Downsizing Class II Lasso Peptides : Genome Mining-Guided Isolation of Huascopeptin Containing the First Gly1-Asp7 Macrocycle

This work was financially supported by the CONICYT PFCHA/DOCTORADO BECAS CHILE/2016-21160585 fellowship and CONICYT Basal Centre Grant for the Centre for Biotechnology and Bioengineering, CeBiB (FB0001). S.A.J. thanks the University of Aberdeen for providing an Elphinstone Scholarship. We thank the...

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Bibliographic Details
Published in:The Journal of Organic Chemistry
Main Authors: Cortés-Albayay, Carlos, Jarmusch, Scott A, Trusch, Franziska, Ebel, Rainer, Andrews, Barbara A, Jaspars, Marcel, Asenjo, Juan A
Other Authors: University of Aberdeen.Natural & Computing Sciences, University of Aberdeen.Medical Sciences, University of Aberdeen.Chemistry
Format: Article in Journal/Newspaper
Language:English
Published: 2020
Subjects:
QD Chemistry
Organic Chemistry
QD
Arctic University of Norway
University of Tromsø
Online Access:https://hdl.handle.net/2164/15791
https://doi.org/10.1021/acs.joc.9b02231
http://www.scopus.com/inward/record.url?scp=85079095898&partnerID=8YFLogxK
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Summary:This work was financially supported by the CONICYT PFCHA/DOCTORADO BECAS CHILE/2016-21160585 fellowship and CONICYT Basal Centre Grant for the Centre for Biotechnology and Bioengineering, CeBiB (FB0001). S.A.J. thanks the University of Aberdeen for providing an Elphinstone Scholarship. We thank the Scottish High-Field NMR (SHF NMR) Centre at the University of Edinburgh for NMR experiments. We also thank Dr. Paul Herron (Strathclyde Institute of Pharmacy and Biomedical Sciences) for genome sequencing. Additionally, we thank Kirsti Helland, Marte Albrigsten, and Jeanette Andersen (University of Tromsø - The Arctic University of Norway) for conducting biologicalassays. Finally, we thank Dr. Imen Nouioui and Dr. Cristina Dorador for their feedback during manuscript preparation. Peer reviewed

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