Phocine Distemper Virus: Current Knowledge and Future Directions
Phocine distemper virus (PDV) was first recognized in 1988 following a massive epidemic in harbor and grey seals in north-western Europe. Since then, the epidemiology of infection in North Atlantic and Arctic pinnipeds has been investigated. In the western North Atlantic endemic infection in harp an...
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Online Access: | http://hdl.handle.net/11577/3061499 https://doi.org/10.3390/v6125093 |
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ftunivpadovairis:oai:www.research.unipd.it:11577/3061499 2024-04-14T08:07:18+00:00 Phocine Distemper Virus: Current Knowledge and Future Directions Pádraig Duignan Marie Françoise Van Bressem Jason Baker Michelle Barbieri Kathleen Colegrove Sylvain De Guise Rik de Swart Giovanni Di Guardo Andrew Dobson W. Duprex Greg Early Deborah Fauquier Tracey Goldstein Simon Goodman Bryan Grenfell Kátia Groch Frances Gulland Ailsa Hall Brenda Jensen Karina Lamy Keith Matassa Sinead Morris Ole Nielsen David Rotstein Teresa Rowles Jeremy Saliki Ursula Siebert Thomas Waltzek James Wellehan MAZZARIOL, SANDRO Pádraig, Duignan Marie Françoise Van, Bressem Jason, Baker Michelle, Barbieri Kathleen, Colegrove Sylvain De, Guise Rik de, Swart Giovanni Di, Guardo Andrew, Dobson W., Duprex Greg, Early Deborah, Fauquier Tracey, Goldstein Simon, Goodman Bryan, Grenfell Kátia, Groch Frances, Gulland Ailsa, Hall Brenda, Jensen Karina, Lamy Keith, Matassa Mazzariol, Sandro Sinead, Morri Ole, Nielsen David, Rotstein Teresa, Rowle Jeremy, Saliki Ursula, Siebert Thomas, Waltzek James, Wellehan 2014 ELETTRONICO http://hdl.handle.net/11577/3061499 https://doi.org/10.3390/v6125093 eng eng info:eu-repo/semantics/altIdentifier/pmid/25533658 info:eu-repo/semantics/altIdentifier/wos/WOS:000346834500015 volume:6 firstpage:5093 lastpage:5134 journal:VIRUSES http://hdl.handle.net/11577/3061499 doi:10.3390/v6125093 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84919819797 info:eu-repo/semantics/openAccess Morbilliviru Seal CD150/SLAM immunity Pathogenesis info:eu-repo/semantics/article 2014 ftunivpadovairis https://doi.org/10.3390/v6125093 2024-03-21T19:38:16Z Phocine distemper virus (PDV) was first recognized in 1988 following a massive epidemic in harbor and grey seals in north-western Europe. Since then, the epidemiology of infection in North Atlantic and Arctic pinnipeds has been investigated. In the western North Atlantic endemic infection in harp and grey seals predates the European epidemic, with relatively small, localized mortality events occurring primarily in harbor seals. By contrast, PDV seems not to have become established in European harbor seals following the 1988 epidemic and a second event of similar magnitude and extent occurred in 2002. PDV is a distinct species within the Morbillivirus genus with minor sequence variation between outbreaks over time. There is now mounting evidence of PDV-like viruses in the North Pacific/Western Arctic with serological and molecular evidence of infection in pinnipeds and sea otters. However, despite the absence of associated mortality in the region, there is concern that the virus may infect the large Pacific harbor seal and northern elephant seal populations or the endangered Hawaiian monk seals. Here, we review the current state of knowledge on PDV with particular focus on developments in diagnostics, pathogenesis, immune response, vaccine development, phylogenetics and modeling over the past 20 years. Article in Journal/Newspaper Arctic Elephant Seal harbor seal North Atlantic Padua Research Archive (IRIS - Università degli Studi di Padova) Arctic Pacific Viruses 6 12 5093 5134 |
institution |
Open Polar |
collection |
Padua Research Archive (IRIS - Università degli Studi di Padova) |
op_collection_id |
ftunivpadovairis |
language |
English |
topic |
Morbilliviru Seal CD150/SLAM immunity Pathogenesis |
spellingShingle |
Morbilliviru Seal CD150/SLAM immunity Pathogenesis Pádraig Duignan Marie Françoise Van Bressem Jason Baker Michelle Barbieri Kathleen Colegrove Sylvain De Guise Rik de Swart Giovanni Di Guardo Andrew Dobson W. Duprex Greg Early Deborah Fauquier Tracey Goldstein Simon Goodman Bryan Grenfell Kátia Groch Frances Gulland Ailsa Hall Brenda Jensen Karina Lamy Keith Matassa Sinead Morris Ole Nielsen David Rotstein Teresa Rowles Jeremy Saliki Ursula Siebert Thomas Waltzek James Wellehan MAZZARIOL, SANDRO Phocine Distemper Virus: Current Knowledge and Future Directions |
topic_facet |
Morbilliviru Seal CD150/SLAM immunity Pathogenesis |
description |
Phocine distemper virus (PDV) was first recognized in 1988 following a massive epidemic in harbor and grey seals in north-western Europe. Since then, the epidemiology of infection in North Atlantic and Arctic pinnipeds has been investigated. In the western North Atlantic endemic infection in harp and grey seals predates the European epidemic, with relatively small, localized mortality events occurring primarily in harbor seals. By contrast, PDV seems not to have become established in European harbor seals following the 1988 epidemic and a second event of similar magnitude and extent occurred in 2002. PDV is a distinct species within the Morbillivirus genus with minor sequence variation between outbreaks over time. There is now mounting evidence of PDV-like viruses in the North Pacific/Western Arctic with serological and molecular evidence of infection in pinnipeds and sea otters. However, despite the absence of associated mortality in the region, there is concern that the virus may infect the large Pacific harbor seal and northern elephant seal populations or the endangered Hawaiian monk seals. Here, we review the current state of knowledge on PDV with particular focus on developments in diagnostics, pathogenesis, immune response, vaccine development, phylogenetics and modeling over the past 20 years. |
author2 |
Pádraig, Duignan Marie Françoise Van, Bressem Jason, Baker Michelle, Barbieri Kathleen, Colegrove Sylvain De, Guise Rik de, Swart Giovanni Di, Guardo Andrew, Dobson W., Duprex Greg, Early Deborah, Fauquier Tracey, Goldstein Simon, Goodman Bryan, Grenfell Kátia, Groch Frances, Gulland Ailsa, Hall Brenda, Jensen Karina, Lamy Keith, Matassa Mazzariol, Sandro Sinead, Morri Ole, Nielsen David, Rotstein Teresa, Rowle Jeremy, Saliki Ursula, Siebert Thomas, Waltzek James, Wellehan |
format |
Article in Journal/Newspaper |
author |
Pádraig Duignan Marie Françoise Van Bressem Jason Baker Michelle Barbieri Kathleen Colegrove Sylvain De Guise Rik de Swart Giovanni Di Guardo Andrew Dobson W. Duprex Greg Early Deborah Fauquier Tracey Goldstein Simon Goodman Bryan Grenfell Kátia Groch Frances Gulland Ailsa Hall Brenda Jensen Karina Lamy Keith Matassa Sinead Morris Ole Nielsen David Rotstein Teresa Rowles Jeremy Saliki Ursula Siebert Thomas Waltzek James Wellehan MAZZARIOL, SANDRO |
author_facet |
Pádraig Duignan Marie Françoise Van Bressem Jason Baker Michelle Barbieri Kathleen Colegrove Sylvain De Guise Rik de Swart Giovanni Di Guardo Andrew Dobson W. Duprex Greg Early Deborah Fauquier Tracey Goldstein Simon Goodman Bryan Grenfell Kátia Groch Frances Gulland Ailsa Hall Brenda Jensen Karina Lamy Keith Matassa Sinead Morris Ole Nielsen David Rotstein Teresa Rowles Jeremy Saliki Ursula Siebert Thomas Waltzek James Wellehan MAZZARIOL, SANDRO |
author_sort |
Pádraig Duignan |
title |
Phocine Distemper Virus: Current Knowledge and Future Directions |
title_short |
Phocine Distemper Virus: Current Knowledge and Future Directions |
title_full |
Phocine Distemper Virus: Current Knowledge and Future Directions |
title_fullStr |
Phocine Distemper Virus: Current Knowledge and Future Directions |
title_full_unstemmed |
Phocine Distemper Virus: Current Knowledge and Future Directions |
title_sort |
phocine distemper virus: current knowledge and future directions |
publishDate |
2014 |
url |
http://hdl.handle.net/11577/3061499 https://doi.org/10.3390/v6125093 |
geographic |
Arctic Pacific |
geographic_facet |
Arctic Pacific |
genre |
Arctic Elephant Seal harbor seal North Atlantic |
genre_facet |
Arctic Elephant Seal harbor seal North Atlantic |
op_relation |
info:eu-repo/semantics/altIdentifier/pmid/25533658 info:eu-repo/semantics/altIdentifier/wos/WOS:000346834500015 volume:6 firstpage:5093 lastpage:5134 journal:VIRUSES http://hdl.handle.net/11577/3061499 doi:10.3390/v6125093 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84919819797 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.3390/v6125093 |
container_title |
Viruses |
container_volume |
6 |
container_issue |
12 |
container_start_page |
5093 |
op_container_end_page |
5134 |
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1796304577355579392 |