Relation between serum xenobiotic induced receptor activities and DNA damage and sperm apoptotic markers in European and Inuit populations

Persistent organic pollutants (POPs) can interfere with hormone activities and are suspected as endocrine disrupters involved in, e.g. reproductive disorders. We investigated the possible relation between the actual integrated serum xenoestrogenic, xenoandrogenic and aryl hydrocarbon receptor activi...

Full description

Bibliographic Details
Published in:Toxicology Letters
Main Authors: Long M., Stronati A., Bizzaro D., Kruger T., Hjelmborg P. S., Spano M., Giwercman A., Toft G., Bonde J. P., Bonefeld Jorgensen E. C., MANICARDI, Gian Carlo
Other Authors: Long, M., Stronati, A., Bizzaro, D., Kruger, T., Manicardi, Gian Carlo, Hjelmborg, P. S., Spano, M., Giwercman, A., Toft, G., Bonde, J. P., Bonefeld Jorgensen, E. C.
Format: Article in Journal/Newspaper
Language:English
Published: ELSEVIER IRELAND LTD 2008
Subjects:
spermatozoa
xenobiotic
male infertility
Greenland
inuit
inuits
Online Access:http://hdl.handle.net/11380/611490
https://doi.org/10.1016/j.toxlet.2008.06.193
Description
Summary:Persistent organic pollutants (POPs) can interfere with hormone activities and are suspected as endocrine disrupters involved in, e.g. reproductive disorders. We investigated the possible relation between the actual integrated serum xenoestrogenic, xenoandrogenic and aryl hydrocarbon receptor activities and the sperm DNA damage and sperm apoptotic markers of 262 adult males (54 Inuits from Greenland, 69 from Warsaw (Poland), 81 from Sweden and 58 from Kharkiv (Ukraine) exposed to different levels of POPs.

Similar Items