Wild pedigrees inform mutation rates and historic abundance in baleen whales
Phylogeny-based estimates suggesting a low germline mutation rate (μ) in baleen whales have influenced research ranging from assessments of whaling impacts to evolutionary cancer biology. We estimated μ directly from pedigrees in four baleen whale species for both the mitochondrial control region an...
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Online Access: | https://zenodo.org/record/8306163 https://doi.org/10.5061/dryad.9kd51c5pq |
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ftzenodo:oai:zenodo.org:8306163 2023-10-01T03:54:54+02:00 Wild pedigrees inform mutation rates and historic abundance in baleen whales Suárez-Menéndez, Marcos Bérubé, Martine Furni, Fabrício Rivera-Leon, Vania Heide-Jørgensen, Mads Peter Larsen, Finn Sears, Richard Ramp, Christian Eriksson, Britas Klemens Etienne, Rampal Robbins, Jooke Palsbøll, Per 2023-08-31 https://zenodo.org/record/8306163 https://doi.org/10.5061/dryad.9kd51c5pq unknown doi:10.1101/2022.10.06.510775 https://zenodo.org/communities/dryad https://zenodo.org/record/8306163 https://doi.org/10.5061/dryad.9kd51c5pq oai:zenodo.org:8306163 info:eu-repo/semantics/openAccess https://creativecommons.org/publicdomain/zero/1.0/legalcode pedigree baleen whales mutation rate info:eu-repo/semantics/other dataset 2023 ftzenodo https://doi.org/10.5061/dryad.9kd51c5pq10.1101/2022.10.06.510775 2023-09-05T22:58:56Z Phylogeny-based estimates suggesting a low germline mutation rate (μ) in baleen whales have influenced research ranging from assessments of whaling impacts to evolutionary cancer biology. We estimated μ directly from pedigrees in four baleen whale species for both the mitochondrial control region and nuclear genome. The results suggest values higher than those obtained through phylogeny-based estimates and similar to pedigree-based values for primates and toothed whales. Applying our estimate of μ reduces previous genetic–based estimates of pre-exploitation whale abundance by 86% and suggests that μ cannot explain low cancer rates in gigantic mammals. Our study shows that it is feasible to estimate μ directly from pedigrees in natural populations, with wide-ranging implications for ecological and evolutionary research. Funding provided by: H2020 Marie Skłodowska-Curie ActionsCrossref Funder Registry ID: http://dx.doi.org/10.13039/100010665Award Number: 813383Funding provided by: National Marine Fisheries ServiceCrossref Funder Registry ID: http://dx.doi.org/10.13039/100013408Award Number: Funding provided by: Rijksuniversiteit GroningenCrossref Funder Registry ID: http://dx.doi.org/10.13039/501100001721Award Number: Funding provided by: Aage V. Jensens FondeCrossref Funder Registry ID: http://dx.doi.org/10.13039/501100002721Award Number: Funding provided by: Consejo Nacional de Ciencia y TecnologíaCrossref Funder Registry ID: http://dx.doi.org/10.13039/501100003141Award Number: Funding provided by: WWF VerdensnaturfondenCrossref Funder Registry ID: http://dx.doi.org/10.13039/501100013939Award Number: Funding provided by: International Whaling Comission Scientific CommitteeAward Number: Funding provided by: Kommissionen for Videnskabelige Undersøgelser i GrønlandCrossref Funder Registry ID: http://dx.doi.org/10.13039/501100004797Award Number: Funding provided by: Greenland Home RuleAward Number: Dataset baleen whale baleen whales Greenland toothed whales Zenodo Greenland |
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Open Polar |
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Zenodo |
op_collection_id |
ftzenodo |
language |
unknown |
topic |
pedigree baleen whales mutation rate |
spellingShingle |
pedigree baleen whales mutation rate Suárez-Menéndez, Marcos Bérubé, Martine Furni, Fabrício Rivera-Leon, Vania Heide-Jørgensen, Mads Peter Larsen, Finn Sears, Richard Ramp, Christian Eriksson, Britas Klemens Etienne, Rampal Robbins, Jooke Palsbøll, Per Wild pedigrees inform mutation rates and historic abundance in baleen whales |
topic_facet |
pedigree baleen whales mutation rate |
description |
Phylogeny-based estimates suggesting a low germline mutation rate (μ) in baleen whales have influenced research ranging from assessments of whaling impacts to evolutionary cancer biology. We estimated μ directly from pedigrees in four baleen whale species for both the mitochondrial control region and nuclear genome. The results suggest values higher than those obtained through phylogeny-based estimates and similar to pedigree-based values for primates and toothed whales. Applying our estimate of μ reduces previous genetic–based estimates of pre-exploitation whale abundance by 86% and suggests that μ cannot explain low cancer rates in gigantic mammals. Our study shows that it is feasible to estimate μ directly from pedigrees in natural populations, with wide-ranging implications for ecological and evolutionary research. Funding provided by: H2020 Marie Skłodowska-Curie ActionsCrossref Funder Registry ID: http://dx.doi.org/10.13039/100010665Award Number: 813383Funding provided by: National Marine Fisheries ServiceCrossref Funder Registry ID: http://dx.doi.org/10.13039/100013408Award Number: Funding provided by: Rijksuniversiteit GroningenCrossref Funder Registry ID: http://dx.doi.org/10.13039/501100001721Award Number: Funding provided by: Aage V. Jensens FondeCrossref Funder Registry ID: http://dx.doi.org/10.13039/501100002721Award Number: Funding provided by: Consejo Nacional de Ciencia y TecnologíaCrossref Funder Registry ID: http://dx.doi.org/10.13039/501100003141Award Number: Funding provided by: WWF VerdensnaturfondenCrossref Funder Registry ID: http://dx.doi.org/10.13039/501100013939Award Number: Funding provided by: International Whaling Comission Scientific CommitteeAward Number: Funding provided by: Kommissionen for Videnskabelige Undersøgelser i GrønlandCrossref Funder Registry ID: http://dx.doi.org/10.13039/501100004797Award Number: Funding provided by: Greenland Home RuleAward Number: |
format |
Dataset |
author |
Suárez-Menéndez, Marcos Bérubé, Martine Furni, Fabrício Rivera-Leon, Vania Heide-Jørgensen, Mads Peter Larsen, Finn Sears, Richard Ramp, Christian Eriksson, Britas Klemens Etienne, Rampal Robbins, Jooke Palsbøll, Per |
author_facet |
Suárez-Menéndez, Marcos Bérubé, Martine Furni, Fabrício Rivera-Leon, Vania Heide-Jørgensen, Mads Peter Larsen, Finn Sears, Richard Ramp, Christian Eriksson, Britas Klemens Etienne, Rampal Robbins, Jooke Palsbøll, Per |
author_sort |
Suárez-Menéndez, Marcos |
title |
Wild pedigrees inform mutation rates and historic abundance in baleen whales |
title_short |
Wild pedigrees inform mutation rates and historic abundance in baleen whales |
title_full |
Wild pedigrees inform mutation rates and historic abundance in baleen whales |
title_fullStr |
Wild pedigrees inform mutation rates and historic abundance in baleen whales |
title_full_unstemmed |
Wild pedigrees inform mutation rates and historic abundance in baleen whales |
title_sort |
wild pedigrees inform mutation rates and historic abundance in baleen whales |
publishDate |
2023 |
url |
https://zenodo.org/record/8306163 https://doi.org/10.5061/dryad.9kd51c5pq |
geographic |
Greenland |
geographic_facet |
Greenland |
genre |
baleen whale baleen whales Greenland toothed whales |
genre_facet |
baleen whale baleen whales Greenland toothed whales |
op_relation |
doi:10.1101/2022.10.06.510775 https://zenodo.org/communities/dryad https://zenodo.org/record/8306163 https://doi.org/10.5061/dryad.9kd51c5pq oai:zenodo.org:8306163 |
op_rights |
info:eu-repo/semantics/openAccess https://creativecommons.org/publicdomain/zero/1.0/legalcode |
op_doi |
https://doi.org/10.5061/dryad.9kd51c5pq10.1101/2022.10.06.510775 |
_version_ |
1778522930862358528 |