Prenatal exposure to aluminum and status of selected essential trace elements in rural South African women at delivery

This study sought to evaluate the in utero exposure to aluminum and status of selected trace elements in South African women at delivery since aluminum is known to be toxic in all developmental stages even at low concentrations. Serum aluminum was negatively correlated with aluminum in urine, both u...

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Bibliographic Details
Published in:International Journal of Environmental Research and Public Health
Main Authors: Rollin, Halina B., Nogueira, Claudina, Olutola, Bukola Ganiyat, Channa, Kalavati, Odland, Jon Oyvind
Format: Article in Journal/Newspaper
Language:English
Published: MDPI Publishing 2018
Subjects:
Aluminum
Essential trace elements
In utero exposure
Birth outcomes
Maternal serum
Maternal urine
South Africa (SA)
Zinc blood level
Arctic
Norway
AMAP
Online Access:http://hdl.handle.net/2263/69172
https://doi.org/10.3390/ijerph15071494
Description
Summary:This study sought to evaluate the in utero exposure to aluminum and status of selected trace elements in South African women at delivery since aluminum is known to be toxic in all developmental stages even at low concentrations. Serum aluminum was negatively correlated with aluminum in urine, both uncorrected and corrected for creatinine, which suggests the retention of aluminum in body stores. Serum copper and zinc levels were found to be high in this study population. Serum copper levels were negatively correlated with aluminum in serum ( =0.095; p = 0.05). There was a marginal negative correlation between aluminum levels in serum and manganese levels in whole blood ( = 0.087; p = 0.08). Copper levels in maternal serum were negatively correlated with birth weight and the length of neonates. There were a number of positive correlations between maternal characteristics and birth outcomes. Mothers who consumed root vegetables frequently appeared to be protected from aluminum retention and increased body burden since their serum aluminum levels were found to be significantly lower. The findings of the current study can be used as a baseline for further research on aluminum exposure and its associated interactions and outcomes in vulnerable populations. The National Research Foundation (NRF), South Africa and the Research Council of Norway (Grant 114962), Halina B. Röllin, SA PI), the Arctic Monitoring and Assessment Programme (AMAP) and the Norwegian Royal Ministry for Foreign Affairs (RER-09/126, Jon Ø Odland). http://www.mdpi.com/journal/ijerph am2019 School of Health Systems and Public Health (SHSPH)

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