Metagenomic survey for viruses in Western Arctic caribou, Alaska, through iterative assembly of taxonomic units

Pathogen surveillance in animals does not provide a sufficient level of vigilance because it is generally confined to surveillance of pathogens with known economic impact in domestic animals and practically nonexistent in wildlife species. As most (re-)emerging viral infections originate from animal...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Schürch, A. (Anita), Schipper, D. (Debby), Bijl, M.A. (Maarten), Dau, J. (Jim), Beckmen, K. (Kimberlee), Schapendonk, C.M.E. (Claudia), Raj, V.S. (Stalin), Osterhaus, A.D.M.E. (Albert), Haagmans, B.L. (Bart), Tryland, M. (Morten), Smits, S.L. (Saskia)
Format: Article in Journal/Newspaper
Language:English
Published: 2014
Subjects:
Arctic
caribou
Alaska
Online Access:http://repub.eur.nl/pub/90419
https://doi.org/10.1371/journal.pone.0105227
Description
Summary:Pathogen surveillance in animals does not provide a sufficient level of vigilance because it is generally confined to surveillance of pathogens with known economic impact in domestic animals and practically nonexistent in wildlife species. As most (re-)emerging viral infections originate from animal sources, it is important to obtain insight into viral pathogens present in the wildlife reservoir from a public health perspective. When monitoring living, free-ranging wildlife for viruses, sample collection can be challenging and availability of nucleic acids isolated from samples is often limited. The development of viral metagenomics platforms allows a more comprehensive i

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