jensson, Brynjar O, Kristjansson, Ragnar P, Sveinbjornsson, Gardar, Sverrisson, David A, Masson, Gisli, Olafsson, Isleifur, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Holm, Hilma, Jonsdottir, Ingileif, Olafsson, Sigurdur, Steingrimsdottir, Thora, Rafnar, Thorunn, Bjornsson, Einar S, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F, Sulem, Patrick, Stefansson, Kari
Published in Nature Communications (2018)

Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA.

by Gudmundsson, Julius, Sigurdsson, Jon K, Stefansdottir, Lilja, Agnarsson, Bjarni A, Isaksson, Helgi J, Stefansson, Olafur A, Gudjonsson, Sigurjon A, Gudbjartsson, Daniel F, Masson, Gisli, Frigge, Michael L, Stacey, Simon N, Sulem, Patrick, Halldorsson, Gisli H, Tragante, Vinicius, Holm, Hilma, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Olafsson, Isleifur, Jonsson, Thorvaldur, Jonsson, Eirikur, Barkardottir, Rosa B, Hilmarsson, Rafn, Asselbergs, Folkert W, Geirsson, Gudmundur, Thorsteinsdottir, Unnur, Rafnar, Thorunn, Thorleifsson, Gudmar, Stefansson, Kari
Published in Nature Communications (2018)

A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis.

by Kristjansson, Ragnar P, Benonisdottir, Stefania, Davidsson, Olafur B, Oddsson, Asmundur, Tragante, Vinicius, Sigurdsson, Jon K, Stefansdottir, Lilja, Jonsson, Stefan, Jensson, Brynjar O, Arthur, Joseph G, Arnadottir, Gudny A, Sulem, Gerald, Halldorsson, Bjarni V, Gunnarsson, Bjarni, Halldorsson, Gisli H, Stefansson, Olafur A, Oskarsson, Gudjon R, Deaton, Aimee M, Olafsson, Isleifur, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Onundarson, Pall T, Gislason, David, Gislason, Thorarinn, Ludviksson, Bjorn R, Ludviksdottir, Dora, Olafsdottir, Thorunn A, Rafnar, Thorunn, Masson, Gisli, Zink, Florian, Bjornsdottir, Gyda, Magnusson, Olafur Th, Bjornsdottir, Unnur S, Thorleifsson, Gudmar, Norddahl, Gudmundur L, Gudbjartsson, Daniel F, Thorsteinsdottir, Unnur, Jonsdottir, Ingileif, Sulem, Patrick, Stefansson, Kari
Published in Nature Genetics (2019)

Predicted loss and gain of function mutations in ACO1 are associated with erythropoiesis.

by Oskarsson, Gudjon R, Oddsson, Asmundur, Magnusson, Magnus K, Kristjansson, Ragnar P, Halldorsson, Gisli H, Ferkingstad, Egil, Zink, Florian, Helgadottir, Anna, Ivarsdottir, Erna V, Arnadottir, Gudny A, Jensson, Brynjar O, Katrinardottir, Hildigunnur, Sveinbjornsson, Gardar, Kristinsdottir, Anna M, Lee, Amy L, Saemundsdottir, Jona, Stefansdottir, Lilja, Sigurdsson, Jon K, Davidsson, Olafur B, Benonisdottir, Stefania, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Jonsson, Stefan, Gudmundsson, Reynir L, Asselbergs, Folkert W, Tragante, Vinicius, Gunnarsson, Bjarni, Masson, Gisli, Thorleifsson, Gudmar, Rafnar, Thorunn, Holm, Hilma, Olafsson, Isleifur, Onundarson, Pall T, Gudbjartsson, Daniel F, Norddahl, Gudmundur L, Thorsteinsdottir, Unnur, Sulem, Patrick, Stefansson, Kari
Published in Communications Biology (2020)

Rare SCARB1 mutations associate with high-density lipoprotein cholesterol but not with coronary artery disease

by Helgadottir, Anna, Sulem, Patrick, Thorgeirsson, Gudmundur, Gretarsdottir, Solveig, Thorleifsson, Gudmar, Jensson, Brynjar Ö, Arnadottir, Gudny A, Olafsson, Isleifur, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F, Holm, Hilma, Stefansson, Kari
Published in European Heart Journal (2018)

Identification of low-frequency variants associated with gout and serum uric acid levels.

by Sulem, Patrick, Gudbjartsson, Daniel F, Walters, G Bragi, Helgadottir, Hafdis T, Helgason, Agnar, Gudjonsson, Sigurjon A, Zanon, Carlo, Besenbacher, Soren, Bjornsdottir, Gyda, Magnusson, Olafur T, Magnusson, Gisli, Hjartarson, Eirikur, Saemundsdottir, Jona, Gylfason, Arnaldur, Jonasdottir, Adalbjorg, Holm, Hilma, Karason, Ari, Rafnar, Thorunn, Stefansson, Hreinn, Andreassen, Ole A, Pedersen, Jesper H, Pack, Allan I, de Visser, Marieke C H, Kiemeney, Lambertus A, Geirsson, Arni J, Eyjolfsson, Gudmundur I, Olafsson, Isleifur, Kong, Augustine, Masson, Gisli, Jonsson, Helgi, Thorsteinsdottir, Unnur, Jonsdottir, Ingileif, Stefansson, Kari
Published in Nature Genetics (2012)

Discovery of common variants associated with low TSH levels and thyroid cancer risk.

by Gudmundsson, Julius, Sulem, Patrick, Gudbjartsson, Daniel F, Jonasson, Jon G, Masson, Gisli, He, Huiling, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Stacey, Simon N, Johannsdottir, Hrefna, Helgadottir, Hafdis Th, Li, Wei, Nagy, Rebecca, Ringel, Matthew D, Kloos, Richard T, de Visser, Marieke C H, Plantinga, Theo S, den Heijer, Martin, Aguillo, Esperanza, Panadero, Angeles, Prats, Enrique, Garcia-Castaño, Almudena, De Juan, Ana, Rivera, Fernando, Walters, G Bragi, Bjarnason, Hjordis, Tryggvadottir, Laufey, Eyjolfsson, Gudmundur I, Bjornsdottir, Unnur S, Holm, Hilma, Olafsson, Isleifur, Kristjansson, Kristleifur, Kristvinsson, Hoskuldur, Magnusson, Olafur T, Thorleifsson, Gudmar, Gulcher, Jeffrey R, Kong, Augustine, Kiemeney, Lambertus A L M, Jonsson, Thorvaldur, Hjartarson, Hannes, Mayordomo, Jose I, Netea-Maier, Romana T, de la Chapelle, Albert, Hrafnkelsson, Jon, Thorsteinsdottir, Unnur, Rafnar, Thorunn, Stefansson, Kari
Published in Nature Genetics (2013)

Eighty-eight variants highlight the role of T cell regulation and airway remodeling in asthma pathogenesis

by Ólafsdóttir, Þórunn Ásta, Theódórs, Fannar, Bjarnadóttir, Kristbjörg, Björnsdóttir, Unnur Steina, Agustsdottir, Arna B., Stefánsson, Ólafur A., Ivarsdottir, Erna, Sigurðsson, Jón K., Benónísdóttir, Stefanía, Eyjólfsson, Guðmundur I., Gíslason, Davíð, Gislason, Thorarinn, Guðmundsdóttir, Steinunn, Gylfason, Arnaldur, Halldórsson, Bjarni, Halldorsson, Gisli, Júlíusdóttir, Þórhildur, Kristinsdottir, Anna M., Lúðvíksdóttir, Dóra, Ludviksson, Bjorn, Másson, Gísli, Norland, Kristjan, Onundarson, Pall, Olafsson, Isleifur, Sigurdardottir, Olof, Stefánsdóttir, Lilja, Sveinbjörnsson, Garðar, Tragante do O, Vinicius, Gudbjartsson, Daniel, Þorleifsson, Guðmar, sulem, patrick, Thorsteinsdottir, Unnur, Norddahl, Guðmundur L., Jonsdottir, Ingileif, Stefansson, Kari
Published in Nature Communications (2020)

Variants at the Interleukin 1 Gene Locus and Pericarditis

by Thorolfsdottir, Rosa B., Jonsdottir, Andrea B., Sveinbjornsson, Gardar, Aegisdottir, Hildur M., Oddsson, Asmundur, Stefansson, Olafur A., Halldorsson, Gisli H., Saevarsdottir, Saedis, Thorleifsson, Gudmar, Stefansdottir, Lilja, Pedersen, Ole B., Sørensen, Erik, Ghouse, Jonas, Raja, Anna Axelsson, Zheng, Chaoqun, Silajdzija, Elvira, Rand, Søren Albertsen, Erikstrup, Christian, Ullum, Henrik, Mikkelsen, Christina, Banasik, Karina, Brunak, Søren, Ivarsdottir, Erna V., Sigurdsson, Asgeir, Beyter, Doruk, Sturluson, Arni, Einarsson, Hafsteinn, Tragante, Vinicius, Helgason, Hannes, Lund, Sigrun H., Halldorsson, Bjarni V., Sigurpalsdottir, Brynja D., Olafsson, Isleifur, Arnar, David O., Thorgeirsson, Gudmundur, Knowlton, Kirk U., Nadauld, Lincoln D., Gretarsdottir, Solveig, Helgadottir, Anna, Ostrowski, Sisse R., Gudbjartssson, Daniel F., Jonsdottir, Ingileif, Bundgaard, Henning, Holm, Hilma, Sulem, Patrick, Stefansson, Kari, Banasik, Karina, Bay, Jakob, Boldsen, Jens K., Brodersen, Thorsten
Published in JAMA Cardiology (2024)

Genetic correction of PSA values using sequence variants associated with PSA levels

by Gudmundsson, Julius, Besenbacher, Soren, Sulem, Patrick, Gudbjartsson, Daniel F, Olafsson, Isleifur, Arinbjarnarson, Sturla, Agnarsson, Bjarni A, Benediktsdottir, Kristrun R, Isaksson, Helgi J, Kostic, Jelena P, Gudjonsson, Sigurjon A, Stacey, Simon N, Gylfason, Arnaldur, Sigurdsson, Asgeir, Holm, Hilma, Bjornsdottir, Unnur S, Eyjolfsson, Gudmundur I, Navarrete, Sebastian, Fuertes, Fernando, Garcia-Prats, Maria D, Polo, Eduardo, Checherita, Ionel A, Jinga, Mariana, Badea, Paula, Aben, Katja K, Schalken, Jack A, van Oort, Inge M, Sweep, Fred C, Helfand, Brian T, Davis, Michael, Donovan, Jenny L, Hamdy, Freddie C, Kristjansson, Kristleifur, Gulcher, Jeffrey R, Masson, Gisli, Kong, Augustine, Catalona, William J, Mayordomo, Jose I, Geirsson, Gudmundur, Einarsson, Gudmundur V, Barkardottir, Rosa B, Jonsson, Eirikur, Jinga, Viorel, Mates, Dana, Kiemeney, Lambertus A, Neal, David E, Thorsteinsdottir, Unnur, Rafnar, Thorunn, Stefansson, Kari
Published in Science Translational Medicine (2011)

Variants at the Interleukin 1 Gene Locus and Pericarditis

by Thorolfsdottir, Rosa B., Jonsdottir, Andrea B., Sveinbjornsson, Gardar, Aegisdottir, Hildur M., Oddsson, Asmundur, Stefansson, Olafur A., Halldorsson, Gisli H., Saevarsdottir, Saedis, Thorleifsson, Gudmar, Stefansdottir, Lilja, Pedersen, Ole B., Sørensen, Erik, Ghouse, Jonas, Raja, Anna Axelsson, Zheng, Chaoqun, Silajdzija, Elvira, Rand, Søren Albertsen, Erikstrup, Christian, Ullum, Henrik, Mikkelsen, Christina, Banasik, Karina, Brunak, Søren, Ivarsdottir, Erna V., Sigurdsson, Asgeir, Beyter, Doruk, Sturluson, Arni, Einarsson, Hafsteinn, Tragante, Vinicius, Helgason, Hannes, Lund, Sigrun H., Halldorsson, Bjarni V., Sigurpalsdottir, Brynja D., Olafsson, Isleifur, Arnar, David O., Thorgeirsson, Gudmundur, Knowlton, Kirk U., Nadauld, Lincoln D., Gretarsdottir, Solveig, Helgadottir, Anna, Ostrowski, Sisse R., Gudbjartssson, Daniel F., Jonsdottir, Ingileif, Bundgaard, Henning, Holm, Hilma, Sulem, Patrick, Stefansson, Kari
Published in JAMA Cardiology (2024)

Genetic variability in the absorption of dietary sterols affects the risk of coronary artery disease

by Helgadottir, Anna, Thorleifsson, Gudmar, Alexandersson, Kristjan F, Tragante, Vinicius, Þorsteinsdóttir, Margrét, Eiriksson, Finnur Freyr, Grétarsdóttir, Sólveig, Björnsson, Eyþór, Magnússon, Ólafur, Sveinbjornsson, Gardar, Jonsdottir, Ingileif, Steinthorsdottir, Valgerdur, Ferkingstad, Egil, Jensson, Brynjar Ö, Stefansson, Hreinn, Olafsson, Isleifur, Christensen, Alex H, Torp-Pedersen, Christian, Køber, Lars, Pedersen, Ole B, Erikstrup, Christian, Sørensen, Erik, Brunak, Søren, Banasik, Karina, Hansen, Thomas F, Nyegaard, Mette, Eyjólfsson, Guðmundur I., Sigurdardottir, Olof, Þórarinsson, Björn L, Matthíasson, Stefán E., Steingrimsdottir, Thora, Björnsson, Einar Stefán, Danielsen, Ragnar, Asselbergs, Folkert W., Arnar, David O, Ullum, Henrik, Bundgaard, Henning, sulem, patrick, Thorsteinsdottir, Unnur, Thorgeirsson, Gudmundur, Holm, Hilma, Gudbjartsson, Daniel, Stefansson, Kari
Published in European Heart Journal (2020)

Variants at the Interleukin 1 Gene Locus and Pericarditis

by Thorolfsdottir, Rosa B., Jonsdottir, Andrea B., Sveinbjornsson, Gardar, Aegisdottir, Hildur M., Oddsson, Asmundur, Stefansson, Olafur A., Halldorsson, Gisli H., Saevarsdottir, Saedis, Thorleifsson, Gudmar, Stefansdottir, Lilja, Pedersen, Ole B., Sørensen, Erik, Ghouse, Jonas, Raja, Anna Axelsson, Zheng, Chaoqun, Silajdzija, Elvira, Rand, Søren Albertsen, Erikstrup, Christian, Ullum, Henrik, Mikkelsen, Christina, Banasik, Karina, Brunak, Søren, Ivarsdottir, Erna V., Sigurdsson, Asgeir, Beyter, Doruk, Sturluson, Arni, Einarsson, Hafsteinn, Tragante, Vinicius, Helgason, Hannes, Lund, Sigrun H., Halldorsson, Bjarni V., Sigurpalsdottir, Brynja D., Olafsson, Isleifur, Arnar, David O., Thorgeirsson, Gudmundur, Knowlton, Kirk U., Nadauld, Lincoln D., Gretarsdottir, Solveig, Helgadottir, Anna, Ostrowski, Sisse R., Gudbjartssson, Daniel F., Jonsdottir, Ingileif, Bundgaard, Henning, Holm, Hilma, Sulem, Patrick, Stefansson, Kari, Bay, Jakob, Boldsen, Jens K., Brodersen, Thorsten, Burgdorf, Kristoffer, Chalmer, Mona A., Didriksen, Maria, Dinh, Khoa M., Dowsett, Joseph, Feenstra, Bjarke, Geller, Frank, Gudbjartsson, Daniel, Hansen, Thomas F., Hindhede, Lotte, Hjalgrim, Henrik, Jacobsen, Rikke L., Jemec, Gregor, Jensen, Bitten A., Kaspersen, Katrine, Kjerulff, Bertram D., Kogelman, Lisette, Larsen, Margit A. H., Louloudis, Ioannis, Lundgaard, Agnete, Mikkelsen, Susan, Nissen, Ioanna, Nyegaard, Mette, Pedersen, Ole Birger, Henriksen, Alexander P., Rohde, Palle D., Rostgaard, Klaus, Schwinn, Michael, Stefánsson, Hreinn, Thorsteinsdóttir, Unnur, Thørner, Lise W., Topholm Bruun, Mie, Werge, Thomas, Westergaard, David
Published in JAMA Cardiology (2024)

Genetic variability in the absorption of dietary sterols affects the risk of coronary artery disease.

by Helgadottir, Anna, Thorleifsson, Gudmar, Alexandersson, Kristjan F, Tragante, Vinicius, Thorsteinsdottir, Margret, Eiriksson, Finnur F, Gretarsdottir, Solveig, Björnsson, Eythór, Magnusson, Olafur, Sveinbjornsson, Gardar, Jonsdottir, Ingileif, Steinthorsdottir, Valgerdur, Ferkingstad, Egil, Jensson, Brynjar Ö, Stefansson, Hreinn, Olafsson, Isleifur, Christensen, Alex H, Torp-Pedersen, Christian, Køber, Lars, Pedersen, Ole B, Erikstrup, Christian, Sørensen, Erik, Brunak, Søren, Banasik, Karina, Hansen, Thomas F, Nyegaard, Mette, Eyjolfssson, Gudmundur I, Sigurdardottir, Olof, Thorarinsson, Bjorn L, Matthiasson, Stefan E, Steingrimsdottir, Thora, Bjornsson, Einar S, Danielsen, Ragnar, Asselbergs, Folkert W, Arnar, David O, Ullum, Henrik, Bundgaard, Henning, Sulem, Patrick, Thorsteinsdottir, Unnur, Thorgeirsson, Gudmundur, Holm, Hilma, Gudbjartsson, Daniel F, Stefansson, Kari
Published in European Heart Journal (2020)

Common and rare variants associated with kidney stones and biochemical traits.

by Oddsson, Asmundur, Sulem, Patrick, Helgason, Hannes, Edvardsson, Vidar O, Thorleifsson, Gudmar, Sveinbjörnsson, Gardar, Haraldsdottir, Eik, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Olafsson, Isleifur, Masson, Gisli, Holm, Hilma, Gudbjartsson, Daniel F, Thorsteinsdottir, Unnur, Indridason, Olafur S, Palsson, Runolfur, Stefansson, Kari
Published in Nature Communications (2015)

Identification of sequence variants influencing immunoglobulin levels.

by Jonsson, Stefan, Sveinbjornsson, Gardar, de Lapuente Portilla, Aitzkoa Lopez, Swaminathan, Bhairavi, Plomp, Rosina, Dekkers, Gillian, Ajore, Ram, Ali, Mina, Bentlage, Arthur E H, Elmér, Evelina, Eyjolfsson, Gudmundur I, Gudjonsson, Sigurjon A, Gullberg, Urban, Gylfason, Arnaldur, Halldorsson, Bjarni V, Hansson, Markus, Holm, Hilma, Johansson, Åsa, Johnsson, Ellinor, Jonasdottir, Aslaug, Ludviksson, Bjorn R, Oddsson, Asmundur, Olafsson, Isleifur, Olafsson, Sigurgeir, Sigurdardottir, Olof, Sigurdsson, Asgeir, Stefansdottir, Lilja, Masson, Gisli, Sulem, Patrick, Wuhrer, Manfred, Wihlborg, Anna-Karin, Thorleifsson, Gudmar, Gudbjartsson, Daniel F, Thorsteinsdottir, Unnur, Vidarsson, Gestur, Jonsdottir, Ingileif, Nilsson, Björn, Stefansson, Kari
Published in Nature Genetics (2017)

Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits.

by Styrkarsdottir, Unnur, Thorleifsson, Gudmar, Sulem, Patrick, Gudbjartsson, Daniel F, Sigurdsson, Asgeir, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Oddsson, Asmundur, Helgason, Agnar, Magnusson, Olafur T, Walters, G Bragi, Frigge, Michael L, Helgadottir, Hafdis T, Johannsdottir, Hrefna, Bergsteinsdottir, Kristin, Ogmundsdottir, Margret H, Center, Jacqueline R, Nguyen, Tuan V, Eisman, John A, Christiansen, Claus, Steingrimsson, Erikur, Jonasson, Jon G, Tryggvadottir, Laufey, Eyjolfsson, Gudmundur I, Theodors, Asgeir, Jonsson, Thorvaldur, Ingvarsson, Thorvaldur, Olafsson, Isleifur, Rafnar, Thorunn, Kong, Augustine, Sigurdsson, Gunnar, Masson, Gisli, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in Nature (2014)

Large-scale whole-genome sequencing of the Icelandic population.

by Gudbjartsson, Daniel F, Helgason, Hannes, Gudjonsson, Sigurjon A, Zink, Florian, Oddson, Asmundur, Gylfason, Arnaldur, Besenbacher, Soren, Magnusson, Gisli, Halldorsson, Bjarni V, Hjartarson, Eirikur, Sigurdsson, Gunnar Th, Stacey, Simon N, Frigge, Michael L, Holm, Hilma, Saemundsdottir, Jona, Helgadottir, Hafdis Th, Johannsdottir, Hrefna, Sigfusson, Gunnlaugur, Thorgeirsson, Gudmundur, Sverrisson, Jon Th, Gretarsdottir, Solveig, Walters, G Bragi, Rafnar, Thorunn, Thjodleifsson, Bjarni, Bjornsson, Einar S, Olafsson, Sigurdur, Thorarinsdottir, Hildur, Steingrimsdottir, Thora, Gudmundsdottir, Thora S, Theodors, Asgeir, Jonasson, Jon G, Sigurdsson, Asgeir, Bjornsdottir, Gyda, Jonsson, Jon J, Thorarensen, Olafur, Ludvigsson, Petur, Gudbjartsson, Hakon, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Olafsson, Isleifur, Arnar, David O, Magnusson, Olafur Th, Kong, Augustine, Masson, Gisli, Thorsteinsdottir, Unnur, Helgason, Agnar, Sulem, Patrick, Stefansson, Kari
Published in Nature Genetics (2015)

Identification of Common Genetic Variants Influencing Spontaneous Dizygotic Twinning and Female Fertility.

by Mbarek, Hamdi, Steinberg, Stacy, Nyholt, Dale R, Gordon, Scott D, Miller, Michael B, McRae, Allan F, Hottenga, Jouke Jan, Day, Felix R, Willemsen, Gonneke, de Geus, Eco J, Davies, Gareth E, Martin, Hilary C, Penninx, Brenda W, Jansen, Rick, McAloney, Kerrie, Vink, Jacqueline M, Kaprio, Jaakko, Plomin, Robert, Spector, Tim D, Magnusson, Patrik K, Reversade, Bruno, Harris, R Alan, Aagaard, Kjersti, Kristjansson, Ragnar P, Olafsson, Isleifur, Eyjolfsson, Gudmundur Ingi, Sigurdardottir, Olof, Iacono, William G, Lambalk, Cornelis B, Montgomery, Grant W, McGue, Matt, Ong, Ken K, Perry, John R B, Martin, Nicholas G, Stefánsson, Hreinn, Stefánsson, Kari, Boomsma, Dorret I
Published in The American Journal of Human Genetics (2016)