A multi-trial diagnostic tool in fin whale (Balaenoptera physalus) skin biopsies of the Pelagos Sanctuary (Mediterranean Sea) and the Gulf of California (Mexico)
The main objective of this study was to apply a set of sensitive non-lethal biomarkers in skin biopsies of fin whales (Balaenoptera physalus) to evaluate the toxicological status of this mysticete in the Pelagos Sanctuary (Mediterranean Sea) and in the Gulf of California (Sea of Cortez-Mexico). We d...
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Online Access: | http://hdl.handle.net/11365/40162 https://doi.org/10.1016/j.marenvres.2009.10.006 |
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ftunivsiena:oai:usiena-air.unisi.it:11365/40162 2024-02-11T10:02:20+01:00 A multi-trial diagnostic tool in fin whale (Balaenoptera physalus) skin biopsies of the Pelagos Sanctuary (Mediterranean Sea) and the Gulf of California (Mexico) FOSSI, M. C. URBAN, J. CASINI, S. MALTESE, S. SPINSANTI, G. PANTI, C. PORCELLONI, S. PANIGADA, S. LAURIANO, G. NIÑO-TORRES, C. ROJAS-BRACHO, L. JIMENEZ, B. MUÑOZ-ARNANZ, L. MARSILI, L. Fossi, M. C. Urban, J. Casini, S. Maltese, S. Spinsanti, G. Panti, C. Porcelloni, S. Panigada, S. Lauriano, G. NIÑO-TORRES, C. ROJAS-BRACHO, L. Jimenez, B. MUÑOZ-ARNANZ, L. Marsili, L. 2010 STAMPA http://hdl.handle.net/11365/40162 https://doi.org/10.1016/j.marenvres.2009.10.006 eng eng info:eu-repo/semantics/altIdentifier/pmid/19913904 info:eu-repo/semantics/altIdentifier/wos/WOS:000284442900007 volume:69 issue:1 firstpage:S17 lastpage:S20 numberofpages:4 journal:MARINE ENVIRONMENTAL RESEARCH http://hdl.handle.net/11365/40162 doi:10.1016/j.marenvres.2009.10.006 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-77957750127 info:eu-repo/semantics/closedAccess Balaenoptera physalu Mediterranean Sea skin biopsy Gulf of California OC PAH PBDE CYP1A1 CYP2B HSP70 ER AHR E2F-1 info:eu-repo/semantics/article 2010 ftunivsiena https://doi.org/10.1016/j.marenvres.2009.10.006 2024-01-23T23:17:30Z The main objective of this study was to apply a set of sensitive non-lethal biomarkers in skin biopsies of fin whales (Balaenoptera physalus) to evaluate the toxicological status of this mysticete in the Pelagos Sanctuary (Mediterranean Sea) and in the Gulf of California (Sea of Cortez-Mexico). We developed a ‘‘multi-trial diagnostic tool” (based on field and in vitro studies), combining molecular biomarkers (western blot of CYP1A1, CYP2B) and gene expression (qRT-PCR of HSP70, ERa, AHR, E2F-1) with the analysis of OCs, PAHs and PBDEs. The study revealed a higher level of toxicological stress in the Mediterranean fin whales. Article in Journal/Newspaper Balaenoptera physalus Fin whale Università degli Studi di Siena: USiena air Marine Environmental Research 69 S17 S20 |
institution |
Open Polar |
collection |
Università degli Studi di Siena: USiena air |
op_collection_id |
ftunivsiena |
language |
English |
topic |
Balaenoptera physalu Mediterranean Sea skin biopsy Gulf of California OC PAH PBDE CYP1A1 CYP2B HSP70 ER AHR E2F-1 |
spellingShingle |
Balaenoptera physalu Mediterranean Sea skin biopsy Gulf of California OC PAH PBDE CYP1A1 CYP2B HSP70 ER AHR E2F-1 FOSSI, M. C. URBAN, J. CASINI, S. MALTESE, S. SPINSANTI, G. PANTI, C. PORCELLONI, S. PANIGADA, S. LAURIANO, G. NIÑO-TORRES, C. ROJAS-BRACHO, L. JIMENEZ, B. MUÑOZ-ARNANZ, L. MARSILI, L. A multi-trial diagnostic tool in fin whale (Balaenoptera physalus) skin biopsies of the Pelagos Sanctuary (Mediterranean Sea) and the Gulf of California (Mexico) |
topic_facet |
Balaenoptera physalu Mediterranean Sea skin biopsy Gulf of California OC PAH PBDE CYP1A1 CYP2B HSP70 ER AHR E2F-1 |
description |
The main objective of this study was to apply a set of sensitive non-lethal biomarkers in skin biopsies of fin whales (Balaenoptera physalus) to evaluate the toxicological status of this mysticete in the Pelagos Sanctuary (Mediterranean Sea) and in the Gulf of California (Sea of Cortez-Mexico). We developed a ‘‘multi-trial diagnostic tool” (based on field and in vitro studies), combining molecular biomarkers (western blot of CYP1A1, CYP2B) and gene expression (qRT-PCR of HSP70, ERa, AHR, E2F-1) with the analysis of OCs, PAHs and PBDEs. The study revealed a higher level of toxicological stress in the Mediterranean fin whales. |
author2 |
Fossi, M. C. Urban, J. Casini, S. Maltese, S. Spinsanti, G. Panti, C. Porcelloni, S. Panigada, S. Lauriano, G. NIÑO-TORRES, C. ROJAS-BRACHO, L. Jimenez, B. MUÑOZ-ARNANZ, L. Marsili, L. |
format |
Article in Journal/Newspaper |
author |
FOSSI, M. C. URBAN, J. CASINI, S. MALTESE, S. SPINSANTI, G. PANTI, C. PORCELLONI, S. PANIGADA, S. LAURIANO, G. NIÑO-TORRES, C. ROJAS-BRACHO, L. JIMENEZ, B. MUÑOZ-ARNANZ, L. MARSILI, L. |
author_facet |
FOSSI, M. C. URBAN, J. CASINI, S. MALTESE, S. SPINSANTI, G. PANTI, C. PORCELLONI, S. PANIGADA, S. LAURIANO, G. NIÑO-TORRES, C. ROJAS-BRACHO, L. JIMENEZ, B. MUÑOZ-ARNANZ, L. MARSILI, L. |
author_sort |
FOSSI, M. C. |
title |
A multi-trial diagnostic tool in fin whale (Balaenoptera physalus) skin biopsies of the Pelagos Sanctuary (Mediterranean Sea) and the Gulf of California (Mexico) |
title_short |
A multi-trial diagnostic tool in fin whale (Balaenoptera physalus) skin biopsies of the Pelagos Sanctuary (Mediterranean Sea) and the Gulf of California (Mexico) |
title_full |
A multi-trial diagnostic tool in fin whale (Balaenoptera physalus) skin biopsies of the Pelagos Sanctuary (Mediterranean Sea) and the Gulf of California (Mexico) |
title_fullStr |
A multi-trial diagnostic tool in fin whale (Balaenoptera physalus) skin biopsies of the Pelagos Sanctuary (Mediterranean Sea) and the Gulf of California (Mexico) |
title_full_unstemmed |
A multi-trial diagnostic tool in fin whale (Balaenoptera physalus) skin biopsies of the Pelagos Sanctuary (Mediterranean Sea) and the Gulf of California (Mexico) |
title_sort |
multi-trial diagnostic tool in fin whale (balaenoptera physalus) skin biopsies of the pelagos sanctuary (mediterranean sea) and the gulf of california (mexico) |
publishDate |
2010 |
url |
http://hdl.handle.net/11365/40162 https://doi.org/10.1016/j.marenvres.2009.10.006 |
genre |
Balaenoptera physalus Fin whale |
genre_facet |
Balaenoptera physalus Fin whale |
op_relation |
info:eu-repo/semantics/altIdentifier/pmid/19913904 info:eu-repo/semantics/altIdentifier/wos/WOS:000284442900007 volume:69 issue:1 firstpage:S17 lastpage:S20 numberofpages:4 journal:MARINE ENVIRONMENTAL RESEARCH http://hdl.handle.net/11365/40162 doi:10.1016/j.marenvres.2009.10.006 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-77957750127 |
op_rights |
info:eu-repo/semantics/closedAccess |
op_doi |
https://doi.org/10.1016/j.marenvres.2009.10.006 |
container_title |
Marine Environmental Research |
container_volume |
69 |
container_start_page |
S17 |
op_container_end_page |
S20 |
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1790598262490660864 |