Effect of cortisol on Aquaporin expression in the esophagus of the European eel (Anguilla anguilla).
Long-term cortisol infusion into freshwater (FW)-adapted eels induced a significant increase in aquaporin-1 (AQP1) mRNA expression within the esophageal epithelium of migratory "silver" eels, but not in nonmigratory, immature "yellow" eels. Cortisol treatment had no significant e...
| Published in: | Annals of the New York Academy of Sciences |
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| Main Authors: | , , , , , |
| Format: | Article in Journal/Newspaper |
| Language: | English |
| Published: |
2005
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| Subjects: | |
| Online Access: | https://research-portal.st-andrews.ac.uk/en/researchoutput/effect-of-cortisol-on-aquaporin-expression-in-the-esophagus-of-the-european-eel-anguilla-anguilla(d483fefd-e545-4810-95d3-dcf00f8b78d4).html https://doi.org/10.1196/annals.1327.072 http://www.scopus.com/inward/record.url?scp=22144465802&partnerID=8YFLogxK |
| Summary: | Long-term cortisol infusion into freshwater (FW)-adapted eels induced a significant increase in aquaporin-1 (AQP1) mRNA expression within the esophageal epithelium of migratory "silver" eels, but not in nonmigratory, immature "yellow" eels. Cortisol treatment had no significant effect on the mRNA abundance of a second aquaporin-1 isoform, termed AQP1dup, which exhibited a highly variable expression profile among individual members of all fish groups. These results suggest that cortisol, at plasma concentrations similar to that found during FW/seawater (SW) acclimation, induces upregulation in AQP1 expression and thus increases esophageal water permeability during the migration of eels to the SW environment. |
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