Identification of Reproduction-Specific genes associated with maturation and estrogen exposure in a marine bivalve Mytilus edulis

Background: While it is established that vertebrate-like steroids, particularly estrogens (estradiol, estrone) and androgens (testosterone), are present in various tissues of molluscs, it is still unclear what role these play in reproductive endocrinology in such organisms. This is despite the signi...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Rotchell, Jeanette M., Ciocan, Corina M., Cubero-Leon, Elena, Minier, Christophe
Other Authors: Laudet, Vincent
Format: Article in Journal/Newspaper
Language:unknown
Published: Public Library of Science 2011
Subjects:
Aquatic toxicology
Oyster crassostrea-gigas
Patinopecten-yessoensis
Messenger-rna expression
Serotonin-receptor
Sex steroids
Vitellogenin protein
Estradiol-17-beta metabolism
Specialist Research - Other
Crassostrea gigas
Online Access:https://hull-repository.worktribe.com/file/464291/1/Published%20article.pdf
https://hull-repository.worktribe.com/output/464291
https://doi.org/10.1371/journal.pone.0022326
Description
Summary:Background: While it is established that vertebrate-like steroids, particularly estrogens (estradiol, estrone) and androgens (testosterone), are present in various tissues of molluscs, it is still unclear what role these play in reproductive endocrinology in such organisms. This is despite the significant commercial shellfishery interest in several bivalve species and their decline. Methodology/Principal Findings: Using suppression subtraction hybridisation of mussel gonad samples at two stages (early and mature) of gametogenesis and (in parallel) following controlled laboratory estrogen exposure, we isolate several differentially regulated genes including testis-specific kinases, vitelline lysin and envelope sequences. Conclusions: The differentially expressed mRNAs isolated provide evidence that mussels may be impacted by exogenous estrogen exposure.

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