Cell-surface carbohydrate antigen(s) of wild-type Neoparamoeba spp are immunodominant in sea-cage cultured Atlantic salmon ( Salmo salar L ) affected by amebic gill disease (AGD)

A proportion of Atlantic salmon experimentally affected by amoebic gill disease (AGD) develop a serumantibody response to wild-type Neoparamoeba spp. These antibodies bind cell-surface epitope(s) and inmost cases the epitope(s) are sensitive to sodium periodate oxidation. In this study, blood was ob...

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Bibliographic Details
Published in:Aquaculture
Main Authors: Vincent, BN, Adams, MB, Nowak, BF, Morrison, RN
Format: Article in Journal/Newspaper
Language:English
Published: Elsevier Science Bv 2009
Subjects:
Agricultural and Veterinary Sciences
Fisheries Sciences
Fish Pests and Diseases
Atlantic salmon
Salmo salar
Online Access:https://doi.org/10.1016/j.aquaculture.2008.11.036
http://ecite.utas.edu.au/60139
Description
Summary:A proportion of Atlantic salmon experimentally affected by amoebic gill disease (AGD) develop a serumantibody response to wild-type Neoparamoeba spp. These antibodies bind cell-surface epitope(s) and inmost cases the epitope(s) are sensitive to sodium periodate oxidation. In this study, blood was obtained fromtriploid and diploid sea-farmed Atlantic salmon after 8, 10 and 13 months of sea-cage culture. An additionalgroup of Atlantic salmon broodstock was sampled at 15 months after transfer to sea. Anti-Neoparamoeba spp.(anti-NP) antibodies that bound cell-surface carbohydrate antigens of wild-type Neoparamoeba spp. weredetected in several of these samples. In all cases, the presence of plasma anti-NP antibodies does not appearto be associated with the level of AGD-like gross gill pathology. These results provide further evidence for thedevelopment of an antibody response in AGD-affected Atlantic salmon and that carbohydrate epitopes ofwild-type Neoparamoeba spp. are immunodominant.

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