The effect of levamisole as an adjuvant on the humoral immune response of Atlantic salmon ( Salmo salar L. )
Pre and post-smolt Atlantic salmon (Salmo salar L.) were administered a levamisole adjuvanted Vibrio anguillarum vaccine by bath or intraperitoneal (IP) injection. A significant serum anti-V. anguillarum antibody response was elicited in groups of fish administered an IP injection of bacterium only....
Main Authors: | , , |
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Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
European Association of Fish Pathologists
2000
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Subjects: | |
Online Access: | http://ecite.utas.edu.au/18447 |
Summary: | Pre and post-smolt Atlantic salmon (Salmo salar L.) were administered a levamisole adjuvanted Vibrio anguillarum vaccine by bath or intraperitoneal (IP) injection. A significant serum anti-V. anguillarum antibody response was elicited in groups of fish administered an IP injection of bacterium only. Fish (pre and post-smolt) treated with the levamisole adjuvanted vaccine (IP and bath) showed a suppressed response relative to the respective positive (vaccinated) control groups. No detectable antibody response was elicited in fish not treated or treated with a placebo. Results from this trial suggest that levamisole as an adjuvant has a narrow range of efficacy. |
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