Exploratory study on sequestration of some essential metals by indigo carmine food dye

Indigo carmine forms a stable complex with different ions, and the stability constant of the complexes were evaluated as log K equal to 5.75; 5.00; 4.89 and 3.89 for complexes with Cu(II), Ni(II), Co(II) and Zn(II) ions, respectively, in 0.1 mol L -1 carbonate buffer solution at pH 10. The interacti...

Full description

Bibliographic Details
Published in:Brazilian Journal of Pharmaceutical Sciences
Main Authors: Zanoni, Thalita Boldrin, Cardoso, Arnaldo Alves, Zanoni, Maria Valnice Boldrin, Ferreira, Antonio Aparecido Pupim
Other Authors: Universidade Estadual Paulista (UNESP)
Format: Other/Unknown Material
Language:English
Published: 2014
Subjects:
Copper/determination
Food dye/complexation
Indigo carmine
Metal sequestration
Spectrophotometric analysis
buffer
carbonic acid
cobalt
copper ion
food dye
gluconate copper
nickel
zinc ion
alkalinity
chemical analysis
chemical interaction
chemical structure
complex formation
pH
spectrophotometry
stoichiometry
Carbonic acid
Online Access:http://acervodigital.unesp.br/handle/11449/71907
http://hdl.handle.net/11449/71907
https://doi.org/10.1590/S1984-82502010000400014
Description
Summary:Indigo carmine forms a stable complex with different ions, and the stability constant of the complexes were evaluated as log K equal to 5.75; 5.00; 4.89 and 3.89 for complexes with Cu(II), Ni(II), Co(II) and Zn(II) ions, respectively, in 0.1 mol L -1 carbonate buffer solution at pH 10. The interaction between Cu(II) ions and indigo carmine (IC) in alkaline medium resulted in the formation of the Cu 2(IC) complex, measured by the spectrophotometric method, with a stoichiometric ratio between indigo carmine and metal ions of 2:1 (metal-ligand). The reported method has also been successfully tested for determination of copper in pharmaceutical compounds based on copper-gluconate without pre-treatment.

Similar Items