Identification of a novel coronavirus from a beluga whale by using a panviral microarray

The emergence of viruses such as severe acute respiratory syndrome coronavirus and Nipah virus has underscored the role of animal reservoirs in human disease and the need for reservoir surveillance. Here, we used a panviral DNA microarray to investigate the death of a captive beluga whale in an aqua...

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Bibliographic Details
Published in:Journal of Virology
Main Authors: Mihindukulasuriya, Kathie A., Wu, Guang, St Leger, Judy, Nordhausen, Robert W., Wang, David
Other Authors: Plazi
Format: Article in Journal/Newspaper
Language:English
Published: 2008
Subjects:
covid
covid-19
Coronavirus
Beluga Whale
Sequence Homology
Gene Order
Sequence Analysis
DNA
Coronaviridae
Coronavirus Infections
pathogens
Liver
Viridae
Animals
Genome
Viral
Phylogeny
biotic interaction
virus-host
Male
corona viruses
biotic associations
CETAF-taskforce
biotic relations
pathogen-host
Oligonucleotide Array Sequence Analysis
Molecular Sequence Data
Beluga
Beluga whale
Beluga*
Online Access:https://zenodo.org/record/3948986
https://doi.org/10.1128/JVI.02722-07
Description
Summary:The emergence of viruses such as severe acute respiratory syndrome coronavirus and Nipah virus has underscored the role of animal reservoirs in human disease and the need for reservoir surveillance. Here, we used a panviral DNA microarray to investigate the death of a captive beluga whale in an aquatic park. A highly divergent coronavirus, tentatively named coronavirus SW1, was identified in liver tissue from the deceased whale. Subsequently, the entire genome of SW1 was sequenced, yielding a genome of 31,686 nucleotides. Phylogenetic analysis revealed SW1 to be a novel virus distantly related to but most similar to group III coronaviruses.

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