Preliminary success using hydrogen peroxide to treat Atlantic salmon Salmo salar L. affected with experimentally induced amoebic gill disease (AGD)
Currently the only effective and commercially used treatment for amoebic gill disease (AGD) in farmed Tasmanian Atlantic salmon is freshwater bathing. Hydrogen peroxide (H 2 O 2 ), commonly used throughout the aquaculture industry for a range of topical skin and gill infections, was trialled in vitr...
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Online Access: | https://doi.org/10.1111/j.1365-2761.2012.01422.x http://www.ncbi.nlm.nih.gov/pubmed/22882640 http://ecite.utas.edu.au/78592 |
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ftunivtasecite:oai:ecite.utas.edu.au:78592 2023-05-15T15:30:52+02:00 Preliminary success using hydrogen peroxide to treat Atlantic salmon Salmo salar L. affected with experimentally induced amoebic gill disease (AGD) Adams, MB Crosbie, PBB Nowak, BF 2012 https://doi.org/10.1111/j.1365-2761.2012.01422.x http://www.ncbi.nlm.nih.gov/pubmed/22882640 http://ecite.utas.edu.au/78592 en eng Blackwell Publishing Ltd http://dx.doi.org/10.1111/j.1365-2761.2012.01422.x Adams, MB and Crosbie, PBB and Nowak, BF, Preliminary success using hydrogen peroxide to treat Atlantic salmon Salmo salar L. affected with experimentally induced amoebic gill disease (AGD), Journal of Fish Diseases, 35, (11) pp. 839 -848. ISSN 0140-7775 (2012) [Refereed Article] http://www.ncbi.nlm.nih.gov/pubmed/22882640 http://ecite.utas.edu.au/78592 Agricultural and Veterinary Sciences Veterinary Sciences Veterinary Anaesthesiology and Intensive Care Refereed Article PeerReviewed 2012 ftunivtasecite https://doi.org/10.1111/j.1365-2761.2012.01422.x 2019-12-13T21:44:18Z Currently the only effective and commercially used treatment for amoebic gill disease (AGD) in farmed Tasmanian Atlantic salmon is freshwater bathing. Hydrogen peroxide (H 2 O 2 ), commonly used throughout the aquaculture industry for a range of topical skin and gill infections, was trialled in vitro and in vivo to ascertain its potential as an alternative treatment against AGD. Under in vitro conditions, trophozoites of Neoparamoeba perurans were exposed to three concentrations of H 2 O 2 in seawater (500, 1000 & 1500 mg.l -1 ) over four durations (10, 20, 30 & 60 min) each at two temperatures (12 & 18C). Trophozoite viability was assessed immediately post exposure and after 24 hours. A concentration/duration combinationof 1000 mg.l -1 for > 10 min demonstrated potent amoebicidal activity. Subsequently, Atlantic salmon mildly affected with experimentally induced AGD were treated with H 2 O 2 at 12 and 18C for 15 minutes at 1250 mg.l -1 and their re-infection rate compared to freshwater treated fish over 21 days. Significant differences in the percentage of filaments affected with hyperplastic lesions (in association with amoebae) and plasma osmolality were noted between treatment groups immediately post-bath. However, the results were largely equivocal in terms of disease resolution over a three week period following treatment. These data suggest that H 2 O 2 treatment in seawater successfully ameliorated a clinically light case of AGD under laboratory conditions. Article in Journal/Newspaper Atlantic salmon Salmo salar eCite UTAS (University of Tasmania) Journal of Fish Diseases n/a n/a |
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Open Polar |
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eCite UTAS (University of Tasmania) |
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ftunivtasecite |
language |
English |
topic |
Agricultural and Veterinary Sciences Veterinary Sciences Veterinary Anaesthesiology and Intensive Care |
spellingShingle |
Agricultural and Veterinary Sciences Veterinary Sciences Veterinary Anaesthesiology and Intensive Care Adams, MB Crosbie, PBB Nowak, BF Preliminary success using hydrogen peroxide to treat Atlantic salmon Salmo salar L. affected with experimentally induced amoebic gill disease (AGD) |
topic_facet |
Agricultural and Veterinary Sciences Veterinary Sciences Veterinary Anaesthesiology and Intensive Care |
description |
Currently the only effective and commercially used treatment for amoebic gill disease (AGD) in farmed Tasmanian Atlantic salmon is freshwater bathing. Hydrogen peroxide (H 2 O 2 ), commonly used throughout the aquaculture industry for a range of topical skin and gill infections, was trialled in vitro and in vivo to ascertain its potential as an alternative treatment against AGD. Under in vitro conditions, trophozoites of Neoparamoeba perurans were exposed to three concentrations of H 2 O 2 in seawater (500, 1000 & 1500 mg.l -1 ) over four durations (10, 20, 30 & 60 min) each at two temperatures (12 & 18C). Trophozoite viability was assessed immediately post exposure and after 24 hours. A concentration/duration combinationof 1000 mg.l -1 for > 10 min demonstrated potent amoebicidal activity. Subsequently, Atlantic salmon mildly affected with experimentally induced AGD were treated with H 2 O 2 at 12 and 18C for 15 minutes at 1250 mg.l -1 and their re-infection rate compared to freshwater treated fish over 21 days. Significant differences in the percentage of filaments affected with hyperplastic lesions (in association with amoebae) and plasma osmolality were noted between treatment groups immediately post-bath. However, the results were largely equivocal in terms of disease resolution over a three week period following treatment. These data suggest that H 2 O 2 treatment in seawater successfully ameliorated a clinically light case of AGD under laboratory conditions. |
format |
Article in Journal/Newspaper |
author |
Adams, MB Crosbie, PBB Nowak, BF |
author_facet |
Adams, MB Crosbie, PBB Nowak, BF |
author_sort |
Adams, MB |
title |
Preliminary success using hydrogen peroxide to treat Atlantic salmon Salmo salar L. affected with experimentally induced amoebic gill disease (AGD) |
title_short |
Preliminary success using hydrogen peroxide to treat Atlantic salmon Salmo salar L. affected with experimentally induced amoebic gill disease (AGD) |
title_full |
Preliminary success using hydrogen peroxide to treat Atlantic salmon Salmo salar L. affected with experimentally induced amoebic gill disease (AGD) |
title_fullStr |
Preliminary success using hydrogen peroxide to treat Atlantic salmon Salmo salar L. affected with experimentally induced amoebic gill disease (AGD) |
title_full_unstemmed |
Preliminary success using hydrogen peroxide to treat Atlantic salmon Salmo salar L. affected with experimentally induced amoebic gill disease (AGD) |
title_sort |
preliminary success using hydrogen peroxide to treat atlantic salmon salmo salar l. affected with experimentally induced amoebic gill disease (agd) |
publisher |
Blackwell Publishing Ltd |
publishDate |
2012 |
url |
https://doi.org/10.1111/j.1365-2761.2012.01422.x http://www.ncbi.nlm.nih.gov/pubmed/22882640 http://ecite.utas.edu.au/78592 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_relation |
http://dx.doi.org/10.1111/j.1365-2761.2012.01422.x Adams, MB and Crosbie, PBB and Nowak, BF, Preliminary success using hydrogen peroxide to treat Atlantic salmon Salmo salar L. affected with experimentally induced amoebic gill disease (AGD), Journal of Fish Diseases, 35, (11) pp. 839 -848. ISSN 0140-7775 (2012) [Refereed Article] http://www.ncbi.nlm.nih.gov/pubmed/22882640 http://ecite.utas.edu.au/78592 |
op_doi |
https://doi.org/10.1111/j.1365-2761.2012.01422.x |
container_title |
Journal of Fish Diseases |
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_version_ |
1766361333455912960 |