NARWHAL, a primary analysis pipeline for NGS data

The NARWHAL software pipeline has been developed to automate the primary analysis of Illumina sequencing data. This pipeline combines a new and flexible de-multiplexing tool with open-source aligners and automated quality assessment. The entire pipeline can be run using only one simple sample-sheet...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Brouwer, Rutger, van den Hout, MCGN, Grosveld, Frank, van Ijcken, Wilfred
Format: Article in Journal/Newspaper
Language:unknown
Published: 2012
Subjects:
Online Access:https://pure.eur.nl/en/publications/9a6b70db-7a81-4a91-bfaf-cf9ca9d37d56
https://doi.org/10.1093/bioinformatics/btr613
http://hdl.handle.net/1765/34835
Description
Summary:The NARWHAL software pipeline has been developed to automate the primary analysis of Illumina sequencing data. This pipeline combines a new and flexible de-multiplexing tool with open-source aligners and automated quality assessment. The entire pipeline can be run using only one simple sample-sheet for diverse sequencing applications. NARWHAL creates a sample-oriented data structure and outperforms existing tools in speed.