Starfish saponins. 55. Isolation, structure elucidation, and biological activity of the steroid oligoglycosides from an Antarctic starfish of the family Asteriidae

This paper reports an analysis of the chemical constituents from an Antarctic starfish of the family Asteriidae. Different steroid glycoside types are represented among its constituents, including the five hexaglycoside steroidal sulfates asteriidosides A-E (1-5), and the two nonsulfated diglycoside...

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Bibliographic Details
Published in:Journal of Natural Products
Main Authors: DE MARINO, SIMONA, ZOLLO, FRANCO, M. Iorizzi, E. Palagiano, C. Roussakis
Other Authors: DE MARINO, Simona, M., Iorizzi, E., Palagiano, Zollo, Franco, C., Roussakis
Format: Article in Journal/Newspaper
Language:English
Published: 1998
Subjects:
Asteriidae
Steroidal glycoside
Asterosaponins
Antarc*
Antarctic
Online Access:http://hdl.handle.net/11588/357185
https://doi.org/10.1021/np970500e
http://pubs.acs.org/doi/pdf/10.1021/np970500e
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Summary:This paper reports an analysis of the chemical constituents from an Antarctic starfish of the family Asteriidae. Different steroid glycoside types are represented among its constituents, including the five hexaglycoside steroidal sulfates asteriidosides A-E (1-5), and the two nonsulfated diglycosides asteriidoside F (6) and G (7). Also present are the two sulfated diglycosides asteriidoside H (8) and I (9) and one sulfated monoglycoside asteriidoside L (10). Eight of the compounds were tested against human nonsmall-cell lung carcinoma cells (NSCLC-L16) and found to be moderately cytotoxic.

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