Wild pedigrees inform mutation rates and historic abundance in baleen whales
Phylogeny-based estimates suggesting a low germline mutation rate (μ) in baleen whales have influenced research ranging from assessments of whaling impacts to evolutionary cancer biology. We estimated μ directly from pedigrees in four baleen whale species for both the mitochondrial control region an...
Main Authors: | , , , , , , , , , , , |
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Format: | Dataset |
Language: | unknown |
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2023
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Online Access: | https://zenodo.org/record/8306163 https://doi.org/10.5061/dryad.9kd51c5pq |
Summary: | Phylogeny-based estimates suggesting a low germline mutation rate (μ) in baleen whales have influenced research ranging from assessments of whaling impacts to evolutionary cancer biology. We estimated μ directly from pedigrees in four baleen whale species for both the mitochondrial control region and nuclear genome. The results suggest values higher than those obtained through phylogeny-based estimates and similar to pedigree-based values for primates and toothed whales. Applying our estimate of μ reduces previous genetic–based estimates of pre-exploitation whale abundance by 86% and suggests that μ cannot explain low cancer rates in gigantic mammals. Our study shows that it is feasible to estimate μ directly from pedigrees in natural populations, with wide-ranging implications for ecological and evolutionary research. Funding provided by: H2020 Marie Skłodowska-Curie ActionsCrossref Funder Registry ID: http://dx.doi.org/10.13039/100010665Award Number: 813383Funding provided by: National Marine Fisheries ServiceCrossref Funder Registry ID: http://dx.doi.org/10.13039/100013408Award Number: Funding provided by: Rijksuniversiteit GroningenCrossref Funder Registry ID: http://dx.doi.org/10.13039/501100001721Award Number: Funding provided by: Aage V. Jensens FondeCrossref Funder Registry ID: http://dx.doi.org/10.13039/501100002721Award Number: Funding provided by: Consejo Nacional de Ciencia y TecnologíaCrossref Funder Registry ID: http://dx.doi.org/10.13039/501100003141Award Number: Funding provided by: WWF VerdensnaturfondenCrossref Funder Registry ID: http://dx.doi.org/10.13039/501100013939Award Number: Funding provided by: International Whaling Comission Scientific CommitteeAward Number: Funding provided by: Kommissionen for Videnskabelige Undersøgelser i GrønlandCrossref Funder Registry ID: http://dx.doi.org/10.13039/501100004797Award Number: Funding provided by: Greenland Home RuleAward Number: |
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