A convenient synthesis of oxandrolone through a regioselective Candida antarctica lipase-catalyzed transformation

The use of a regioselective CAL-catalyzed transformation of a suitable intermediate allowed a convenient synthesis of oxandrolone, an anabolic hormone actualy employed to improve the quality of life for patients with HIV-infections

Bibliographic Details
Published in:Tetrahedron: Asymmetry
Main Authors: P. Ferraboschi, D. Colombo, P. Prestileo
Format: Article in Journal/Newspaper
Language:English
Published: Pergamon Elsevier Science 2003
Subjects:
Online Access:http://hdl.handle.net/2434/26231
https://doi.org/10.1016/S0957-4166(03)00593-7
Description
Summary:The use of a regioselective CAL-catalyzed transformation of a suitable intermediate allowed a convenient synthesis of oxandrolone, an anabolic hormone actualy employed to improve the quality of life for patients with HIV-infections