Antioxidant defenses in polar cod (Boreogadus saida) and responsiveness toward dietary crude oil exposure

Increasing anthropogenic activities in the Arctic pose the risk for accidental oil spills but our knowledge of ecotoxicological effects is still limited for Arctic organisms. This study aimed to provide insights in baseline levels of antioxidants in polar cod (Boreogadus saida) from different Arctic...

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Bibliographic Details
Published in:Marine Environmental Research
Main Authors: Vieweg, Ireen, Nahrgang, Jasmine, BENEDETTI, MAURA, LANZONI, ILARIA, REGOLI, Francesco
Other Authors: Benedetti, Maura, Lanzoni, Ilaria, Regoli, Francesco
Format: Article in Journal/Newspaper
Language:English
Published: 2017
Subjects:
Antioxidant
Arctic
Biotransformation
Boreogadus saida
Fish
Oil spill
Oxidative stre
Total oxyradical scavenging capacity
Oceanography
Aquatic Science
Pollution
polar cod
Online Access:http://hdl.handle.net/11566/250541
https://doi.org/10.1016/j.marenvres.2017.06.005
Description
Summary:Increasing anthropogenic activities in the Arctic pose the risk for accidental oil spills but our knowledge of ecotoxicological effects is still limited for Arctic organisms. This study aimed to provide insights in baseline levels of antioxidants in polar cod (Boreogadus saida) from different Arctic locations and investigate the susceptibility of this species to oxidative stress during a 32 day dietary crude oil exposure. Baseline levels of individual antioxidants and total oxyradical scavenging capacity (TOSC) varied among different Arctic fjords. Upon crude oil exposure, dose- and time-dependent polycyclic aromatic hydrocarbons (PAHs) biotransformation was evident through hepatic ethoxyresorufine-O-deethylase activity, glutathione S-transferase mRNA expression and biliary PAH metabolites. Changes in the activity of individual antioxidants and TOSC was, however, slight and transient upon exposure. In conclusion, biotransformation was clearly induced by the sub-lethal levels of crude oil in polar cod, while the antioxidant defense responded with high variability.

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