Enhanced bioavailability of eicosapentaenoic acid from fish oil after encapsulation within plant spore exines as microcapsules

Benefits of eicosapentaenoic acid (EPA) can be enhanced by raising their bioavailability through microencapsulation.Pollen can be emptied to form hollow shells, known as exines, and then used to encapsulate material,such as oils in a dry powder form.6 healthy volunteers ingested 4.6 g of fish oil co...

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Bibliographic Details
Published in:Lipids
Main Authors: Wakil, Ammar, Mackenzie, Grahame, Diego-Taboada, Alberto, Bell, J Gordon, Atkin, Stephen L
Other Authors: Hull Royal Infirmary, University of Hull, Institute of Aquaculture
Format: Article in Journal/Newspaper
Language:English
Published: Springer 2010
Subjects:
Exines
microencapsulation
eicosapentaenoic acid
bioavailability
Atlantic salmon Numbers of species
Atlantic salmon Conservation
Biodegradation
Atlantic salmon
Online Access:http://hdl.handle.net/1893/2528
https://doi.org/10.1007/s11745-010-3427-y
http://dspace.stir.ac.uk/bitstream/1893/2528/1/Hull%20final%20version_EE%20and%20exines.pdf
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Summary:Benefits of eicosapentaenoic acid (EPA) can be enhanced by raising their bioavailability through microencapsulation.Pollen can be emptied to form hollow shells, known as exines, and then used to encapsulate material,such as oils in a dry powder form.6 healthy volunteers ingested 4.6 g of fish oil containing 20% EPA in the form of ethyl-ester first alone and then as 1:1 microencapsulated powder of exines and fish oil.Serum bioavailability of EPA was measured by area under curve (AUC0-24).The mean AUC0-24 of EPA from ethyl-ester with exine(M=19.7,SD=4.3)was significantly higher than ethyl-ester without exines(M=2,SD=1.4,p

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