Hydroxy functional acrylates: enzymatic synthesis and free radical polymerization

• Published in: Macromolecular Symposia
• Main Authors: Popescu, Dragos, Hoogenboom, Richard, Keul, Helmut, Möller, Martin
• Other Authors: Stelzer, F, Wiesbrock, E
• Format: Conference Object
• Language: English
• Published: Wiley-VCH 2010
• Subjects: Chemistry; DRUG-DELIVERY; TEMPERATURE; radical polymerization; functional monomers and polymers; enzyme-catalyzed transacylation; candida antarctica lipase-B; Antarc*; Antarctica
• Online Access: https://biblio.ugent.be/publication/1202298; http://hdl.handle.net/1854/LU-1202298; https://doi.org/10.1002/masy.201051008; https://biblio.ugent.be/publication/1202298/file/1202327

Hydroxy functional acrylates were prepared via transacylation of methyl acrylate with 1,2,6-hexanetriol catalyzed by Candida antarctica lipase B. Under the applied reaction conditions, 70% of the substrate was converted into hydroxy functional acrylates. In a subsequent step, after filtration of the enzyme, the monomer mixture containing methyl acrylate and the new monomers was polymerized via free radical polymerization resulting in a functional copolymer with M-n = 14500 g/mol.