Mixed-function oxidase activity and conjugating enzymes in two species of Antarctic fish

Enzyme activities of phase I and phase II of the hepatic detoxication system were investigated in two species of fish from the Ross Sea in Antarctica. The fish had extremely low phase I enzyme (BPMO and aldrin epoxidase). The reductase regenerating enzyme activities were comparable to those found in...

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Bibliographic Details
Published in:Marine Environmental Research
Main Authors: FOCARDI, S., FOSSI, M. C., LEONZIO, C., DI SIMPLICIO, P.
Other Authors: Focardi, S., Fossi, M. C., Leonzio, C.
Format: Article in Journal/Newspaper
Language:English
Published: 1989
Subjects:
antarctic fish
MFO activity
Antarctic
Ross Sea
Antarc*
Antarctica
Online Access:http://hdl.handle.net/11365/41469
https://doi.org/10.1016/0141-1136(89)90179-7
Description
Summary:Enzyme activities of phase I and phase II of the hepatic detoxication system were investigated in two species of fish from the Ross Sea in Antarctica. The fish had extremely low phase I enzyme (BPMO and aldrin epoxidase). The reductase regenerating enzyme activities were comparable to those found in fish of temperate seas. Transferases of cytosol showed highest activity in the conjugation of l-chloro-2.4-dinitrobenzene (CDNB) and little or no conjugation of other substrates. The GSSG reductase and the glutathione transferase with peroxidase activity (CuOOH substrate) were low; the Sedependent glutathione peroxidase activity was not detectable. Interspecific differences were found for most of the enzymes tested.

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