Novel chromosomal polymorphisms identified in North American Atlantic salmon (Salmo salar) using a high-density linkage map generated from a 50K SNP array

Atlantic salmon (Salmo salar) contain a complex genome structure that may present polymorphic chromosomal rearrangements between different populations. For example, European and North American populations of S. salar have been shown to exhibit 29 and 27 chromosomes, respectively. Genetic linkage map...

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Bibliographic Details
Main Author: Mac Leod-Bigley, Melissa
Other Authors: Boulding, Elizabeth
Format: Thesis
Language:English
Published: University of Guelph 2020
Subjects:
Online Access:http://hdl.handle.net/10214/17750
Description
Summary:Atlantic salmon (Salmo salar) contain a complex genome structure that may present polymorphic chromosomal rearrangements between different populations. For example, European and North American populations of S. salar have been shown to exhibit 29 and 27 chromosomes, respectively. Genetic linkage maps allow us to better study and understand these chromosomal rearrangements. My goal was to construct high-density SNP-based linkage maps for North American S. salar using the R package OneMap. Individual maps contained an average of 13,114 SNPs for each of nine full-sibling families, with lengths of female and male maps averaging 3,034.83 cM and 1659.11 cM, respectively, with an average female to male ratio of 1.83:1. My findings provide higher resolution mapping that allow for identification of the correct orientation of three chromosomal polymorphisms already observed in North American S. salar (Ssa01p/23, Ssa08/29, Ssa26/28) as well as evidence for three novel chromosomal polymorphisms (Ssa06, Ssa11, and Ssa16). Genomic Applications Partnership Program Cooke Aquaculture Inc. Centre for Integrative Genetics, Norwegian University of Lifesciences 2021-01-31