A multi-trial diagnostic tool in fin whale (Balaenoptera physalus) skin biopsies of the Pelagos Sanctuary (Mediterranean Sea) and the Gulf of California (Mexico)

The main objective of this study was to apply a set of sensitive non-lethal biomarkers in skin biopsies of fin whales (Balaenoptera physalus) to evaluate the toxicological status of this mysticete in the Pelagos Sanctuary (Mediterranean Sea) and in the Gulf of California (Sea of Cortez-Mexico). We d...

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Bibliographic Details
Published in:Marine Environmental Research
Main Authors: FOSSI, M. C., URBAN, J., CASINI, S., MALTESE, S., SPINSANTI, G., PANTI, C., PORCELLONI, S., PANIGADA, S., LAURIANO, G., NIÑO-TORRES, C., ROJAS-BRACHO, L., JIMENEZ, B., MUÑOZ-ARNANZ, L., MARSILI, L.
Other Authors: Fossi, M. C., Urban, J., Casini, S., Maltese, S., Spinsanti, G., Panti, C., Porcelloni, S., Panigada, S., Lauriano, G., Jimenez, B., Marsili, L.
Format: Article in Journal/Newspaper
Language:English
Published: 2010
Subjects:
Balaenoptera physalu
Mediterranean Sea
skin biopsy
Gulf of California
OC
PAH
PBDE
CYP1A1
CYP2B
HSP70
ER
AHR
E2F-1
Balaenoptera physalus
Fin whale
Online Access:http://hdl.handle.net/11365/40162
https://doi.org/10.1016/j.marenvres.2009.10.006
Description
Summary:The main objective of this study was to apply a set of sensitive non-lethal biomarkers in skin biopsies of fin whales (Balaenoptera physalus) to evaluate the toxicological status of this mysticete in the Pelagos Sanctuary (Mediterranean Sea) and in the Gulf of California (Sea of Cortez-Mexico). We developed a ‘‘multi-trial diagnostic tool” (based on field and in vitro studies), combining molecular biomarkers (western blot of CYP1A1, CYP2B) and gene expression (qRT-PCR of HSP70, ERa, AHR, E2F-1) with the analysis of OCs, PAHs and PBDEs. The study revealed a higher level of toxicological stress in the Mediterranean fin whales.

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