Vaccination against viral hemorrhagic septicemia and infectious hematopoietic necrosis
International audience Viral hemorrhagic septicemia (VHS) and infectious hematopoietic necrosis (IHN) are very contagious viral diseases leading to high mortality mainly, but not exclusively, in young salmonid fish. Although research on vaccine development has been ongoing for more than four decades...
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ftuniparissaclay:oai:HAL:hal-02799157v1 2023-05-15T15:32:08+02:00 Vaccination against viral hemorrhagic septicemia and infectious hematopoietic necrosis Biacchesi, Stephane Bremont, Michel Unité de recherche Virologie et Immunologie Moléculaires (VIM (UR 0892)) Institut National de la Recherche Agronomique (INRA) 2014 https://hal.inrae.fr/hal-02799157 en eng HAL CCSD Blackwell Science ISBN: 978-1-118-80692-0 978-0-470-67455-0 hal-02799157 https://hal.inrae.fr/hal-02799157 PRODINRA: 353967 WOS: 000354894300025 Fish Vaccination https://hal.inrae.fr/hal-02799157 Fish Vaccination, Blackwell Science, 14 p., 2014, 978-1-118-80692-0 978-0-470-67455-0 http://eu.wiley.com/WileyCDA/WileyTitle/productCd-0470674555.html [SDV]Life Sciences [q-bio] info:eu-repo/semantics/bookPart Book sections 2014 ftuniparissaclay 2022-10-11T19:11:07Z International audience Viral hemorrhagic septicemia (VHS) and infectious hematopoietic necrosis (IHN) are very contagious viral diseases leading to high mortality mainly, but not exclusively, in young salmonid fish. Although research on vaccine development has been ongoing for more than four decades, no mass delivery vaccine against these two important pathogens is yet available. Several candidate vaccines, based on inactivated virus, recombinant G protein, attenuated virus strains, and DNA vectors have been proved to be efficient to induce specific and long-lasting protective immunity in fish. A DNA vaccine against IHNV has recently been licensed for commercial use in Atlantic salmon in Canada. Nevertheless, the commercialization of this vaccine in Europe is not approved and a mass delivery system for vaccination of fish fry is required. In parallel, reverse genetics systems have allowed the generation of promising multivalent live attenuated vaccines. Additional work is needed to improve the safety of such vaccines. Book Part Atlantic salmon Archives ouvertes de Paris-Saclay Canada |
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Archives ouvertes de Paris-Saclay |
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English |
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[SDV]Life Sciences [q-bio] |
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[SDV]Life Sciences [q-bio] Biacchesi, Stephane Bremont, Michel Vaccination against viral hemorrhagic septicemia and infectious hematopoietic necrosis |
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[SDV]Life Sciences [q-bio] |
description |
International audience Viral hemorrhagic septicemia (VHS) and infectious hematopoietic necrosis (IHN) are very contagious viral diseases leading to high mortality mainly, but not exclusively, in young salmonid fish. Although research on vaccine development has been ongoing for more than four decades, no mass delivery vaccine against these two important pathogens is yet available. Several candidate vaccines, based on inactivated virus, recombinant G protein, attenuated virus strains, and DNA vectors have been proved to be efficient to induce specific and long-lasting protective immunity in fish. A DNA vaccine against IHNV has recently been licensed for commercial use in Atlantic salmon in Canada. Nevertheless, the commercialization of this vaccine in Europe is not approved and a mass delivery system for vaccination of fish fry is required. In parallel, reverse genetics systems have allowed the generation of promising multivalent live attenuated vaccines. Additional work is needed to improve the safety of such vaccines. |
author2 |
Unité de recherche Virologie et Immunologie Moléculaires (VIM (UR 0892)) Institut National de la Recherche Agronomique (INRA) |
format |
Book Part |
author |
Biacchesi, Stephane Bremont, Michel |
author_facet |
Biacchesi, Stephane Bremont, Michel |
author_sort |
Biacchesi, Stephane |
title |
Vaccination against viral hemorrhagic septicemia and infectious hematopoietic necrosis |
title_short |
Vaccination against viral hemorrhagic septicemia and infectious hematopoietic necrosis |
title_full |
Vaccination against viral hemorrhagic septicemia and infectious hematopoietic necrosis |
title_fullStr |
Vaccination against viral hemorrhagic septicemia and infectious hematopoietic necrosis |
title_full_unstemmed |
Vaccination against viral hemorrhagic septicemia and infectious hematopoietic necrosis |
title_sort |
vaccination against viral hemorrhagic septicemia and infectious hematopoietic necrosis |
publisher |
HAL CCSD |
publishDate |
2014 |
url |
https://hal.inrae.fr/hal-02799157 |
geographic |
Canada |
geographic_facet |
Canada |
genre |
Atlantic salmon |
genre_facet |
Atlantic salmon |
op_source |
Fish Vaccination https://hal.inrae.fr/hal-02799157 Fish Vaccination, Blackwell Science, 14 p., 2014, 978-1-118-80692-0 978-0-470-67455-0 http://eu.wiley.com/WileyCDA/WileyTitle/productCd-0470674555.html |
op_relation |
ISBN: 978-1-118-80692-0 978-0-470-67455-0 hal-02799157 https://hal.inrae.fr/hal-02799157 PRODINRA: 353967 WOS: 000354894300025 |
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