Starfish Saponins: part 54. Cytotoxic asterosaponins from an Antarctic starfish of the family Echinasteridae

An investigation of the polar extracts from a starfish, collected in the Antarctic Sea, and identified as belonging to the Echinasteridae family, has led to the isolation of seven sulphated asterosaponins. Five are new compounds. The isolated asterosaponins have been found to be cytotoxic against hu...

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Bibliographic Details
Main Authors: DE MARINO, SIMONA, ZOLLO, FRANCO, L. Minale, M. Iorizzi, V. Le Bert, C. Roussakis
Other Authors: DE MARINO, Simona, L., Minale, Zollo, Franco, M., Iorizzi, V., Le Bert, C., Roussakis
Format: Article in Journal/Newspaper
Language:English
Published: 1996
Subjects:
Sulphated asterosaponin
Human bronchopulmunary non-small-cell-lung carcinoma cell
Antarctic starfish
Antarctic
The Antarctic
Antarc*
Online Access:http://hdl.handle.net/11588/374141
Description
Summary:An investigation of the polar extracts from a starfish, collected in the Antarctic Sea, and identified as belonging to the Echinasteridae family, has led to the isolation of seven sulphated asterosaponins. Five are new compounds. The isolated asterosaponins have been found to be cytotoxic against human bronchopulmunary non-small-cell-lung carcinoma cells at IC50 < 3.3 mu g/ml.

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