Relative immunocompetence of the newborn harbour seal, phoca vitulina

The immune system of many mammalian species is not fully developed at birth, with newborns obtaining temporary immunological protection from maternal antibodies. Little is known of the immune system of the harbour seal, and developmental aspects of its immune system have not been systematically stud...

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Bibliographic Details
Published in:Veterinary Immunology and Immunopathology
Main Authors: Ross, P.S. (Peter), Swart, R.L. (Rik) de, Visser, I.K.G. (Ilona), Vedder, E.J. (Lies), Murk, W., Bowen, W.D., Osterhaus, A.D.M.E. (Albert)
Format: Article in Journal/Newspaper
Language:English
Published: 1994
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Online Access:http://repub.eur.nl/pub/39826
https://doi.org/10.1016/0165-2427(94)90077-9
Description
Summary:The immune system of many mammalian species is not fully developed at birth, with newborns obtaining temporary immunological protection from maternal antibodies. Little is known of the immune system of the harbour seal, and developmental aspects of its immune system have not been systematically studied. We collected blood and milk samples from nine free-ranging mother-pup pairs throughout the lactation period on Sable Island, Canada, in an effort to characterise developmental aspects of the immune system of this newborn pinniped. Pup lymphocytes responded stronger to the mitogens concanavalin A, phytohaemagglutinin, and pokeweed mitogen than