Identification and Characterization of Two Novel Viruses in Ocular Infections in Reindeer
A thorough understanding of virus diversity in wildlife provides epidemiological baseline information about pathogens. In this study, eye swab samples were obtained from semi-domesticated reindeer (Rangifer tarandus tarandus) in Norway during an outbreak of infectious eye disease, possibly a very ea...
| Published in: | PLoS ONE |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Article in Journal/Newspaper |
| Language: | unknown |
| Published: |
2013
|
| Subjects: | |
| Online Access: | https://pure.eur.nl/en/publications/054a3568-90c2-4901-bef5-d3eef9b1ab4c https://doi.org/10.1371/journal.pone.0069711 https://pure.eur.nl/ws/files/47529869/journal.pone.0069711.pdf http://hdl.handle.net/1765/70524 |
| Summary: | A thorough understanding of virus diversity in wildlife provides epidemiological baseline information about pathogens. In this study, eye swab samples were obtained from semi-domesticated reindeer (Rangifer tarandus tarandus) in Norway during an outbreak of infectious eye disease, possibly a very early stage of infectious keratoconjunctivitis (IKC). Large scale molecular virus screening, based on host nucleic acid depletion, sequence-independent amplification and next-generation sequencing of partially purified viral nucleic acid, revealed the presence of a new papillomavirus in 2 out of 8 eye swab samples and a new betaherpesvirus in 3 out of 8 eye swab samples collected from animals with clinical signs and not in similar samples in 9 animals without clinical signs. Whether either virus was responsible for causing the clinical signs or in any respect was associated to the disease condition remains to be determined. |
|---|