TOLERANCE SHOWN BY Rattus rattus TO AN ANTICOAGULANT RODENTICIDE

Apart from using 0.005% concentration, the recommended field dose of 0.025% of the anticoagulant is used along with an alternate food for individual rats for a varying number of days. Those that had survived were taken as tolerant, provided they showed an mg/kg intake beyond the tolerance limit, sur...

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Bibliographic Details
Main Authors: Deoras, P. J., Chaturvedi, G. C., Vad, N. E., Renapurkar, D. M.
Format: Text
Language:unknown
Published: DigitalCommons@University of Nebraska - Lincoln 1972
Subjects:
Environmental Health and Protection
Rattus rattus
Online Access:https://digitalcommons.unl.edu/vpc5/32
https://digitalcommons.unl.edu/context/vpc5/article/1031/viewcontent/31_Deoras_and_Chaturvedi.pdf
Description
Summary:Apart from using 0.005% concentration, the recommended field dose of 0.025% of the anticoagulant is used along with an alternate food for individual rats for a varying number of days. Those that had survived were taken as tolerant, provided they showed an mg/kg intake beyond the tolerance limit, survived a six days of feeding, exhibited bait-shyness and did not exhibit hemorrhage after death. In determining the criteria for tolerance to an anticoagulant by a rat, one should take into account four composite factors. These are, six days of even 0.025% feeding, bait-shyness when alternate food is given, higher mg/kg intake than the tolerance level and a loss of intensive hemorrhage after death.

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