The effect of levamisole as an adjuvant on the humoral immune response of Atlantic salmon ( Salmo salar L. )

Pre and post-smolt Atlantic salmon (Salmo salar L.) were administered a levamisole adjuvanted Vibrio anguillarum vaccine by bath or intraperitoneal (IP) injection. A significant serum anti-V. anguillarum antibody response was elicited in groups of fish administered an IP injection of bacterium only....

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Bibliographic Details
Main Authors: Morrison, RN, Nowak, BF, Carson, J
Format: Article in Journal/Newspaper
Language:English
Published: European Association of Fish Pathologists 2000
Subjects:
Agricultural and Veterinary Sciences
Fisheries Sciences
Fish Pests and Diseases
Atlantic salmon
Salmo salar
Online Access:http://ecite.utas.edu.au/18447
id ftunivtasecite:oai:ecite.utas.edu.au:18447
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spelling ftunivtasecite:oai:ecite.utas.edu.au:18447 2023-05-15T15:30:33+02:00 The effect of levamisole as an adjuvant on the humoral immune response of Atlantic salmon ( Salmo salar L. ) Morrison, RN Nowak, BF Carson, J 2000 http://ecite.utas.edu.au/18447 en eng European Association of Fish Pathologists Morrison, RN and Nowak, BF and Carson, J, The effect of levamisole as an adjuvant on the humoral immune response of Atlantic salmon ( Salmo salar L. ), Bulletin of European Association of Fish Pathologists, 20, (3) pp. 101-105. ISSN 0108-0288 (2000) [Refereed Article] http://ecite.utas.edu.au/18447 Agricultural and Veterinary Sciences Fisheries Sciences Fish Pests and Diseases Refereed Article PeerReviewed 2000 ftunivtasecite 2019-12-13T21:01:25Z Pre and post-smolt Atlantic salmon (Salmo salar L.) were administered a levamisole adjuvanted Vibrio anguillarum vaccine by bath or intraperitoneal (IP) injection. A significant serum anti-V. anguillarum antibody response was elicited in groups of fish administered an IP injection of bacterium only. Fish (pre and post-smolt) treated with the levamisole adjuvanted vaccine (IP and bath) showed a suppressed response relative to the respective positive (vaccinated) control groups. No detectable antibody response was elicited in fish not treated or treated with a placebo. Results from this trial suggest that levamisole as an adjuvant has a narrow range of efficacy. Article in Journal/Newspaper Atlantic salmon Salmo salar eCite UTAS (University of Tasmania)
institution Open Polar
collection eCite UTAS (University of Tasmania)
op_collection_id ftunivtasecite
language English
topic Agricultural and Veterinary Sciences
Fisheries Sciences
Fish Pests and Diseases
spellingShingle Agricultural and Veterinary Sciences
Fisheries Sciences
Fish Pests and Diseases
Morrison, RN
Nowak, BF
Carson, J
The effect of levamisole as an adjuvant on the humoral immune response of Atlantic salmon ( Salmo salar L. )
topic_facet Agricultural and Veterinary Sciences
Fisheries Sciences
Fish Pests and Diseases
description Pre and post-smolt Atlantic salmon (Salmo salar L.) were administered a levamisole adjuvanted Vibrio anguillarum vaccine by bath or intraperitoneal (IP) injection. A significant serum anti-V. anguillarum antibody response was elicited in groups of fish administered an IP injection of bacterium only. Fish (pre and post-smolt) treated with the levamisole adjuvanted vaccine (IP and bath) showed a suppressed response relative to the respective positive (vaccinated) control groups. No detectable antibody response was elicited in fish not treated or treated with a placebo. Results from this trial suggest that levamisole as an adjuvant has a narrow range of efficacy.
format Article in Journal/Newspaper
author Morrison, RN
Nowak, BF
Carson, J
author_facet Morrison, RN
Nowak, BF
Carson, J
author_sort Morrison, RN
title The effect of levamisole as an adjuvant on the humoral immune response of Atlantic salmon ( Salmo salar L. )
title_short The effect of levamisole as an adjuvant on the humoral immune response of Atlantic salmon ( Salmo salar L. )
title_full The effect of levamisole as an adjuvant on the humoral immune response of Atlantic salmon ( Salmo salar L. )
title_fullStr The effect of levamisole as an adjuvant on the humoral immune response of Atlantic salmon ( Salmo salar L. )
title_full_unstemmed The effect of levamisole as an adjuvant on the humoral immune response of Atlantic salmon ( Salmo salar L. )
title_sort effect of levamisole as an adjuvant on the humoral immune response of atlantic salmon ( salmo salar l. )
publisher European Association of Fish Pathologists
publishDate 2000
url http://ecite.utas.edu.au/18447
genre Atlantic salmon
Salmo salar
genre_facet Atlantic salmon
Salmo salar
op_relation Morrison, RN and Nowak, BF and Carson, J, The effect of levamisole as an adjuvant on the humoral immune response of Atlantic salmon ( Salmo salar L. ), Bulletin of European Association of Fish Pathologists, 20, (3) pp. 101-105. ISSN 0108-0288 (2000) [Refereed Article]
http://ecite.utas.edu.au/18447
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