A Piece of the Puzzle-Possible Mechanisms for Why Low Dietary EPA and DHA Cause Hepatic Lipid Accumulation in Atlantic Salmon (Salmo salar)

• Published in: Metabolites
• Main Authors: Hundal, Bjorg Kristine, Lutfi, Esmail, Sigholt, Trygve, Rosenlund, Grethe, Liland, Nina Sylvia, Glencross, Brett, Sissener, Nini Hedberg
• Other Authors: Norwegian Research Council, Norwegian Institute of Marine Research, NOFIMA AS, BioMar AS, Skretting Aquaculture Research Centre, Institute of Aquaculture, orcid:0000-0003-1167-8530
• Format: Article in Journal/Newspaper
• Language: English
• Published: MDPI 2022
• Subjects: lipid metabolism; EPA; DHA; robustness; Atlantic salmon; metabolomics; Slaughter; Salmo salar
• Online Access: http://hdl.handle.net/1893/34048; https://doi.org/10.3390/metabo12020159; http://dspace.stir.ac.uk/bitstream/1893/34048/1/metabolites-12-00159-v2.pdf

The present study aimed at elucidating the effects of graded levels of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on the hepatic metabolic health of Atlantic salmon reared in sea cages. Diets containing 10, 13, 16 and 35 g/kg EPA + DHA (designated diets 1.0, 1.3, 1.6 and 3.5, respect...