Asthma, allergic rhinitis and atopic dermatitis in association with home environment-The RHINE study

• Published in: Science of The Total Environment
• Main Authors: Wang, Juan, Janson, Christer, Malinovschi, Andrei, Holm, Mathias, Franklin, Karl A., Modig, Lars, Johannessen, Ane, Schlünssen, Vivi, Gislason, Thorarinn, Jogi, Nils Oskar, Norbäck, Dan
• Format: Article in Journal/Newspaper
• Language: English
• Published: Uppsala universitet, Arbets- och miljömedicin 2022
• Subjects: Asthma; Allergic rhinitis; Atopic dermatitis; Home environment; Dampness; Indoor painting; Respiratory Medicine and Allergy; Lungmedicin och allergi; Norway; Iceland
• Online Access: http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-487105; https://doi.org/10.1016/j.scitotenv.2022.158609

We studied home environment exposures in relation to asthma, allergic rhinitis and atopic dermatitis among offspringof participants (parents) in the Respiratory Health in Northern Europe (RHINE) study (age <= 30 y). Totally 17,881 off-spring from Iceland, Norway, Sweden, Denmark and Estonia were included. Home environment exposures, includingdampness and mold, type of dwelling, construction year and indoor painting were registered through a questionnaireanswered by parents in thefirst follow up (RHINE II). The parents reported ten years later with in the frame of RHINEIII offspring's birth year and offspring's asthma, allergic rhinitis, atopic dermatitis. They also reported dampness andmold at home from RHINE II to RHINE III. The prevalence of offspring's asthma before 10 y, asthma after 10 y, allergicrhinitis at any age and atopic dermatitis at any age were 9.7 %, 4.3 %, 15.6 % and 17.3 %, respectively. Asthma before10 y was related to any indoor painting at RHINE II (OR = 1.14, 95%CI (1.02, 1.29)). Asthmaafter 10 y was associatedwith dampness/mold at home (OR = 1.33-1.62) and living in the newest buildings (constructed in 1986-2001