Investigation of the polar steroids from an Antarctic starfish of the family Echinasteridae: isolation of twenty seven polyhydroxysteroids and steroidal oligoglycosides, structures and biological activities

An investigation of the extracts from a starfish collected in the Antarctic Sea, Echinasteridae family, has led to the isolation of thirteen glycosides of polyhydroxysteroids (1-13), fourteen polyhydroxysteroids (14-27), which are the subject of this report, and seven asterosaponins (penta-and hexa-...

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Bibliographic Details
Main Authors: M. Iorizzi, L. Minale, V. Le Bert, C. Roussakis, DE MARINO, SIMONA, ZOLLO, FRANCO
Other Authors: M., Iorizzi, DE MARINO, Simona, L., Minale, Zollo, Franco, V., Le Bert, C., Roussakis
Format: Article in Journal/Newspaper
Language:English
Published: 1996
Subjects:
Glycosides of polyhydroxysteroid
Polyhyoxysteroid
human non-small-cell lung carcinoma cells
Antarctic
The Antarctic
Antarc*
Online Access:http://hdl.handle.net/11588/374135
https://doi.org/10.1016/0040-4020(96)00618
http://www.sciencedirect.com/science/article/pii/0040402096006187
Description
Summary:An investigation of the extracts from a starfish collected in the Antarctic Sea, Echinasteridae family, has led to the isolation of thirteen glycosides of polyhydroxysteroids (1-13), fourteen polyhydroxysteroids (14-27), which are the subject of this report, and seven asterosaponins (penta-and hexa-saccharides), described in a previous paper. A selection of fifteen compounds were tested against human non-small-cell lung carcinoma cells and found to be moderately cytotoxic.

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