Isolation and multilocus genotyping of Toxoplasma gondii in seronegative rodents in Brazil

Paranaense University (UNIPAR) UNIPAR: 14707/2009 Synanthropic rodents, mainly rats and mice, become ecologically associated with men due to changes in their ecosystems caused by human activities. These animals may take part in the epidemiological cycles of several diseases, including toxoplasmosis....

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Bibliographic Details
Published in:Veterinary Parasitology
Main Authors: Araujo, Jacqueline B., da Silva, Aristeu V., Rosa, Ronaldo C., Mattei, Rodrigo J., da Silva, Rodrigo C., Richini-Pereira, Virginia B., Langoni, Hélio
Other Authors: Universidade Estadual Paulista (UNESP)
Format: Article in Journal/Newspaper
Language:English
Published: Elsevier B.V. 2010
Subjects:
Toxoplasmosis
Mus musculus
Rattus rattus
Antibody detection
Bioassay
Genotyping
Online Access:http://hdl.handle.net/11449/13916
https://doi.org/10.1016/j.vetpar.2010.08.039
Description
Summary:Paranaense University (UNIPAR) UNIPAR: 14707/2009 Synanthropic rodents, mainly rats and mice, become ecologically associated with men due to changes in their ecosystems caused by human activities. These animals may take part in the epidemiological cycles of several diseases, including toxoplasmosis. The presence of serum antibodies to Toxoplasma gondii in 43 rodents captured in the urban area of Umuarama, PR, Brazil, was verified by modified agglutination test (MAT). Brain and heart samples were also collected and bioassayed in mice for the isolation of the parasite. Isolated samples were analyzed by 12 multilocus genotyping. Although all rodents were seronegative, the parasite was isolated in one mouse (Mus musculus) and one rat (Rattus rattus). Genotyping showed that these samples were similar to those previously isolated from cats in the state of Parana, Brazil. (C) 2010 Elsevier B.V. All rights reserved.

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