Atlantic salmon (Salmo salar L.) parr fed genetically modified soybeans and maize: Histological, digestive, metabolic, and immunological investigations

Physiological and health related responses to dietary inclusion of genetically modified (GM) full-fat soybean meal (Roundup Ready; GM-soy) and maize (MON810 Bt-maize; GM-maize), as well as non-parental, untransformed lines (nGM-soy and nGM-maize D2), were evaluated in farmed Atlantic salmon (Salmo s...

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Bibliographic Details
Published in:Research in Veterinary Science
Main Authors: A. M. BAKKE MCKELLEP, M. SANDEN, G. I. HEMRE, A. KROGDAHL, DANIELI, Antonio, ACIERNO, Raffaele, MAFFIA, Michele
Other Authors: A. M., BAKKE MCKELLEP, M., Sanden, Danieli, Antonio, Acierno, Raffaele, G. I., Hemre, Maffia, Michele, A., Krogdahl
Format: Article in Journal/Newspaper
Language:English
Published: 2008
Subjects:
GM
Online Access:http://hdl.handle.net/11587/340239
https://doi.org/10.1016/j.rvsc.2007.06.008
Description
Summary:Physiological and health related responses to dietary inclusion of genetically modified (GM) full-fat soybean meal (Roundup Ready; GM-soy) and maize (MON810 Bt-maize; GM-maize), as well as non-parental, untransformed lines (nGM-soy and nGM-maize D2), were evaluated in farmed Atlantic salmon (Salmo salar L.) parr during the first 8 months of feeding. Significant effects of dietary GM presence were only found in intestinal Na+-dependent d-glucose uptake and SGLT1 protein level in the region pyloric caeca in which the highest values were found in the GM-soy, intermediate in the nGM-soy, and lowest in the standard FM fed groups. Data from this study confirm that GM soybeans (RRS) and maize (MON810) at inclusion levels of about 6% appear to be as safe as commercially available nGM soy and maize in diets for Atlantic salmon parr. Results from studies with higher inclusion levels and with non-modified, isogenic or near-isogenic parental lines as control groups are pending.