PAH metabolites in fish bile: From the Seine estuary to Iceland

Polycyclic aromatic hydrocarbons (PAH) are environmental contaminants that pose significant risk to health of fish. The International Workshop on Integrated Assessment of Contaminant Impacts on the North Sea (ICON) provided the framework to investigate biomarker responses as well as contaminant conc...

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Bibliographic Details
Published in:Marine Environmental Research
Main Authors: Kammann, U., Akcha, F., Budzinski, H., Burgeot, T., Gubbins, M. J., Lang, T., Le Menach, K., Vethaak, A. D., Hylland, K.
Format: Article in Journal/Newspaper
Language:English
Published: 2017
Subjects:
Online Access:https://research.vu.nl/en/publications/e59efd93-ece8-47e0-b641-7f7282e24021
https://doi.org/10.1016/j.marenvres.2016.02.014
https://hdl.handle.net/1871.1/e59efd93-ece8-47e0-b641-7f7282e24021
https://research.vu.nl/ws/files/278990322/PAH_metabolites_in_fish_bile_From_the_Seine_estuary_to_Iceland.pdf
http://www.scopus.com/inward/record.url?scp=84959898570&partnerID=8YFLogxK
http://www.scopus.com/inward/citedby.url?scp=84959898570&partnerID=8YFLogxK
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Summary:Polycyclic aromatic hydrocarbons (PAH) are environmental contaminants that pose significant risk to health of fish. The International Workshop on Integrated Assessment of Contaminant Impacts on the North Sea (ICON) provided the framework to investigate biomarker responses as well as contaminant concentrations side by side in marine ecosystems. Concentrations of the main PAH metabolites 1-hydroxypyrene, 1-hydroxyphenanthren and 3-hydroxybenzo(a)pyrene were determined in bile by HPLC with fluorescence detection. Fish species under investigation were dab (Limanda limanda), flounder (Platichthys flesus) and haddock (Melanogrammus aeglefinus). A contamination gradient was demonstrated from the low contaminated waters of Iceland and off-shore regions of the North Sea towards higher concentrations in coastal areas. Concentrations of PAH metabolites differed primarily according to sampling region and secondarily to species.