Characterisation of a group of endogenous gammaretroviruses in the canine genome

Bioinformatics were used to identify and characterise 39 pol, 34 gag and five env gammaretroviruses within the canine (Canis lupus familiaris) reference genome. These endogenous retroviruses are monophyletic to the Canidae, predate the divergence of dogs and foxes and are fixed in 20 canine breeds e...

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Bibliographic Details
Published in:The Veterinary Journal
Main Authors: Tarlinton, Rachael E., Barfoot, Hannah K.R., Allen, Ceri E., Brown, Katherine, Gifford, Robert J., Emes, Richard D.
Format: Article in Journal/Newspaper
Language:unknown
Published: Elsevier 2013
Subjects:
Canine
Endogenous retroviruses
Gammaretroviruses
Canis lupus
Online Access:https://doi.org/10.1016/j.tvjl.2012.08.011
https://nottingham-repository.worktribe.com/file/1002534/1/Talintoncanine.pdf
https://nottingham-repository.worktribe.com/output/1002534
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Summary:Bioinformatics were used to identify and characterise 39 pol, 34 gag and five env gammaretroviruses within the canine (Canis lupus familiaris) reference genome. These endogenous retroviruses are monophyletic to the Canidae, predate the divergence of dogs and foxes and are fixed in 20 canine breeds examined. They are transcribed in normal canine tissue but are unlikely to be replication competent in dogs.

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