Natural Antimicrobials from Cloudberry ( Rubus chamaemorus ) Seeds by Sanding and Hydrothermal Extraction

We have developed an organic solvent-free process to enrich natural antimicrobials from the important Nordic Rubus berry species, especially from cloudberry. The process utilizes industrial berry byproducts as raw-material, and it is based on seed sanding technology and water-based extraction. The e...

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Bibliographic Details
Published in:ACS Food Science & Technology
Main Authors: Puupponen-pimiä, Riitta, Nohynek, Liisa, Suvanto, Jussi, Salminen, Juha-pekka, Seppänen-laakso, Tuulikki, Tähtiharju, Juha, Honkapää, Kaisu, Oksman-caldentey, Kirsi-marja
Format: Article in Journal/Newspaper
Language:English
Published: 2021
Subjects:
Rubus species
berries
byproducts
seeds
antimicrobial activity
MRSA
/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
name=SDG 3 - Good Health and Well-being
Rubus chamaemorus
Online Access:https://cris.vtt.fi/en/publications/b31143be-461d-419f-a234-70a7e8eb83cb
https://doi.org/10.1021/acsfoodscitech.0c00109
https://cris.vtt.fi/ws/files/52245018/acsfoodscitech.0c00109.pdf
http://www.scopus.com/inward/record.url?scp=85120069645&partnerID=8YFLogxK
Description
Summary:We have developed an organic solvent-free process to enrich natural antimicrobials from the important Nordic Rubus berry species, especially from cloudberry. The process utilizes industrial berry byproducts as raw-material, and it is based on seed sanding technology and water-based extraction. The extracts showed strong antimicrobial activity against Gram-positive Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA). A concentration of 5 mg/mL totally eliminated these bacteria in 24 h. Effects against Gram-negative bacteria were modest. Polyphenol analysis of the hydrothermal extracts showed that the antimicrobial activity is correlated to ellagitannins, mainly dimeric sanguiin H-6 and sanguiin H-10 isomers. Sanguiin H-10 is not commonly found in intact cloudberry seeds, but it is formed from the dimeric and trimeric ellagitannins, during the extraction. Surprisingly hydrothermal extracts had no or minor effects on beneficial bacteria, Lactobacillus rhamnosus. This interesting finding might offer an application potential in controlling skin microbial pathogens, for example, in wound healing.

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