Effect of the arachidonic acid/vitamin E interaction on the immune response of juvenile Atlantic salmon (Salmo salar) challenged against Piscirickettsia salmonis

Atlantic salmon (Salmo salar) were fed 6 experimental dietscontaining three levels of arachidonic acid (ARA) (0.18 g kg−1, 0.28 g kg−1and 0.63 g kg−1for low, medium and high levels, respectively) and two levels of vitamin E (150 and 730mg kg−1for low and high levels, respectively). At the end of the...

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Bibliographic Details
Published in:Aquaculture Nutrition
Main Authors: Dantagnan, Patricio, Gonzalez, Katerina, Hevia, Martin, Betancor, Monica, Hernández, Adrián, Borquez, Aliro, Montero, Daniel
Other Authors: Temuco Catholic University, The Chile Foundation - Quillaipe Aquaculture Center, Institute of Aquaculture, Universidad de Las Palmas de Gran Canaria, orcid:0000-0003-1626-7458
Format: Article in Journal/Newspaper
Language:English
Published: Wiley-Blackwell 2017
Subjects:
arachidonic acid
Atlantic salmon
disease resistance
fish nutrition
health
vitamin E
Salmo salar
Online Access:http://hdl.handle.net/1893/23425
https://doi.org/10.1111/anu.12438
http://dspace.stir.ac.uk/bitstream/1893/23425/1/Dantagnan%20at%20al%202016.pdf
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Summary:Atlantic salmon (Salmo salar) were fed 6 experimental dietscontaining three levels of arachidonic acid (ARA) (0.18 g kg−1, 0.28 g kg−1and 0.63 g kg−1for low, medium and high levels, respectively) and two levels of vitamin E (150 and 730mg kg−1for low and high levels, respectively). At the end of the experimental period, fatty acids in the liver and immunity markers (lysozyme activity, respiratory burst and phagocytic activity) were determined and fish subjected to a challenge test against the salmonid rickettsial syndrome (SRS) pathogen. ARA, vitamin E or their interaction did not exert an effect on fish performance, whereas ARA alone clearly increased the deposition of ARA. Dietary vitamin E only enhanced liver vitamin E deposition, while the interaction of ARA and vitamin E influenced lysozyme activity and EPA/ARA ratio pointing out the effect of both nutrients on the fish immune system and metabolism. Only the medium concentration contributed to reducing mortality when the fish were exposed to the SRS pathogen. In conclusion, different levels of supplementation with ARA and vitamin E in the diet had no effect on productivity, but did have effects on immune markers and cumulative mortality when fish were exposed to the SRS pathogen.

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