Evolutionary applications of MIRs and SINEs
It is believed that short interspersed elements (SINEs) are irreversibly inserted into genomes. We use this concept to try to deduce the evolution of whales using sequence and hybridization studies. The observation that microsatellites are associated with SINEs lead us to screen sequences surroundin...
Published in: | Animal Genetics |
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1999
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Online Access: | https://hdl.handle.net/11370/ab0f8aaa-d7ee-4322-b70e-5573e3572c13 https://research.rug.nl/en/publications/ab0f8aaa-d7ee-4322-b70e-5573e3572c13 https://doi.org/10.1046/j.1365-2052.1999.00388.x |
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ftunigroningenpu:oai:pure.rug.nl:publications/ab0f8aaa-d7ee-4322-b70e-5573e3572c13 2024-06-02T08:04:16+00:00 Evolutionary applications of MIRs and SINEs Buchanan, F Crawford, A Strobeck, C Palsboll, P Plante, Y 1999-02 https://hdl.handle.net/11370/ab0f8aaa-d7ee-4322-b70e-5573e3572c13 https://research.rug.nl/en/publications/ab0f8aaa-d7ee-4322-b70e-5573e3572c13 https://doi.org/10.1046/j.1365-2052.1999.00388.x eng eng https://research.rug.nl/en/publications/ab0f8aaa-d7ee-4322-b70e-5573e3572c13 info:eu-repo/semantics/closedAccess Buchanan , F , Crawford , A , Strobeck , C , Palsboll , P & Plante , Y 1999 , ' Evolutionary applications of MIRs and SINEs ' , Animal genetics , vol. 30 , no. 1 , pp. 47-50 . https://doi.org/10.1046/j.1365-2052.1999.00388.x artiodactyl cetacean mammalian-wide interspersed repeat short interspersed element MOLECULAR EVIDENCE MICROSATELLITES RETROPOSONS CETACEANS article 1999 ftunigroningenpu https://doi.org/10.1046/j.1365-2052.1999.00388.x 2024-05-07T19:28:23Z It is believed that short interspersed elements (SINEs) are irreversibly inserted into genomes. We use this concept to try to deduce the evolution of whales using sequence and hybridization studies. The observation that microsatellites are associated with SINEs lead us to screen sequences surrounding cetacean microsatellites for artiodactyl-derived SINEs. Two sequences that were thought to be cetacean SINEs and the bovine SINE were aligned for comparison to sequences flanking microsatellites from ungulates. The bovine SINE was observed only in ruminants while CetSINE1 and 2 were found in mammals. Hybridization studies using these three SINEs revealed that CetSINE1 was found in all ungulates and cetaceans with the strongest hybridization signal observed in the hippopotamus and beluga; CetSINE2 hybridized to all ungulate suborders, while the bovine SINE was only observed in Ruminantia. It is proposed that these putative SINEs are not 'generic' SINEs but mammalian-wide interspersed repeats (MIRs). Caution is urged: what initially appears to be a SINE may instead be a MIR and have reduced evolutionary resolving power. Article in Journal/Newspaper Beluga Beluga* University of Groningen research database Animal Genetics 30 1 47 51 |
institution |
Open Polar |
collection |
University of Groningen research database |
op_collection_id |
ftunigroningenpu |
language |
English |
topic |
artiodactyl cetacean mammalian-wide interspersed repeat short interspersed element MOLECULAR EVIDENCE MICROSATELLITES RETROPOSONS CETACEANS |
spellingShingle |
artiodactyl cetacean mammalian-wide interspersed repeat short interspersed element MOLECULAR EVIDENCE MICROSATELLITES RETROPOSONS CETACEANS Buchanan, F Crawford, A Strobeck, C Palsboll, P Plante, Y Evolutionary applications of MIRs and SINEs |
topic_facet |
artiodactyl cetacean mammalian-wide interspersed repeat short interspersed element MOLECULAR EVIDENCE MICROSATELLITES RETROPOSONS CETACEANS |
description |
It is believed that short interspersed elements (SINEs) are irreversibly inserted into genomes. We use this concept to try to deduce the evolution of whales using sequence and hybridization studies. The observation that microsatellites are associated with SINEs lead us to screen sequences surrounding cetacean microsatellites for artiodactyl-derived SINEs. Two sequences that were thought to be cetacean SINEs and the bovine SINE were aligned for comparison to sequences flanking microsatellites from ungulates. The bovine SINE was observed only in ruminants while CetSINE1 and 2 were found in mammals. Hybridization studies using these three SINEs revealed that CetSINE1 was found in all ungulates and cetaceans with the strongest hybridization signal observed in the hippopotamus and beluga; CetSINE2 hybridized to all ungulate suborders, while the bovine SINE was only observed in Ruminantia. It is proposed that these putative SINEs are not 'generic' SINEs but mammalian-wide interspersed repeats (MIRs). Caution is urged: what initially appears to be a SINE may instead be a MIR and have reduced evolutionary resolving power. |
format |
Article in Journal/Newspaper |
author |
Buchanan, F Crawford, A Strobeck, C Palsboll, P Plante, Y |
author_facet |
Buchanan, F Crawford, A Strobeck, C Palsboll, P Plante, Y |
author_sort |
Buchanan, F |
title |
Evolutionary applications of MIRs and SINEs |
title_short |
Evolutionary applications of MIRs and SINEs |
title_full |
Evolutionary applications of MIRs and SINEs |
title_fullStr |
Evolutionary applications of MIRs and SINEs |
title_full_unstemmed |
Evolutionary applications of MIRs and SINEs |
title_sort |
evolutionary applications of mirs and sines |
publishDate |
1999 |
url |
https://hdl.handle.net/11370/ab0f8aaa-d7ee-4322-b70e-5573e3572c13 https://research.rug.nl/en/publications/ab0f8aaa-d7ee-4322-b70e-5573e3572c13 https://doi.org/10.1046/j.1365-2052.1999.00388.x |
genre |
Beluga Beluga* |
genre_facet |
Beluga Beluga* |
op_source |
Buchanan , F , Crawford , A , Strobeck , C , Palsboll , P & Plante , Y 1999 , ' Evolutionary applications of MIRs and SINEs ' , Animal genetics , vol. 30 , no. 1 , pp. 47-50 . https://doi.org/10.1046/j.1365-2052.1999.00388.x |
op_relation |
https://research.rug.nl/en/publications/ab0f8aaa-d7ee-4322-b70e-5573e3572c13 |
op_rights |
info:eu-repo/semantics/closedAccess |
op_doi |
https://doi.org/10.1046/j.1365-2052.1999.00388.x |
container_title |
Animal Genetics |
container_volume |
30 |
container_issue |
1 |
container_start_page |
47 |
op_container_end_page |
51 |
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1800748902846038016 |